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Questions and Answers
What is the primary function of the Origin Recognition Complex (ORC) in DNA replication?
What is the primary function of the Origin Recognition Complex (ORC) in DNA replication?
- To provide the template for the new telomere
- To ensure that each region of the DNA is replicated once and only once in each S phase (correct)
- To synthesize new RNA primers
- To facilitate the disassembly of histones in front of the replication fork
What is the role of histone chaperones in DNA replication?
What is the role of histone chaperones in DNA replication?
- To restore the full complement of histones (correct)
- To synthesize new RNA primers
- To facilitate the assembly of new nucleosomes behind the replication fork
- To disassemble histones in front of the replication fork
What is the consequence of the lagging-strand replication machinery reaching the end of the chromosome?
What is the consequence of the lagging-strand replication machinery reaching the end of the chromosome?
- A reversal of the replication direction
- An incomplete replication resulting in a short ssDNA region at the 3’ end of the lagging-strand DNA product (correct)
- A pause in the replication process
- A complete replication of the chromosome
What is the function of telomerase in DNA replication?
What is the function of telomerase in DNA replication?
What is the composition of telomerase?
What is the composition of telomerase?
What is the outcome of the shortening of one of the two products in the next round of replication?
What is the outcome of the shortening of one of the two products in the next round of replication?
What is the purpose of telomere packaging into specialized structures?
What is the purpose of telomere packaging into specialized structures?
What is the process by which DNA replication is terminated?
What is the process by which DNA replication is terminated?
What is the role of chaperone FACT in DNA replication?
What is the role of chaperone FACT in DNA replication?
What is the consequence of the incomplete replication of the lagging-strand DNA product?
What is the consequence of the incomplete replication of the lagging-strand DNA product?
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