DNA Structure and Properties

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Questions and Answers

What serves as a template for the new DNA strand in replication?

  • DNA polymerase
  • Existing DNA strand (correct)
  • RNA polymerase
  • Topoisomerase

In the context of DNA replication, what is the role of topoisomerase?

  • Unwinding the DNA helix (correct)
  • Extending the primer
  • Adding nucleotides to the new strand
  • Making the primer

Which of the following is NOT a method of classical plant breeding?

  • Genetic engineering (correct)
  • Pure-line selection
  • Selective Breeding
  • Crossbreeding

What is the primary objective of pure-line selection in plant breeding?

<p>To establish a homogenous breed with a specific trait (D)</p> Signup and view all the answers

What is the significance of the Meselson-Stahl experiment?

<p>It demonstrated the semi-conservative nature of DNA replication. (B)</p> Signup and view all the answers

What is the primary difference between selective breeding and crossbreeding?

<p>Selective breeding aims to establish a breed with a specific trait, while crossbreeding focuses on creating new traits. (B)</p> Signup and view all the answers

Which of these is NOT a characteristic of DNA replication?

<p>It starts at a single point in the DNA molecule. (C)</p> Signup and view all the answers

Which method of classical plant breeding is most suitable for developing a variety with a high yield?

<p>Mass selection (A)</p> Signup and view all the answers

Which of the following is NOT a key step in the abiotic synthesis of life, as outlined in the provided text?

<p>The formation of complex carbohydrates and lipids (A)</p> Signup and view all the answers

What did the Miller-Urey experiment demonstrate about the early Earth's atmosphere?

<p>Organic molecules could have been formed abiotically. (B)</p> Signup and view all the answers

What is the significance of the discovery of the Murchison meteorite?

<p>It was a source of organic compounds on early Earth. (A)</p> Signup and view all the answers

What is a protocell?

<p>A fluid-filled compartment enclosed by a membrane-like structure. (D)</p> Signup and view all the answers

What is the significance of montmorillonite particles in the context of protocells?

<p>They can be absorbed by protocells, potentially carrying RNA. (A)</p> Signup and view all the answers

What is the significance of the 2009 study on the abiotic synthesis of RNA monomers?

<p>It suggests that RNA could have been the first genetic material. (C)</p> Signup and view all the answers

What is the main difference between the hypothesized early atmosphere and the current atmosphere?

<p>The early atmosphere was a reducing atmosphere. (A)</p> Signup and view all the answers

What does the term "abiotic synthesis" refer to?

<p>The spontaneous formation of complex organic molecules from simpler inorganic molecules. (A)</p> Signup and view all the answers

In what geological period did the first birds evolve?

<p>Jurassic (A)</p> Signup and view all the answers

Which of the following evolutionary changes occurred in very late cynodonts and early mammals?

<p>The loss of the original articular-quadrate hinge. (D)</p> Signup and view all the answers

What is the primary characteristic that distinguishes the Phanerozoic Eon?

<p>The presence of abundant fossils. (B)</p> Signup and view all the answers

What are the two main categories of developmental changes that can result in morphological evolution?

<p>Changes in Spatial Pattern and Changes in Rate and Timing (D)</p> Signup and view all the answers

When did the first dinosaurs appear?

<p>Triassic Period (D)</p> Signup and view all the answers

During which period did the extinction of dinosaurs occur?

<p>Cretaceous (A)</p> Signup and view all the answers

What is the name of the condition where sexually mature organisms retain juvenile features from their ancestral species due to accelerated reproductive organ development?

<p>Paedomorphosis (D)</p> Signup and view all the answers

What is the role of Hox genes in developmental changes?

<p>Hox genes control the placement and spatial organization of body parts. (A)</p> Signup and view all the answers

Among the following, what is the shortest unit of geological time?

<p>Epoch (A)</p> Signup and view all the answers

How does the concept of adaptive radiation relate to changes in developmental genes?

<p>Adaptive radiation is a process of rapid speciation driven by changes in developmental genes. (D)</p> Signup and view all the answers

What is the main difference between late cynodonts and very late cynodonts?

