Dosages and Treatments for Genital Conditions
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Questions and Answers

What is the recommended dosage of Acyclovir for a first symptomatic episode of genital herpes in adults?

  • 400 mg TID for 5 to 10 days (correct)
  • 1000 mg daily
  • 800 mg BID for 2 days
  • 200 mg TID for 5 days
  • For chronic suppressive therapy of genital herpes, which of the following dosages of Valacyclovir is correct?

  • 250 mg BID or 500 mg daily (correct)
  • 250 mg BID
  • 500 mg daily
  • 1000 mg daily if > 9 episodes per year (correct)
  • What is the recommended application schedule for Imiquimod 3.75% cream for external genital warts?

  • Every other day for 12 weeks
  • Once daily for up to 8 weeks (correct)
  • Three times per week for 16 weeks
  • Twice daily for 4 weeks
  • What is the correct dosage of Acyclovir for children with the first symptomatic herpes episode?

    <p>80 mg/kg/day divided QID for 5 to 7 days</p> Signup and view all the answers

    In pregnancy, what is the recommended dosage of Acyclovir for the first symptomatic herpes episode?

    <p>Both 200 mg 5 times daily and 400 mg TID for 5 to 10 days are correct</p> Signup and view all the answers

    What is the duration of treatment for Podofilox 0.5% solution in treating external genital warts?

    <p>3 days on, 4 days off</p> Signup and view all the answers

    For immunocompromised hosts with herpes, what is the primary recommendation?

    <p>More aggressive therapies and specialist consultation</p> Signup and view all the answers

    What is the first-line antibiotic choice for symptomatic bacterial vaginosis?

    <p>Metronidazole</p> Signup and view all the answers

    What is the usual dosage of cefixime for gonococcal urethritis in adults?

    <p>400 -800mg single dose</p> Signup and view all the answers

    Which organism is the most probable cause of acute cystitis in females?

    <p>E.coli</p> Signup and view all the answers

    What is the usual dosage of oral metronidazole for bacterial vaginosis?

    <p>500 mg BID for 7 days</p> Signup and view all the answers

    What is the usual dosage of TMP/SMX for uncomplicated UTI in females?

    <p>2 tabs BID</p> Signup and view all the answers

    What is the first-line antibiotic choice for UTI in children?

    <p>TMP/SMX</p> Signup and view all the answers

    Which antibiotic is recommended as a single-dose treatment for uncomplicated UTI in females?

    <p>Fosfomycin</p> Signup and view all the answers

    What is the usual dosage of TMP/SMX for children with UTI?

    <p>5-10 mg/kg/day trimethoprim divided q12h</p> Signup and view all the answers

    Which antibiotic is the first-line treatment for gonococcal urethritis in adults?

    <p>Ceftriaxone 250 IM dose</p> Signup and view all the answers

    Which medication is primarily used for overactive bladder management?

    <p>Mirabegron</p> Signup and view all the answers

    What is the minimum number of attempts recommended for erectile dysfunction assessment?

    <p>At least 4 attempts</p> Signup and view all the answers

    What is the main aim of bladder training for urgency incontinence?

    <p>Increase bladder capacity</p> Signup and view all the answers

    Which of the following tests is not typically performed during the initial BPH evaluation?

    <p>Serum testosterone</p> Signup and view all the answers

    Which of the following medications is least likely to cause erectile dysfunction?

    <p>Antibiotics</p> Signup and view all the answers

    What is the recommended approach for managing minimal BPH symptoms?

    <p>Active surveillance and reassurance</p> Signup and view all the answers

    What is a widely recognized non-pharmacological intervention for premature ejaculation?

    <p>Start-stop technique, pause &amp; squeeze technique</p> Signup and view all the answers

    Which medication class has been linked to an increased risk of cardiac failure in older BPH patients?

    <p>Both alpha-blockers and 5-alpha reductase inhibitors</p> Signup and view all the answers

    Which laboratory test is NOT recommended for patients on long-term PDE5 inhibitor therapy?

