Questions and Answers
What is the trade name for Dobutamine?
What is the mechanism of action (M.O.A.) of Dobutamine?
Sympathetic agonist acting primarily on the beta 1 receptors with little alpha effect.
What conditions are indicated for the use of Dobutamine?
CHF, cardiogenic shock with stable pressure, hypovolemia if fluid resuscitation is underway.
What is a contraindication for using Dobutamine?
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What is the dosage and route for administering Dobutamine?
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List some side effects of Dobutamine.
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What special considerations should be taken into account when using Dobutamine?
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What is the classification of Dobutamine?
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What is the trade name for Dopamine?
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What is the classification of Dopamine?
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What is the mechanism of action (M.O.A.) of Dopamine?
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What conditions are indicated for the use of Dopamine?
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What is a contraindication for using Dopamine?
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What is the dosage and route for administering Dopamine?
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List some side effects of Dopamine.
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What special considerations should be taken into account when using Dopamine?
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Study Notes
Dobutamine Overview
- Trade name: Dobutrex
- Acts primarily on beta 1 receptors with minimal alpha effects
- Indicated for congestive heart failure (CHF) and cardiogenic shock with stable pressure
- Contraindicated in patients with systolic blood pressure less than 100
- Administered by continuous drip at a dosage of 2-20 mcg/kg/min using a concentration of 500 mcg/mL
- Common side effects include nervousness, headaches, hypertension, and dysrhythmias
- Effectiveness may be reduced in patients taking beta-blockers; monitor blood pressure closely
- Classified as a sympathomimetic agent
Dopamine Overview
- Trade name: Intropin
- Functions as a sympathetic agonist and is a precursor of norepinephrine
- Acts on alpha, beta 1, and dopaminergic receptors; promotes positive inotropic effect while minimizing oxygen demand
- Primarily indicated for significant hypotension not caused by hypovolemia, especially when fluid resuscitation is in progress
- Contraindicated in patients with pheochromocytoma due to potential for hypertension
- Administered only as an IV drip with initial dosage of 2-5 mcg/kg/min, titrated based on blood pressure response; concentrated at 1600 mcg/mL
- Side effects include nervousness, headaches, and potential dysrhythmias; all effects are dose-dependent
- Special considerations include deactivation by alkaline solutions and the potential to worsen supraventricular tachycardia (SVT) at higher doses
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Description
This quiz focuses on the key aspects of dopamine and dobutamine, including the trade name, mechanism of action, and indications for use. Perfect for medical students and professionals looking to reinforce their knowledge about these vital drugs.
