Podcast
Questions and Answers
What type of sugar is found in DNA?
What type of sugar is found in DNA?
- Fructose
- Ribose
- Glucose
- Deoxyribose (correct)
Which enzyme is responsible for unwinding the DNA double helix during replication?
Which enzyme is responsible for unwinding the DNA double helix during replication?
- Ligase
- Topoisomerase
- DNA polymerase
- Helicase (correct)
What is the role of RNA during DNA replication?
What is the role of RNA during DNA replication?
- To provide a primer for DNA synthesis (correct)
- To stabilize the DNA structure
- To directly synthesize DNA strands
- To transport amino acids to ribosomes
Which direction does DNA polymerase add nucleotides during DNA synthesis?
Which direction does DNA polymerase add nucleotides during DNA synthesis?
What is the function of primase in DNA replication?
What is the function of primase in DNA replication?
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Study Notes
DNA Structure and Function
- DNA, or deoxyribonucleic acid, is the molecule that carries genetic information.
- Its structure consists of a sugar-phosphate backbone and nitrogenous bases (adenine, thymine, cytosine, guanine).
- Deoxyribose is the sugar component of DNA, contributing to its name.
DNA Replication Process
- Replication begins with unwinding the DNA double helix, a process facilitated by an enzyme known as helicase.
- Leading strand synthesis proceeds continuously, while the lagging strand is synthesized in short segments called Okazaki fragments.
- RNA primase synthesizes a short RNA primer, allowing DNA polymerase to begin elongation of the new DNA strand.
Key Enzymes Involved
- Topoisomerase alleviates the strain ahead of the replication fork caused by unwinding.
- DNA polymerase is responsible for adding nucleotides to the growing DNA strand.
- RNAse degrades the RNA primers once DNA synthesis is underway, allowing for complete DNA strand formation.
Important Concepts
- The directionality of DNA strands is indicated as 5' to 3', a crucial factor during replication.
- Each strand of DNA serves as a template for the formation of a new complementary strand.
- Accurate DNA replication is critical for maintaining genetic consistency in cell division and organism growth.
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