    <p>No testing is needed</p> Signup and view all the answers

    What is the first-line approach for managing stress urinary incontinence during pregnancy?

    <p>Pelvic floor muscle training</p> Signup and view all the answers

    Which examination component is not typically included for urinary incontinence assessment in adults?

    <p>Chest X-ray</p> Signup and view all the answers

    What are potential causes of sexual dysfunction in older adults?

    <p>All of the above</p> Signup and view all the answers

    How long should one wait to assess the effectiveness of alpha-blocker treatment for BPH?

    <p>4-8 weeks</p> Signup and view all the answers

    Which option is the first-line recommended approach for managing vaginal dryness in postmenopausal women?

    <p>Local estrogen therapy</p> Signup and view all the answers

    Which of the following is a potential complication of untreated long-term bladder outlet obstruction?

    <p>All of the above</p> Signup and view all the answers

    Which lifestyle modification is known to improve erectile function?

    <p>All of the above</p> Signup and view all the answers

    What is the suggested initial response for children exhibiting inappropriate sexual behaviors?

    <p>Psychoeducation and behavioral interventions</p> Signup and view all the answers

    What is the primary focus of pelvic floor muscle exercises in managing stress urinary incontinence?

    <p>Strengthen pelvic floor muscles</p> Signup and view all the answers

    Which is NOT a common side effect of alprostadil injections?

    <p>Dizziness</p> Signup and view all the answers

    What dietary change is suggested for managing urinary symptoms?

    <p>Reducing alcohol consumption</p> Signup and view all the answers

    What is a significant risk when prescribing alpha-blockers?

    <p>Potential orthostatic hypotension</p> Signup and view all the answers

    Which effect do antimuscarinic medications have in BPH management?

    <p>They expand bladder capacity</p> Signup and view all the answers

    Which is a common side effect of anticholinergic medications for BPH?

    <p>Dry mouth and constipation</p> Signup and view all the answers

    When determining treatment options, what should be considered?

    <p>Severity of symptoms and complications</p> Signup and view all the answers

    What is the freezing margin recommended beyond the wart diameter in cryotherapy?

    <p>1-2 mm</p> Signup and view all the answers

    What is the risk of vertical transmission when a primary herpes outbreak occurs at delivery?

    <p>30-40%</p> Signup and view all the answers

    How long should Imiquimod 5% cream be washed off after application?

    <p>6-10 hours</p> Signup and view all the answers

    What is the duration of treatment for neonatal herpes affecting only skin, eye, and mucous membranes?

    <p>14 days</p> Signup and view all the answers

    How often should chronic suppressive therapy for herpes be reassessed?

    <p>Every 6-12 months</p> Signup and view all the answers

    By what percentage is recurrent genital herpes reduced with suppressive therapy?

    <p>70-80%</p> Signup and view all the answers

    What is the maximum treatment area recommended for provider-administered therapies?

    <p>≤ 10 cm²</p> Signup and view all the answers

    Which antibiotic is identified as the first-line treatment for symptomatic UTI in nursing home residents?

    <p>TMP/SMX 1DS BID x 7 days</p> Signup and view all the answers

    What is the usual dosage of Nitrofurantoin prescribed for recurrent cystitis in females?

    <p>50-100 mg QID</p> Signup and view all the answers

    Which of the following is a second-line antibiotic for treating recurrent cystitis in females?

    <p>Norfloxacin</p> Signup and view all the answers

    What is the typical dosage range of Cephalexin prescribed for UTI in children?

    <p>25-50 mg/kg/day divided q6h</p> Signup and view all the answers

    Which organism is a common cause of symptomatic UTI in nursing home residents?

    <p>E.coli</p> Signup and view all the answers

    What is the usual dosage of Trimethoprim for UTI treatment in nursing home residents?

    <p>100 mg BID</p> Signup and view all the answers

    Which antibiotic is suggested as a third-line choice for UTI in children?

    <p>Cefixime</p> Signup and view all the answers

    What is the usual dosage of Ciprofloxacin for UTI in nursing home residents?

