Donepezil Drug Interactions Quiz
12 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main concern with using memantine concurrently with other drugs?

  • Increased neuromuscular blockade and prolonged respiratory depression
  • Decreased anti-AChE effects of neostigmine or pyridostigmine
  • Interference with anticholinergic activity
  • Accumulation of the drug leading to increased adverse effects (correct)

    • Which of the following drug combinations should be avoided due to the risk of synergistic effects?

  • Neostigmine and aminoglycoside antibiotics
  • Cholinomimetics and other cholinesterase inhibitors (correct)
  • Pyridostigmine and corticosteroids
  • Memantine and succinylcholine

    • What is the recommended course of action if a patient is taking corticosteroids concurrently with neostigmine or pyridostigmine?

  • Increase the dose of neostigmine or pyridostigmine
  • Avoid concurrent use or provide respiratory support as needed (correct)
  • Discontinue the corticosteroids immediately
  • Monitor the patient for decreased anti-AChE effects

    • What is the primary concern with using magnesium concurrently with neostigmine or pyridostigmine?

    <p>Magnesium's direct depressant effect on skeletal muscle may antagonize the beneficial effects of the anti-AChE drugs</p> Signup and view all the answers

    What is the recommended course of action if a patient is taking local or general anesthetics, or antiarrhythmic drugs, concurrently with neostigmine?

    <p>Increase the dose of neostigmine</p> Signup and view all the answers

    What is the primary concern with using rivastigmine concurrently with anticholinergic drugs?

    <p>Rivastigmine may interfere with the activity of the anticholinergic drugs</p> Signup and view all the answers

    What is the effect of donepezil on anticholinergics?

    <p>Donepezil antagonizes the activity of anticholinergics</p> Signup and view all the answers

    What is the recommended action when donepezil is administered with bethanechol or succinylcholine?

    <p>Reduce the bethanechol dose if they must be given concurrently</p> Signup and view all the answers

    What is the potential effect of donepezil on drugs metabolized by CYP450 2D6 and 3A4 isoenzymes, such as ketoconazole and quinidine?

    <p>Donepezil may inhibit the metabolism of these drugs</p> Signup and view all the answers

    Which of the following statements regarding the interaction between galantamine and cimetidine is correct?

    <p>Cimetidine increases the bioavailability of galantamine by 16%</p> Signup and view all the answers

    What is the effect of paroxetine on galantamine?

    <p>Paroxetine increases the bioavailability of galantamine by 40%</p> Signup and view all the answers

    What is the recommended action when memantine is administered with drugs, diets, or clinical states that make urine alkaline?

    <p>Avoid concurrent use or monitor for increased drug effects</p> Signup and view all the answers

    More Like This

    Donepezil Dosage and Nursing Implications Quiz
    30 questions

    Donepezil Nursing Assessment Quiz & Flashcards

    UserFriendlyIntelligence avatar
    UserFriendlyIntelligence
    Donepezil Drug Interactions Quiz
    12 questions

    Donepezil Drug Interactions Quiz

    TopSerpentine5393 avatar
    TopSerpentine5393
    Donepezil (Aricept) Flashcards
    10 questions

    Donepezil (Aricept) Flashcards

    WholesomeVibrance avatar
    WholesomeVibrance
    Donepezil (Aricept) Flashcards
    10 questions

    Donepezil (Aricept) Flashcards

    AvidFoxglove avatar
    AvidFoxglove
    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser