DNA Replication Enzymes in Prokaryotes and Eukaryotes Part 1 Quiz

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What is the primary function of DNA polymerase I in E. coli?

To proofread and correct errors during DNA synthesis

To synthesize new DNA strands in the 3'->5' direction

To remove RNA primers during DNA replication (correct)

To repair damaged DNA

Which DNA polymerase in E. coli is responsible for the bulk of DNA replication?

DNA polymerase II

DNA polymerase III (correct)

DNA polymerase I

DNA polymerase IV

What is the primary function of DNA polymerase IV in E. coli?

To remove RNA primers during DNA replication

To participate in DNA repair processes (correct)

To replicate DNA during normal cell division

To proofread and correct errors during DNA synthesis

Which DNA polymerase in E. coli has 3'->5' exonuclease (proofreading) activity?

Both DNA polymerase I and DNA polymerase III Signup and view all the answers

What is the role of the $\epsilon$ (dnaQ) subunit in the E. coli DNA polymerase III holoenzyme?

It provides the 3'->5' exonuclease (proofreading) activity Signup and view all the answers

Which DNA polymerase in E. coli is primarily responsible for DNA repair processes?

DNA polymerase IV and DNA polymerase V Signup and view all the answers

Which pathway enables most organisms to synthesize nucleotides from nucleosides or bases available through diet or degradation of nucleic acids?

Salvage pathway Signup and view all the answers

In animals, which route provides the major source of bases for nucleotide synthesis?

Extracellular hydrolysis of ingested nucleic acids Signup and view all the answers

Which enzyme is involved in the de novo pathway of Pyrimidine Biosynthesis?

Orotate phosphoriboxyltransferase Signup and view all the answers

What is the key function of DHO dehydrogenase in nucleotide biosynthesis?

Oxidation of DHO to form orotate Signup and view all the answers

Which enzyme catalyzes the formation of Carbamoyl phosphate in the de novo pathway of Pyrimidine Biosynthesis?

Carbamoyl phosphate synthase II Signup and view all the answers

What is the primary difference between de novo and salvage pathways in nucleotide biosynthesis?

De novo pathways use precursors directly, while salvage pathways recycle nucleotide breakdown products. Signup and view all the answers

DNA Replication Enzymes in Prokaryotes and Eukaryotes Part 1 Quiz

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Questions and Answers

What is the primary function of DNA polymerase I in E. coli?

Which DNA polymerase in E. coli is responsible for the bulk of DNA replication?

What is the primary function of DNA polymerase IV in E. coli?

Which DNA polymerase in E. coli has 3'->5' exonuclease (proofreading) activity?

What is the role of the $\epsilon$ (dnaQ) subunit in the E. coli DNA polymerase III holoenzyme?

Which DNA polymerase in E. coli is primarily responsible for DNA repair processes?

Which pathway enables most organisms to synthesize nucleotides from nucleosides or bases available through diet or degradation of nucleic acids?

In animals, which route provides the major source of bases for nucleotide synthesis?

Which enzyme is involved in the de novo pathway of Pyrimidine Biosynthesis?

What is the key function of DHO dehydrogenase in nucleotide biosynthesis?

Which enzyme catalyzes the formation of Carbamoyl phosphate in the de novo pathway of Pyrimidine Biosynthesis?

What is the primary difference between de novo and salvage pathways in nucleotide biosynthesis?

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