Dopamine Pathways and Neuroleptic Side Effects

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10 Questions

Typical antipsychotics, such as Haloperidol, can cause extra pyramidal side effects due to dopamine receptor blockade in the nigrostriatal pathway.

True

Atypical antipsychotics, such as Olanzapine, are less effective against positive symptoms of schizophrenia compared to typical antipsychotics.

False

Neuroleptic malignant syndrome (NMS) is a rare side effect of antipsychotic medication, occurring in approximately 0.01% of patients.

False

Dantrolene is a specific antidote for Neuroleptic malignant syndrome (NMS).

False

Atypical antipsychotics, such as Clozapine, are associated with a higher risk of Neuroleptic malignant syndrome (NMS) compared to typical antipsychotics.

False

Chlorpromazine is a type of butyrophenone.

False

Typical antipsychotics work by inhibiting D1 receptors.

False

Flupenthixol is a type of thioxanthene.

True

Sulpride is a type of indole derivative.

False

Haloperidol is a type of phenothiazine.

False

This quiz covers the effects of dopamine pathway blockage, including negative symptoms, extrapyramidal symptoms, hyperprolactinaemia, and tardive dyskinesia. It's essential for understanding neuroleptic induced deficiencies and side effects.

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