DNA Replication Enzymes in Prokaryotes and Eukaryotes Part 1 Quiz
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DNA Replication Enzymes in Prokaryotes and Eukaryotes Part 1 Quiz

Test your knowledge on the enzymes involved in DNA replication in both prokaryotes and eukaryotes. Learn about the functions of DNA polymerases, including DNA polymerase I which plays a crucial role in DNA replication.

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Questions and Answers

What is the primary function of DNA polymerase I in E. coli?

To remove RNA primers during DNA replication

Which DNA polymerase in E. coli is responsible for the bulk of DNA replication?

DNA polymerase III

What is the primary function of DNA polymerase IV in E. coli?

To participate in DNA repair processes

Which DNA polymerase in E. coli has 3'->5' exonuclease (proofreading) activity?

<p>Both DNA polymerase I and DNA polymerase III</p> Signup and view all the answers

What is the role of the $\epsilon$ (dnaQ) subunit in the E. coli DNA polymerase III holoenzyme?

<p>It provides the 3'-&gt;5' exonuclease (proofreading) activity</p> Signup and view all the answers

Which DNA polymerase in E. coli is primarily responsible for DNA repair processes?

<p>DNA polymerase IV and DNA polymerase V</p> Signup and view all the answers

Which pathway enables most organisms to synthesize nucleotides from nucleosides or bases available through diet or degradation of nucleic acids?

<p>Salvage pathway</p> Signup and view all the answers

In animals, which route provides the major source of bases for nucleotide synthesis?

<p>Extracellular hydrolysis of ingested nucleic acids</p> Signup and view all the answers

Which enzyme is involved in the de novo pathway of Pyrimidine Biosynthesis?

<p>Orotate phosphoriboxyltransferase</p> Signup and view all the answers

What is the key function of DHO dehydrogenase in nucleotide biosynthesis?

<p>Oxidation of DHO to form orotate</p> Signup and view all the answers

Which enzyme catalyzes the formation of Carbamoyl phosphate in the de novo pathway of Pyrimidine Biosynthesis?

<p>Carbamoyl phosphate synthase II</p> Signup and view all the answers

What is the primary difference between de novo and salvage pathways in nucleotide biosynthesis?

<p>De novo pathways use precursors directly, while salvage pathways recycle nucleotide breakdown products.</p> Signup and view all the answers

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