<p>Very late cynodonts lost the original articular-quadrate hinge, while late cynodonts retained it. (A)</p> Signup and view all the answers

What is the main idea behind the statement "Adaptive evolution of both new and existing genes may have played a key role in shaping the great diversity of life"?

<p>Natural selection acts on existing genetic variations. (C)</p> Signup and view all the answers

What were the articular and quadrate bones in cynodonts adapted to do in mammals?

<p>They became part of the ear. (A)</p> Signup and view all the answers

What is an example of a developmental change that could contribute to the evolution of a new species?

<p>A change in the timing of development of limbs in a mammal. (D)</p> Signup and view all the answers

Which of the following periods is associated with the rise of the first primates?

<p>Cretaceous (C)</p> Signup and view all the answers

How can changes in developmental genes drive adaptive radiations?

<p>By modifying the expression patterns of existing genes, leading to changes in morphology and behavior. (D)</p> Signup and view all the answers

Which of the following statements is TRUE about the geological time scale?

<p>It is organized into hierarchical units. (D)</p> Signup and view all the answers

What is the name of the geological era in which modern humans evolved?

<p>Cenozoic (D)</p> Signup and view all the answers

Which of the following is NOT a characteristic of paedomorphosis?

<p>Slower development of reproductive organs. (C)</p> Signup and view all the answers

Which of the following periods is known as the "age of invertebrates"?

<p>Cambrian (C)</p> Signup and view all the answers

What is the name of the geological period that is characterized by the evolution of the first mammals?

<p>Triassic (A)</p> Signup and view all the answers

What is the main characteristic that distinguishes the Mesozoic Era?

<p>The reign of dinosaurs. (A)</p> Signup and view all the answers

Which of the following geological periods saw the first flowering plants evolve?

<p>Cretaceous (C)</p> Signup and view all the answers

Which of the following methods utilizes artificial insemination as a technique?

<p>Artificial Reproductive Technologies (B)</p> Signup and view all the answers

What is the primary goal of cross-breeding in plant breeding?

<p>To create new varieties with desirable traits. (A)</p> Signup and view all the answers

In what breeding method are the protoplasts of different plants fused together?

<p>Somatic Hybridization (D)</p> Signup and view all the answers

Which breeding method specifically focuses on the selection and propagation of superior hybrid plants that cannot reproduce sexually?

<p>Clonal Selection (A)</p> Signup and view all the answers

What is the defining characteristic of genetic engineering in contrast to traditional breeding methods?

<p>It directly manipulates the genetic makeup of organisms. (C)</p> Signup and view all the answers

Which of the following is NOT a mechanism of evolution?

<p>Cellular respiration (C)</p> Signup and view all the answers

What is the primary driving force behind natural selection?

<p>The ability of individuals to survive and reproduce (C)</p> Signup and view all the answers

In the context of evolution, what is the significance of variation within a population?

<p>All of the above (D)</p> Signup and view all the answers

What is the relationship between natural selection and adaptation?

<p>Adaptation is the outcome of natural selection (C)</p> Signup and view all the answers

How do the concepts of 'overproduction' and 'variation' contribute to natural selection?

<p>Overproduction generates a surplus of individuals, some with traits better suited to the environment (B)</p> Signup and view all the answers

Which of the following scenarios best exemplifies artificial selection?

<p>A farmer selectively breeds chickens for larger egg production (D)</p> Signup and view all the answers

Why is it important to understand the difference between natural and artificial selection?

<p>All of the above (D)</p> Signup and view all the answers

How does the concept of 'adaptation' contribute to the survival of a species?

<p>It ensures the species' ability to thrive in a changing environment (A)</p> Signup and view all the answers

What is the primary difference between the roles of natural selection and artificial selection?

<p>Natural selection favors survival and reproduction, while artificial selection favors specific traits for human benefit (D)</p> Signup and view all the answers

Which of these is NOT a characteristic of natural selection?

<p>Selective breeding by humans (D)</p> Signup and view all the answers

Flashcards

Mass Selection

Improving crop qualities by selecting offspring each generation for open pollination.

Clonal Selection

A process for good-quality hybrids that can't reproduce, using asexual reproduction methods.

Crossbreeding

Combining traits from two different breeds or species through mating or emasculation.