    <p>500 mg (extended release) once daily</p> Signup and view all the answers

    Which antibiotic is the first-line choice for early relapse of cystitis in females?

    <p>TMP/SMX</p> Signup and view all the answers

    What is the primary goal of bladder training for urgency incontinence?

    <p>Increase bladder capacity</p> Signup and view all the answers

    Which medication class is associated with an increased risk of new cardiac failure in patients over 66 years with BPH?

    <p>Both B and C</p> Signup and view all the answers

    What is the recommended duration of treatment with alpha-blockers before assessing their effectiveness in BPH?

    <p>4-8 weeks</p> Signup and view all the answers

    Which of the following is not typically included in the initial laboratory tests for BPH evaluation?

    <p>Serum testosterone</p> Signup and view all the answers

    What is the recommended approach for patients with minimal BPH symptoms?

    <p>Reassurance and active surveillance</p> Signup and view all the answers

    Which type of urinary incontinence commonly occurs due to increased abdominal pressure during activities such as sneezing or exercise?

    <p>Stress incontinence</p> Signup and view all the answers

    What is the primary goal of bladder training in patients with urgency incontinence?

    <p>Delay urination and improve bladder control</p> Signup and view all the answers

    Which medication class is primarily used for treating urgency urinary incontinence?

    <p>Antimuscarinics</p> Signup and view all the answers

    What should be monitored closely when prescribing antimuscarinics to elderly patients?

    <p>Risk of cognitive decline or dementia</p> Signup and view all the answers

    Which lifestyle change is NOT recommended for individuals managing urinary incontinence?

    <p>Increased alcohol consumption</p> Signup and view all the answers

    For pelvic floor muscle exercises to be effective, what is the recommended time frame to see significant improvement?

    <p>6-8 weeks</p> Signup and view all the answers

    Which type of urinary incontinence is characterized by an inability to sense a full bladder, commonly found in patients with neurological issues?

    <p>Overflow incontinence</p> Signup and view all the answers

    Which statement best describes mixed incontinence?

    <p>Involves both stress incontinence and urgency incontinence</p> Signup and view all the answers

    How long should a patient typically wait to evaluate the effectiveness of antimuscarinic medications for urgency incontinence?

    <p>4-8 weeks</p> Signup and view all the answers

    What common factor contributes to the prevalence of urinary incontinence in older females?

    <p>Hormonal changes post-menopause</p> Signup and view all the answers

    What is the minimum number of doses required per week for PrEP to be effective in MSM/TGW?

    <p>≥4 doses/week</p> Signup and view all the answers

    Which of the following is a contraindication for PrEP?

    <p>Positive HIV test</p> Signup and view all the answers

    How often should STI screening occur while on PrEP?

    <p>Every 3 months</p> Signup and view all the answers

    Which test is recommended to monitor kidney function in patients on PrEP?

    <p>Serum creatinine and eGFR</p> Signup and view all the answers

    What should be done if a patient on PrEP shows symptoms of acute HIV infection?

    <p>Defer PrEP and repeat HIV test in 1-3 weeks</p> Signup and view all the answers

    Which population is DESCOVY FDA-approved for as PrEP?

    <p>MSM/TGW only</p> Signup and view all the answers

    What is the recommended frequency for monitoring lipid panels with FTC/TAF (DESCOVY)?

    <p>Every 12 months</p> Signup and view all the answers

    Which drug interaction requires monitoring when prescribing TRUVADA for PrEP?

    <p>NSAIDs</p> Signup and view all the answers

    What is the potential effect of TRUVADA on bone mineral density?

    <p>Decrease</p> Signup and view all the answers

    What action should be taken for a patient with a recent high-risk exposure who is eligible for PrEP?

    <p>Refer for nPEP</p> Signup and view all the answers

    What modification in dosing may be recommended for individuals who experience more than 9 episodes of genital herpes per year?

    <p>Increase to 500 mg daily or 1000 mg daily</p> Signup and view all the answers

    Which of the following best describes the recommended treatment duration for Imiquimod 3.75% cream on external genital warts?

