Dose-Response Curves

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Which effect of morphine shows the slowest shift in the dose-response curve due to tolerance?

Respiration

What happens to the margin of safety as tolerance develops in long-term use of morphine?

It decreases

Why is a higher margin of safety more desirable when using a drug with unknown potency?

It decreases the risk of overdose

Which of the following statements about the dose-response curve is true?

The dose-response curve shows that as dose increases, the effect also increases until a certain point where the effect plateaus.

Which of the following is a possible effect of opiates?

Pain relief, cough suppression, and anti-diarrhea

What is the definition of tolerance in relation to drug use?

Tolerance is a phenomenon where higher doses of a drug are required to achieve the same effect with repeated use.

Test your knowledge on dose-response curves and understand how the magnitude of an effect changes with different drug doses. Learn about the relationship between dose and effect, including the plateau point where increasing the dose no longer produces a stronger effect.

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