Drosophila Genetics and Notation

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Questions and Answers

In Drosophila, what does the symbol 'w+' typically represent in genetic notation?

  • The wild-type allele, such as for red eyes. (correct)
  • A mutated allele with an unknown phenotype.
  • A recessive allele that is lethal when homozygous.
  • The allele for white eyes.

How are human genes typically represented in genetic notation, as exemplified by the gene for Huntington's disease?

  • In all capital letters. (correct)
  • In italics with mixed-case letters.
  • Using Greek symbols.
  • In lowercase letters with a superscript.

What did Morgan observe in the F₂ generation that led him to conclude that eye color in flies is linked to sex?

  • All F₂ flies had white eyes, regardless of sex.
  • There was no clear pattern of inheritance in the F₂ generation.
  • The white-eye trait appeared only in males. (correct)
  • All F₂ flies had red eyes, but only males passed on the trait.

In Morgan's initial cross, he mated a white-eyed male fly with a red-eyed female fly. What phenotype was observed in the F₁ offspring, and what did this suggest?

<p>Red eyes; suggesting the wild-type allele is dominant. (B)</p> Signup and view all the answers

What phenotypic ratio did Morgan observe in the F₂ offspring when he bred the F₁ flies with each other?

<p>3:1 (A)</p> Signup and view all the answers

Why is the allele for white eyes in Drosophila symbolized by 'w'?

<p>Because it was the first mutant (non-wild type) discovered. (A)</p> Signup and view all the answers

If a researcher discovers a new mutant allele in fruit flies causing curly wings, following the established notation, how would this allele likely be symbolized?

<p>c (D)</p> Signup and view all the answers

According to the passage, what is the primary purpose of using specific notations for alleles and genes?

<p>To provide a universal system for genetic communication and clarity. (B)</p> Signup and view all the answers

If a new human genetic disease is discovered, and its gene is named 'XYZ', how would it typically be written in scientific literature?

<p>XYZ (D)</p> Signup and view all the answers

In a scenario where a researcher crosses two Drosophila flies and observes a novel phenotype appearing exclusively in the male offspring, what might the researcher hypothesize?

<p>The trait is X-linked. (B)</p> Signup and view all the answers

Flashcards

Drosophila Allele Notation

Notation system used to represent alleles in Drosophila (fruit flies). The gene's symbol is derived from the first mutant discovered.

Wild-Type Allele Symbol

Symbolizes the allele for the wild-type trait in Drosophila, such as w⁺ for red eyes.

Notation of Human Genes

Human genes are written in all capitals to distinguish them from other organisms' genes. Example: HTT for Huntington's disease.

Morgan's Fly Experiment

In the F1 generation, all offspring had red eyes, which suggests that this allele is dominant. The white-eyed trait appeared only in males of the F2 generation, which revealed that the eye color gene is linked to sex.

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F1 Generation

The first filial generation, which are the offspring resulting from a cross between two parental (P) organisms

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F2 Generation

The second filial generation, which results from a cross between two F1 individuals

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Dominant Allele

The allele that expresses its phenotypic effect even when heterozygous with a recessive allele; determines the phenotype in a heterozygote.

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Study Notes

  • A notation for symbolizing alleles in Drosophila, widely used for fruit flies, was invented.
  • For a character in flies, the gene takes its symbol from the first mutant discovered.
  • The allele for white eyes in Drosophila is symbolized by w.
  • A superscript + identifies the allele for the wild-type trait, such as w⁺ for the allele for red eyes.
  • Human genes are usually written in all capitals, like HTT for the gene in Huntington's disease.
  • More than one letter may be used for an allele, as in HTT.
  • A white-eyed male fly was mated with a red-eyed female
  • The F₁ offspring had red eyes meaning the wild-type allele is dominant
  • When the F₁ flies were bred, there was a classical 3:1 phenotypic ratio among the F₂ offspring
  • The white-eye trait showed up only in males meaning all the F₂ females had red eyes, while half the males had red eyes and half had white eyes.
  • It was concluded that a fly's eye color was linked to its sex.

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