Podcast
Questions and Answers
What direction is the leading strand synthesized during DNA replication?
What direction is the leading strand synthesized during DNA replication?
Which enzyme is responsible for initiating the Okazaki fragments on the lagging strand?
Which enzyme is responsible for initiating the Okazaki fragments on the lagging strand?
What is the function of DNA ligase in the synthesis of the lagging strand?
What is the function of DNA ligase in the synthesis of the lagging strand?
Which of the following statements about the lagging strand is correct?
Which of the following statements about the lagging strand is correct?
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During DNA replication, which enzyme is responsible for replacing RNA primers with DNA nucleotides?
During DNA replication, which enzyme is responsible for replacing RNA primers with DNA nucleotides?
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Study Notes
DNA Replication - Lagging Strand
- Lagging strand synthesis involves an alternating mix of RNA primers and new daughter DNA.
- Fragments of daughter DNA are called Okazaki fragments.
- Okazaki fragments are shown in the image as green boxes.
- All RNA primers must be replaced with DNA.
- DNA polymerase I removes RNA primers and replaces them with DNA (shown in pink box).
- DNA polymerase I cannot complete the final covalent bond in the sugar-phosphate backbone.
- DNA ligase completes the final bond between Okazaki fragments. DNA ligase is shown in the orange box.
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Description
Test your knowledge on the processes involved in lagging strand synthesis during DNA replication. Understand the role of RNA primers, Okazaki fragments, and the enzymes involved such as DNA polymerase I and DNA ligase. This quiz will help solidify your understanding of these critical concepts in molecular biology.
