Dolly the Clone: The Story of Cloning
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Questions and Answers

What was the primary source of the nucleus used to create Dolly?

  • A male Finn Dorsett sheep
  • A female Finn Dorsett sheep's mammary gland cell (correct)
  • An undifferentiated embryonic cell
  • A female Scottish blackface ewe

Which of the following describes Dolly's parentage?

  • Dolly was a hybrid of two distinct sheep breeds.
  • Dolly inherited traits from the Scottish blackface ewe.
  • Dolly was cloned from the egg of a Finn Dorsett sheep.
  • Dolly had no genetic connection to the Scottish blackface ewe. (correct)

What was unique about Dolly in the context of animal cloning history?

  • Dolly was cloned from a woolly mammoth.
  • Dolly was the first cloned animal to survive in the wild.
  • Dolly was the first cloned animal to reproduce.
  • Dolly was the first mammal to be cloned successfully. (correct)

What happened to the egg after the nucleus was removed from it during Dolly's cloning process?

<p>The nucleus from a Finn Dorsett cell was inserted into it. (D)</p> Signup and view all the answers

What was one of the significant outcomes after Dolly's birth?

<p>Cloned animals began exhibiting genetic disorders. (B)</p> Signup and view all the answers

On what date did Dolly pass away?

<p>14th February 2003 (C)</p> Signup and view all the answers

Why did Dolly not exhibit any characteristics of the Scottish blackface ewe?

<p>The nucleus from the Scottish blackface was not retained. (D)</p> Signup and view all the answers

What disease ultimately caused Dolly's death?

<p>A respiratory disease (C)</p> Signup and view all the answers

What was the method of reproduction for Dolly after she was cloned?

<p>She reproduced normally through sexual means. (B)</p> Signup and view all the answers

Which of the following statements is true regarding the cloning process of animals after Dolly?

<p>Most cloned mammals did not survive beyond infancy. (D)</p> Signup and view all the answers

Study Notes

Overview of Cloning

  • Cloning produces exact copies of cells, tissues, or entire organisms.
  • Ian Wilmut and colleagues at the Roslin Institute in Edinburgh successfully cloned the first animal.

Dolly the Sheep

  • Dolly, born on July 5, 1996, was the first mammal cloned from an adult somatic cell.
  • The cloning process involved collecting a cell from the mammary gland of a Finn Dorsett sheep.
  • An egg was sourced from a Scottish blackface ewe, and its nucleus was removed.
  • The nucleus from the Finn Dorsett sheep's cell was inserted into the enucleated egg.
  • The modified egg was implanted in the Scottish blackface ewe, leading to Dolly's birth.

Genetic Identity and Characteristics

  • Dolly was genetically identical to the Finn Dorsett sheep, the source of the nucleus.
  • She did not exhibit traits from the Scottish blackface ewe since her nuclear DNA originated entirely from the Finn Dorsett.

Life and Legacy

  • Dolly lived a healthy life, producing several offspring through normal sexual reproduction.
  • She passed away on February 14, 2003, due to a lung disease.
  • Dolly's creation sparked numerous cloning attempts in mammals, but many clones face lethal conditions or severe abnormalities.

Broader Implications

  • The cloning of Dolly raised ethical questions and concerns regarding cloning practices.
  • Since Dolly, many cloned animals do not survive to birth or lead healthy lives, highlighting the challenges of cloning technology.

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Description

This quiz will test your knowledge about Dolly, the first mammal to be cloned, and the process of cloning itself. Learn about the scientific background and key facts surrounding Dolly’s birth and her significance in the field of genetic research.

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