Principles of Psychopharmacology

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Which of the following best describes the man's initial symptoms of botulism?

He experienced double vision

What did the man do after tasting the asparagus?

He rinsed his tongue with water

What is the main topic of the field of psychopharmacology?

The effects of drugs on the nervous system

Which of the following is NOT considered a drug according to the definition provided in the text?

Neurotransmitters

Which of the following best describes the meaning of the word 'pharmakon'?

Exogenous chemical that alters cell functions

What is the main focus of psychopharmacology?

The effects of drugs on the nervous system and behavior

What are the sites of action of drugs?

Points where drugs interact with cells

Which molecules do drugs of interest to psychopharmacologists bind with in the central nervous system?

All of the above

What does the term 'affinity' refer to in the context of drug effects?

The readiness with which a drug and a molecule join together

What is one of the goals of research by drug companies?

To find chemicals with high affinities for sites of action that produce therapeutic effects

Which route of drug administration is commonly used to treat lung disorders?

Inhalation

Which route of drug administration involves placing drugs beneath the tongue?

Sublingual administration

Which route of drug administration involves injecting drugs directly into the brain or into the cerebrospinal fluid in the brain's ventricular system?

Intracerebral administration

Which route of drug administration involves absorbing drugs directly through the skin?

Topical administration

Which route of drug administration allows for the most rapid effects in the brain?

Intravenous injection

Which factor determines the rate at which a drug reaches sites of action within the brain?

Lipid solubility

Which drug is more lipid soluble, heroin or morphine?

Heroin

What is the best way to measure the effectiveness of a drug?

Plotting a dose-response curve

Which route of administration is the fastest for injecting drugs into laboratory animals?

Intravenous (IV) injection

What is the process by which drugs are absorbed, distributed within the body, metabolized, and excreted called?

Pharmacokinetics

Which section of the chapter discusses the basic principles of psychopharmacology?

The first section

Which molecules must cross several barriers to enter the body and find their way to their sites of action?

Molecules of drugs

Which of the following statements about dose-response curves is true?

The maximum effect of a drug is reached when the dose is increased.

What is the therapeutic index?

The ratio of the toxic dose to the effective dose of a drug.

Why do drugs with the same behavioral effects vary in their effectiveness?

They have different sites of action.

What is the difference between morphine and aspirin in terms of their analgesic effects?

Morphine suppresses the activity of neurons involved in pain perception, while aspirin reduces the production of a chemical involved in transmitting pain information.

Understanding Dose-Response Relationships in Drug Distribution: Test your knowledge on the relationship between drug dosage and its effects on different subjects. Explore how larger quantities are required for heavier subjects and learn about dose-response curves.

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