    <p>Once daily for up to 8 weeks</p> Signup and view all the answers

    For a child experiencing a first symptomatic episode of herpes, what is the correct dosing of Acyclovir?

    <p>80 mg/kg/day divided QID for 5 to 7 days</p> Signup and view all the answers

    What is the correct dosage of Acyclovir for pregnant individuals experiencing their first symptomatic episode of herpes?

    <p>200 mg QID or 400 mg TID</p> Signup and view all the answers

    During treatment of external genital warts, what is the suggested duration for Podofilox 0.5% solution?

    <p>3 days on, 4 days off</p> Signup and view all the answers

    What is the primary recommendation for managing herpes in immunocompromised hosts?

    <p>More aggressive therapies and consultation with a specialist</p> Signup and view all the answers

    What is the maximum duration for Sinecatechins 10% ointment treatment?

    <p>Up to 16 weeks</p> Signup and view all the answers

    What is a potential complication of long-term bladder outlet obstruction in BPH?

    <p>Hydronephrosis</p> Signup and view all the answers

    What is the first-line recommended approach for stress urinary incontinence during pregnancy?

    <p>Pelvic floor muscle training</p> Signup and view all the answers

    Which medication is primarily indicated for urgency urinary incontinence management?

    <p>Mirabegron</p> Signup and view all the answers

    What is the recommended time frame to wait before evaluating the effectiveness of pelvic floor muscle exercises?

    <p>6-8 weeks</p> Signup and view all the answers

    Which of the following lifestyle changes is advised against for individuals managing urgency urinary incontinence?

    <p>Increased alcohol consumption</p> Signup and view all the answers

    What is the primary objective of bladder training in patients with urgency incontinence?

    <p>Increase bladder capacity</p> Signup and view all the answers

    Which class of medications may heighten the risk of new cardiac failure in older patients with BPH?

    <p>Alpha-blockers</p> Signup and view all the answers

    Which first-line method is recommended for stress urinary incontinence during pregnancy?

    <p>Pelvic floor muscle training</p> Signup and view all the answers

    Which of the following components is not typically assessed in a physical examination for urinary incontinence?

    <p>Chest X-ray</p> Signup and view all the answers

    What is the advised duration for treatment with alpha-blockers before evaluating their efficacy in BPH?

    <p>4-8 weeks</p> Signup and view all the answers

    Which complication is associated with prolonged bladder outlet obstruction in BPH?

    <p>All of the above</p> Signup and view all the answers

    What is the recommended strategy for managing patients with minimal symptoms of BPH?

    <p>Reassurance and active surveillance</p> Signup and view all the answers

    Which type of urinary incontinence is primarily caused by involuntary contractions of the bladder muscle?

    <p>Urgency incontinence</p> Signup and view all the answers

    What is the typical first-line treatment for stress urinary incontinence?

    <p>Pelvic floor muscle exercises</p> Signup and view all the answers

    Which non-pharmacological approach is least effective for managing urgency urinary incontinence?

    <p>Botulinum toxin injections</p> Signup and view all the answers

    Which demographic is more likely to experience urinary incontinence?

    <p>Older females</p> Signup and view all the answers

    How long does it typically take to notice benefits from antimuscarinic medications in urgency incontinence?

    <p>4-8 weeks</p> Signup and view all the answers

    Which type of incontinence is characterized by involuntary leakage of urine associated with physical activity?

    <p>Stress incontinence</p> Signup and view all the answers

    What is a common side effect of antimuscarinic medications that may affect elderly patients?

    <p>Diminished cognitive function</p> Signup and view all the answers

    What lifestyle modification is generally recommended to help improve outcomes for urinary incontinence?

    <p>Caffeine reduction</p> Signup and view all the answers

    Which of the following types of urinary incontinence may occur due to bladder overflow?

    <p>Overflow incontinence</p> Signup and view all the answers

    Which test is generally not indicated for men when evaluating urinary conditions?