Somatic Hybridization

Fusing protoplasts from two different plants to express desirable traits.

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Genetic Engineering

A modern method that introduces genes from a different organism to improve traits.

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Protein Data Bank (PDB)

A large database containing the 3D structures of proteins, DNA, and RNA.

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Protein Resolution

The smallest distance between two distinguishable features in protein structure, measured in Angstroms.

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DNA Replication

The process of duplicating genetic material in cells for growth and reproduction.

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Meselson-Stahl Experiment

An experiment that demonstrated the semiconservative nature of DNA replication.

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Replication Bubble

The site where DNA replication occurs in both directions during synthesis.

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Priming in Replication

The process where RNA polymerase makes a primer for DNA polymerase to extend.

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Selective Breeding

A method of breeding where organisms with desirable traits are chosen to produce offspring.

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Abiotic Synthesis

The formation of small organic molecules from nonliving sources.

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Macromolecules

Large complex molecules, such as proteins and nucleic acids, formed from smaller organic units.

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Protocells

Simple vesicles with membranes that maintain a different internal environment.

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Self-Replicating Molecules

Molecules capable of making copies of themselves, enabling inheritance.

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Reducing Environment

An atmosphere with abundant electrons, helping organic compounds to form.

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Miller-Urey Experiment

An experiment demonstrating abiotic synthesis of organic compounds mimicking early Earth conditions.

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Vesicles

Fluid-filled compartments with a membrane that can exhibit life properties.

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RNA Monomers

The building blocks of RNA that can form spontaneously from simpler molecules.

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Heterochrony

Changes in the rate and timing of development affecting body part growth.

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Paedomorphosis

Retention of juvenile traits in sexually mature organisms due to accelerated reproductive organ development.

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Homeotic gene

Genes that control the positioning and spatial arrangement of body parts during development.

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Hox gene

A specific class of homeotic genes that determine the body plan of an embryo along the head-tail axis.

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Adaptive Radiation

A period of rapid evolution where organisms diversify to fill different ecological niches.

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Gene Duplication

A process where a segment of DNA is copied, potentially leading to new gene functions and traits.

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Developmental Genes

Genes that dictate the development and morphology of an organism.

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Evolutionary Change

Long-term changes in genetic makeup and structure of populations over time.

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Population

A group of individuals of the same species living in an area and interbreeding.

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Evolution

The process of transformation of species over time through genetic changes.

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Founder Species

The initial species that diverges into different lineages through evolution.

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Natural Selection

The process where traits that improve survival are favored in a species.

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Adaptation

The traits that enhance survival become more common in a population over time.

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Variation

The differences in traits among individuals of a population.

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Overproduction

Species tend to produce more offspring than can survive to maturity.

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Selection

Some individuals survive longer and reproduce more than others due to favorable traits.

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Artificial Selection

The human-controlled process of choosing specific plants or animals for breeding.

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Speciation

The process through which new distinct species arise from a common ancestor.

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Later Cynodont

Later cynodonts had teeth with complex cusp patterns and two jaw hinges: the original articular quadrate and a new dentary-squamosal hinge.

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Very Late Cynodont

Very late cynodonts lost the original articular-quadrate hinge, using only the dentary-squamosal hinge, similar to living mammals.

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Articular Bone

A bone that, in non-mammalian cynodonts, connected the jaw and later migrated to the ear region.

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Quadrate Bone

A bone in cynodonts that also shifted to the ear, contributing to hearing in mammals.

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Malleus Bone

The hammer-shaped bone in the ear of mammals, evolved from the articular bone of cynodonts.

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Incus Bone

The anvil-shaped bone in the ear evolved from the quadrate bone of cynodonts.

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Phanerozoic Eon

The eon representing visible life, characterized by abundant fossils and major changes in life forms.

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Cenozoic Era

Era known as the age of mammals, marking significant evolutionary developments in mammals.

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Quaternary Period

A geological period within the Cenozoic Era that includes the time of human evolution.

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Tertiary Period

The period that is part of the Cenozoic Era, marked by mammal diversity.

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Mesozoic Era

The era known as the age of reptiles, including the time of dinosaurs and first flowering plants.

