COPY: DNA Replication mechanisms
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Questions and Answers

During DNA replication, which enzyme is responsible for relieving the torsional stress ahead of the replication fork by undoing supercoils?

  • DNA Gyrase (correct)
  • DNA Helicase
  • DNA Ligase
  • DNA Polymerase III

If a mutation were to prevent the function of single-stranded binding proteins during DNA replication, what would be the most likely direct consequence?

  • Okazaki fragments would not be joined together.
  • The DNA double helix would not be unwound.
  • RNA primers would not be synthesized.
  • The separated DNA strands would re-anneal. (correct)

Which of the following best describes the role of DNA ligase in DNA replication?

  • Synthesizing RNA primers to initiate DNA synthesis.
  • Proofreading and correcting errors in the newly synthesized DNA strand.
  • Unwinding the DNA double helix at the replication fork.
  • Joining Okazaki fragments on the lagging strand. (correct)

A point mutation occurs where a single nucleotide base is changed. If adenine (A) is replaced with guanine (G), what specific type of point mutation is this?

<p>Transition (A)</p> Signup and view all the answers

Which enzyme is primarily responsible for proofreading during DNA replication to ensure high fidelity in the newly synthesized strand?

<p>DNA Polymerase III (A)</p> Signup and view all the answers

In a population in Hardy-Weinberg equilibrium for a locus with two alleles, where the frequency of one allele is 0.7, what is the expected frequency of heterozygotes?

<p>0.42 (B)</p> Signup and view all the answers

A couple, both heterozygous for an autosomal recessive trait, are planning to have children. What is the probability that their first child will express the recessive trait?

<p>25% (C)</p> Signup and view all the answers

During which phase of the cell cycle does DNA replication occur?

<p>S phase (D)</p> Signup and view all the answers

If a coding sequence in DNA is 5'-ACG-3', what is the corresponding codon sequence in mRNA after transcription?

<p>5'-UGC-3' (A)</p> Signup and view all the answers

A scientist is studying a family pedigree and observes that a certain disease appears in every generation, and that affected fathers always pass the trait to their daughters but not to their sons. What is the most likely mode of inheritance for this disease?

<p>X-linked dominant (D)</p> Signup and view all the answers

Which of the following statements best describes mitosis?

<p>Genetic material is duplicated, equally divided between two daughter cells (B)</p> Signup and view all the answers

When a recessive trait is expressed, it means that:

<p>Two genes carrying the trait were present. (B)</p> Signup and view all the answers

In a pedigree, the “index case” is another name for:

<p>Propositus. (C)</p> Signup and view all the answers

Which of the following nitrogenous bases make up DNA?

<p>Adenine, cytosine, guanine, thymine (B)</p> Signup and view all the answers

Proteins and peptides are composed of:

<p>Linear arrangements of amino acids. (D)</p> Signup and view all the answers

Which phenotype(s) could not result from the mating of a Jk(a+b+) female and a Jk(a-b+) male?

<p>Jk(a–b–) (D)</p> Signup and view all the answers

Exon refers to:

<p>The coding region of a gene. (B)</p> Signup and view all the answers

PCR technology can be used to:

<p>Amplify small amounts of DNA. (A)</p> Signup and view all the answers

Transcription can be defined as:

<p>Synthesis of RNA using DNA as a template. (C)</p> Signup and view all the answers

When a male possesses a phenotypic trait that he passes to all his daughters and none of his sons, the trait is said to be:

<p>X-linked dominant. (A)</p> Signup and view all the answers

When a female possesses a phenotypic trait that she passes to all of her sons and none of her daughters, the trait is said to be:

<p>X-linked recessive. (B)</p> Signup and view all the answers

DNA is replicated:

<p>Semiconservatively from DNA. (A)</p> Signup and view all the answers

RNA is processed:

<p>After RNA is copied from DNA template. (A)</p> Signup and view all the answers

Translation of proteins from RNA takes place:

<p>On the ribosomes in the cytoplasm of the cell. (A)</p> Signup and view all the answers

Meiosis is necessary to:

<p>Generate new DNA sequences in daughter cells. (C)</p> Signup and view all the answers

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