    <p>PSA test</p> Signup and view all the answers

    What is the minimum number of doses of PrEP required per week for it to be effective in MSM/TGW?

    <p>≥4 doses/week</p> Signup and view all the answers

    Which condition is contraindicated for the use of PrEP?

    <p>Positive HIV test</p> Signup and view all the answers

    What is the recommended frequency for STI screening for an individual on PrEP?

    <p>Every 3 months</p> Signup and view all the answers

    Which test is important to monitor kidney function in patients on PrEP?

    <p>Serum creatinine and eGFR</p> Signup and view all the answers

    How often should pregnancy testing be conducted in individuals using PrEP?

    <p>Every 3 months</p> Signup and view all the answers

    What should be done if a patient on PrEP shows signs of acute HIV infection?

    <p>Defer PrEP and repeat HIV test in 1-3 weeks</p> Signup and view all the answers

    Which drug interaction should be monitored when prescribing TRUVADA for PrEP?

    <p>NSAIDs</p> Signup and view all the answers

    What is the recommended frequency for lipid panel monitoring with FTC/TAF (DESCOVY)?

    <p>Every 12 months</p> Signup and view all the answers

    Which of the following is NOT recommended for monitoring individuals on FTC/TAF (DESCOVY)?

    <p>Pregnancy testing every 6 months</p> Signup and view all the answers

    What is the recommended action if a patient using PrEP shows symptoms indicative of acute HIV infection?

    <p>Defer PrEP and repeat HIV test in 1-3 weeks</p> Signup and view all the answers

    How long should PrEP be continued after the last potential HIV exposure in heterosexual individuals?

    <p>28 days</p> Signup and view all the answers

    Which of the following is NOT a standard baseline investigation for initiating PrEP?

    <p>CD4 count</p> Signup and view all the answers

    What is the recommended frequency for urinalysis for individuals on PrEP?

    <p>Optional, based on expert opinion</p> Signup and view all the answers

    What is the correct interval for cryotherapy applications?

    <p>Every 1-2 weeks</p> Signup and view all the answers

    What is the recommended timing for podophyllin resin removal after application?

    <p>3-4 hours</p> Signup and view all the answers

    By what percentage does suppressive therapy reduce recurrent genital herpes?

    <p>70-80%</p> Signup and view all the answers

    When using Sinecatechins ointment, what amount should be applied?

    <p>0.5 cm</p> Signup and view all the answers

    What is the first-line treatment for symptomatic bacterial vaginosis?

    <p>Metronidazole</p> Signup and view all the answers

    What is the single-dose treatment recommended for uncomplicated UTI in females?

    <p>Fosfomycin</p> Signup and view all the answers

    For gonococcal urethritis in adults, what is the usual dosage of cefixime?

    <p>400 mg single dose</p> Signup and view all the answers

    Which of these organisms is the most common cause of acute cystitis in females?

    <p>E. coli</p> Signup and view all the answers

    What is the usual dosage of TMP/SMX for uncomplicated UTI in children?

    <p>5-10 mg/kg/day trimethoprim divided q12h</p> Signup and view all the answers

    What is the recommended usual dosage of oral metronidazole for bacterial vaginosis?

    <p>500 mg BID for 7 days</p> Signup and view all the answers

    What is the usual dosage of ceftriaxone IM for gonococcal urethritis in children under 12 years?

    <p>TMP/SMX</p> Signup and view all the answers

    What is the usual dosage of Trimethoprim for uncomplicated UTI in females?

    <p>200 mg once daily</p> Signup and view all the answers

    What is the HIRI-MSM score threshold to indicate a 2% risk of incident HIV?

    <p>≥10</p> Signup and view all the answers

    What is the appropriate follow-up period for prescribing PrEP after the initial month?

    <p>3 months</p> Signup and view all the answers

    Which of the following populations has the highest incidence of HIV diagnoses in Canada?

    <p>Indigenous peoples</p> Signup and view all the answers

    Which medication is recommended for individuals with a history of fractures or osteoporosis?

