DNA Repair: Fixing Mismatched Nucleotides

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What is the consequence of mutations in repair genes?

Greater susceptibility to certain types of cancer

What is the primary role of repair enzymes in DNA repair?

To remove mismatched nucleotides from the DNA strand

What is the purpose of DNA polymerase in the DNA repair process?

To fill in the gap left by the repair enzymes

What is the result of a failure in DNA repair?

Mutations and chromosome breaks persist

What triggers the action of repair enzymes?

The presence of a mismatched nucleotide

What is a primary source of genetic variation in organisms?

Mutations

What type of mutations can cause uncontrolled cell division and lead to cancer?

Mutations in somatic cells

What is a common cause of spontaneous mutations during DNA replication?

Mistakes during DNA copying

What type of mutation occurs when a base pair is substituted, but the resulting amino acid sequence remains the same?

Silent mutation

Which of the following is an example of an environmental factor that can cause mutations?

UV light exposure

How do mutations in germ cells affect organisms?

They can be passed to future generations

What is the result of an undetected error during DNA replication?

A mutation in the DNA

What is the term for agents that increase the rate of mutations?

Mutagens

What type of mutation is caused by the insertion or deletion of base pairs, resulting in a changed reading frame?

Frameshift mutation

What is a key factor that determines the effects of a mutation on an organism?

All of the above

What is the result of a nonsense mutation?

A shortened protein is produced

What is the role of DNA polymerase during DNA replication?

To detect and repair errors

Test your knowledge on the process of DNA repair, where enzymes identify and correct mismatched nucleotides in the DNA double helix. Learn how repair enzymes scan for distortions, break the new strand, remove mismatched bases, and fill in the gap with the correct nucleotides.

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