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Cretaceous Period

The last period of the Mesozoic Era, known for the extinction of dinosaurs and the rise of flowering plants.

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Jurassic Period

A period in the Mesozoic Era where dinosaurs were diverse and the first birds appeared.

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Triassic Period

The period marking the first appearance of mammals and the earliest dinosaurs in the Mesozoic Era.

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Study Notes

DNA Structure

  • DNA is made of two polynucleotide chains held together by complementary base pairing.
  • The strands run antiparallel (one in 5'→3' direction, the other in 3'→5').
  • Rosalind Franklin and Maurice Wilkins used X-ray crystallography to analyze DNA structure.
  • Base stacking contributes to DNA's thermodynamic stability.
  • DNA is a right-handed double helix.
  • DNA has major and minor grooves.
  • DNA exists in three conformations (B, A, and Z DNA) differing in base pairs per turn and helix shape.

DNA Properties

  • B-DNA: 92% relative humidity, 10 base pairs per turn, right-handed.
  • A-DNA: 70% relative humidity, 11 base pairs per turn, right-handed.
  • Z-DNA: Low/high salt concentration, 12 base pairs per turn, left-handed.

Chargaff's Rules

  • Purine content = pyrimidine content.
  • Adenine = Thymine
  • Guanine = Cytosine

DNA Structure (Postulated by Watson and Crick)

  • Complementary base pairing maintains uniform DNA size.
  • Pairings involve specific hydrogen bonding.
  • DNA structure is helical (like a twisted ladder).

Eukaryotic DNA

  • Linear with telomeres (distinct ends).
  • Organized as chromatin (DNA + proteins).
  • Packed into nucleosomes, 30-nm fibers, and metaphase chromosomes via histones.

RNA Structure and Function

  • RNA is single-stranded.
  • Replaces thymine with uracil.
  • Utilizes ribose instead of deoxyribose.
  • Product of DNA transcription.
  • Some RNA forms have enzymatic functions (ribozymes).
  • Examples: RNase P (catalyzes tRNA synthesis), and ribozymes.
  • RNA acts as a translator between DNA and protein.

DNA Replication

  • DNA replication is semiconservative.
  • Each strand serves as a template during replication.
  • Replication is bidirectional and 5' to 3'.
  • Replication happens within replication bubbles.

Protein Structure

  • Amino acids are the building blocks of proteins.
  • Amino acids are linked by peptide bonds into polypeptides/proteins.
  • Proteins have primary, secondary, tertiary, and quaternary structures.

Protein Data Bank (PDB)

  • Database of 3D protein structures.
  • Allows viewing and analysis of proteins' 3D structures.

Fossils and Earth's Timeline

  • Fossils show macroevolutionary trends.
  • Four main stages to life's emergence: abiotic synthesis of organic molecules, molecule bonding, formation of protocells, and self-replicating molecules.
  • Earth's timeline is divided into Eons, Eras, Periods, and Epochs.
  • The earliest single-celled organisms emerged around 3.5 billion years ago.
  • Photosynthesis and the oxygen revolution are important milestones in life's history, first emerging around 2.7 billion years ago.

Multicellularity

  • Complex eukaryotic cells sparked multicellularity evolution.
  • Ediacaran biota were early multicellular eukaryotes.

The Cambrian Explosion

  • Cambrian Explosion marks the rapid appearance of many animal phyla.
  • Severe ice ages may have limited multicellular diversity.

Adaptive Radiations

  • Adaptive radiation is a rapid diversification of species.
  • This happens when organisms form new species and fill diverse niches.

Natural Selection and Artificial Selection

  • Natural Selection: Heritable traits increase survival and reproduction in a specific environment.
  • Artificial Selection: Humans select traits in plants and animals for desired characteristics.
  • Natural selection results in changes in populations over time.

Evolutionary Biology

  • Evolutionary biology studies the origin and history of life.
  • The pattern of evolutionary change is revealed through data from various scientific disciplines.
  • Evolutionary mechanisms produce observable evolutionary changes.
  • Some key concepts like homology and fossils show evidence of evolution.
  • Biogeography (the geographical distribution of species) also supports the theory of evolution.

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