    <p>DESCOVY</p> Signup and view all the answers

    What percentage of HIV cases in Saskatchewan is attributed to people who inject drugs?

    <p>50%</p> Signup and view all the answers

    How frequently should HIV testing be conducted after starting PrEP?

    <p>Every 3 months</p> Signup and view all the answers

    Which population is specifically recommended for screening and treating asymptomatic bacteriuria?

    <p>During pregnancy and/or pre-operative genitourinary procedures</p> Signup and view all the answers

    Which antibiotic is recognized as the first-line treatment for asymptomatic bacteriuria when necessary?

    <p>Nitrofurantoin</p> Signup and view all the answers

    Which of the following is NOT required as part of the baseline investigations for PrEP?

    <p>Chest X-ray</p> Signup and view all the answers

    What is the recommended daily dosing for TRUVADA when used as PrEP?

    <p>1 tablet once daily</p> Signup and view all the answers

    What is the common dosage of TMP/SMX when treating asymptomatic bacteriuria?

    <p>2 tabs BID</p> Signup and view all the answers

    What is a common transient side effect of PrEP?

    <p>Headache</p> Signup and view all the answers

    Which organism accounts for the majority (60-70%) of asymptomatic bacteriuria cases?

    <p>E.coli</p> Signup and view all the answers

    In the on-demand "2-1-1" method of PrEP, how many tablets are taken 2-24 hours before sexual activity?

    <p>2 tablets</p> Signup and view all the answers

    What is the standard dosage of Fosfomycin for asymptomatic bacteriuria treatment?

    <p>3 g dissolved in 1/2 cup of cold water once</p> Signup and view all the answers

    What is the first-line antibiotic recommended for acute cystitis in pregnant women?

    <p>Cephalexin</p> Signup and view all the answers

    How is Nitrofurantoin typically dosed for acute cystitis in pregnant women?

    <p>50-100 mg QID</p> Signup and view all the answers

    Which antibiotic can be used as a second-line treatment for acute cystitis affecting pregnant women?

    <p>Amoxicillin</p> Signup and view all the answers

    What is the usual dosage of TMP/SMX for acute cystitis in pregnant women?

    <p>1 DS tab BID</p> Signup and view all the answers

    Which organisms are frequently implicated in causing acute cystitis in pregnant women?

    <p>E.coli, Klebsiella, Proteus, Enterococci</p> Signup and view all the answers

    Study Notes

    • Acyclovir (genital herpes, adults): 400 mg TID for 5 to 10 days.
    • Valacyclovir (chronic suppressive therapy of genital herpes): 250 mg BID or 500 mg daily; 1000 mg daily if >9 episodes per year.
    • Imiquimod 3.75% cream (external genital warts): Once daily for up to 8 weeks.
    • Acyclovir (genital herpes, children): 80 mg/kg/day divided QID for 5 to 7 days.
    • Acyclovir (genital herpes, pregnancy): 200 mg 5 times daily or 400 mg TID for 5 to 10 days (both a and b are correct).
    • Podofilox 0.5% solution (external genital warts): 3 days on, 4 days off.

    Other Treatments and Dosages

    • Sinecatechins 10% ointment (genital warts): Up to 16 weeks.
    • Acyclovir (acute recurrent herpes, children): Either 200 mg 5 times daily or 400 mg TID for 5 days.
    • Podofilox treatment cycles: Maximum of 4 cycles.
    • TCA treatment (genital warts): 80-90% in ethyl alcohol.
    • Valacyclovir (acute recurrent herpes): 500 mg BID for 3 days or 1000 mg daily for 5 days.
    • Famciclovir (chronic suppressive therapy): 250 mg BID.
    • Cryotherapy treatment (genital warts): Maximum 8 weeks.
    • EMLA cream (before TCA treatment): 10-20 minutes.

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    Description

    Test your knowledge on recommended dosages and treatments for various genital conditions, including genital herpes and warts. This quiz covers the specific dosages for adults, children, and pregnant individuals, as well as the duration of treatment for different medications. Challenge yourself to recall essential information about antiviral and topical treatments.

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