Podcast
Questions and Answers
What can lead to the formation of loops in the template strand during DNA replication?
What can lead to the formation of loops in the template strand during DNA replication?
- Deamination
- Replication slippage (correct)
- Tautomeric shifts
- Depurination
Which genetic disorder can result from the skipping over of loops by DNA polymerase during replication?
Which genetic disorder can result from the skipping over of loops by DNA polymerase during replication?
- Fragile-X syndrome (correct)
- Huntington’s disease
- Alkaptonuria
- Sickle cell anemia
What process involves the spontaneous change from one tautomer to another, leading to non-complementary base-pairing?
What process involves the spontaneous change from one tautomer to another, leading to non-complementary base-pairing?
- Deamination
- Depurination
- Induced replication
- Tautomeric shifts (correct)
What is the term for the random loss of a nucleotide's purine base?
What is the term for the random loss of a nucleotide's purine base?
Which mutagen can add bulky carbon chains like methyls or ethyls to DNA bases?
Which mutagen can add bulky carbon chains like methyls or ethyls to DNA bases?
What type of radiation sensitivity can base analogs contribute to?
What type of radiation sensitivity can base analogs contribute to?
If cytosine loses an amino group and an oxygen is added in its place, what base does it change to?
If cytosine loses an amino group and an oxygen is added in its place, what base does it change to?
Which process involves the filling of an apurinic site with an adenine nucleotide?
Which process involves the filling of an apurinic site with an adenine nucleotide?
What is the function of enhancers in gene regulation?
What is the function of enhancers in gene regulation?
Which of the following actions do silencers perform in gene regulation?
Which of the following actions do silencers perform in gene regulation?
What effect does methylation of DNA have on transcription?
What effect does methylation of DNA have on transcription?
What is RNA-induced gene silencing?
What is RNA-induced gene silencing?
Which enzyme is responsible for cleaving double-stranded RNA during a viral infection to produce siRNA?
Which enzyme is responsible for cleaving double-stranded RNA during a viral infection to produce siRNA?
What is the function of microRNA in gene expression regulation?
What is the function of microRNA in gene expression regulation?
Which complex is responsible for RNA-induced silencing in gene regulation?
Which complex is responsible for RNA-induced silencing in gene regulation?
What is the role of a repressor protein in negative control?
What is the role of a repressor protein in negative control?
Which of the following describes the function of the allosteric domain of a repressor protein?
Which of the following describes the function of the allosteric domain of a repressor protein?
What is the main function of an activator protein in positive control?
What is the main function of an activator protein in positive control?
How do most activator proteins become active for transcription initiation?
How do most activator proteins become active for transcription initiation?
What factor is expressed during the heat shock response due to unstable conditions?
What factor is expressed during the heat shock response due to unstable conditions?
What role do chaperone proteins play in the heat shock response?
What role do chaperone proteins play in the heat shock response?
What are riboswitches and how do they control gene expression?
What are riboswitches and how do they control gene expression?
Which DNA repair mechanism involves the swapping of genetic material between homologous DNA molecules?
Which DNA repair mechanism involves the swapping of genetic material between homologous DNA molecules?
Which stage of meiosis does homologous recombination occur in eukaryotes?
Which stage of meiosis does homologous recombination occur in eukaryotes?
Which type of mutation results in the translation being stopped early due to a stop codon?
Which type of mutation results in the translation being stopped early due to a stop codon?
Which type of mutation results in a triplet code that still codes for the same amino acid?
Which type of mutation results in a triplet code that still codes for the same amino acid?
Which mechanism of DNA repair is likely to involve kinase and BRCA1?
Which mechanism of DNA repair is likely to involve kinase and BRCA1?
Which hypothesis suggests that mutations arise from adaptations to the environment?
Which hypothesis suggests that mutations arise from adaptations to the environment?
Which type of mutation involves the replacement of one pyrimidine by another?
Which type of mutation involves the replacement of one pyrimidine by another?
Which type of mutation involves the replacement of a pyrimidine by a purine or vice versa?
Which type of mutation involves the replacement of a pyrimidine by a purine or vice versa?
What type of mutation can be caused by the addition of bulky adducts?
What type of mutation can be caused by the addition of bulky adducts?
How do hydroxylating agents cause mutations?
How do hydroxylating agents cause mutations?
What type of damage can be caused by transposable DNA elements?
What type of damage can be caused by transposable DNA elements?
What type of radiation can produce reactive oxygen molecules that damage DNA?
What type of radiation can produce reactive oxygen molecules that damage DNA?
What is the role of activator proteins in transcriptional regulation?
What is the role of activator proteins in transcriptional regulation?
What is the role of repressor proteins in transcriptional regulation?
What is the role of repressor proteins in transcriptional regulation?
What is a characteristic of enhancers and silencers in eukaryotes?
What is a characteristic of enhancers and silencers in eukaryotes?
What is the purpose of the Ames test?
What is the purpose of the Ames test?
