Podcast
Questions and Answers
What is the primary cause of full trisomy 21?
What is the primary cause of full trisomy 21?
- Maternal inheritance
- Hereditary transmission
- Paternal inheritance
- Meiotic nondisjunction (correct)
Approximately what percentage of full trisomy 21 cases occur due to paternal nondisjunction during spermatogenesis?
Approximately what percentage of full trisomy 21 cases occur due to paternal nondisjunction during spermatogenesis?
- 30%
- 20%
- 5% (correct)
- 10%
What is the karyotype of a male individual with full trisomy 21?
What is the karyotype of a male individual with full trisomy 21?
- 49,XY,+21
- 47,XY,+21 (correct)
- 48,XY,+21
- 46,XY,+21
In translocation trisomy 21, which chromosome is most commonly attached to chromosome 21?
In translocation trisomy 21, which chromosome is most commonly attached to chromosome 21?
What is the approximate percentage of cases where a balanced translocation is inherited from a parent in translocation trisomy 21?
What is the approximate percentage of cases where a balanced translocation is inherited from a parent in translocation trisomy 21?
What is the karyotype of an individual with a balanced Robertsonian translocation?
What is the karyotype of an individual with a balanced Robertsonian translocation?
What is the result of an unbalanced Robertsonian translocation?
What is the result of an unbalanced Robertsonian translocation?
What is the cause of mosaic trisomy 21?
What is the cause of mosaic trisomy 21?
What determines the phenotypic expression of mosaic trisomy 21?
What determines the phenotypic expression of mosaic trisomy 21?
What is the karyotype of an individual with mosaic trisomy 21?
What is the karyotype of an individual with mosaic trisomy 21?
