Dose-Response Curves
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Questions and Answers

Which effect of morphine develops tolerance at the slowest rate?

  • Euphoria
  • Liver damage
  • Respiration (correct)
  • Analgesia

What happens to the dose-response curve for euphoria as tolerance develops?

  • It shifts to the right (correct)
  • It shifts to the left
  • It remains unchanged
  • It becomes steeper

Why is a higher margin of safety more desirable when tolerance develops?

  • It reduces the risk of overdose (correct)
  • It increases the drug's potency
  • It makes the drug more effective
  • It decreases the drug's potency

Which of the following statements about the dose-response curve is true?

<p>At low doses, the effect increases until a certain point, where it plateaus. (C)</p> Signup and view all the answers

What is the main reason why the body's ability to make use of a drug becomes saturated at the plateau point?

<p>The body cannot metabolize the drug beyond a certain point. (C)</p> Signup and view all the answers

Which of the following statements about morphine is true?

<p>Morphine has different dose-response curves for different effects. (B)</p> Signup and view all the answers

Flashcards

Morphine respiration tolerance

Morphine's effect on respiration develops tolerance at a slower pace than other effects.

Euphoria tolerance shift

As tolerance to euphoria develops, the dose-response curve for euphoria shifts to the right, needing more morphine for the same effect.

Margin of safety & overdose

A higher margin of safety for a drug reduces the risk of an overdose when tolerance develops.

Dose-response curve plateau

At low doses, drug effects increase, then plateau; effect no longer increases with dose.

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Drug saturation mechanism

At plateau, body's capacity to use the drug is maxed out; metabolism can't handle any more.

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Morphine dose-response variations

Morphine has different dose-response curves for different effects (e.g., pain relief vs. euphoria).

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