DNA Discovery & Structure Overview
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Questions and Answers

What was the primary research focus of Sydney Brenner after completing his doctoral studies?

  • Viral genetics and X-ray crystallography
  • Building 3D models of DNA
  • The structure and function of proteins
  • Developmental genetics and molecular biology (correct)
  • Which component of DNA forms part of its backbone structure?

  • Guanine and Cytosine
  • Phosphoric Acid and Sugar (correct)
  • Protein Amino Acids
  • Adenine and Thymine
  • Whose prior research data played a critical role in Watson and Crick's development of the DNA model?

  • Gregory Mendel
  • Rosalind Franklin (correct)
  • Sydney Brenner
  • Linus Pauling
  • Who shared the discovery of the protein amino acid encoding process with Sydney Brenner?

    <p>Francis Crick (D)</p> Signup and view all the answers

    Which key player in the DNA structure discovery was recognized for their work on programmed cell death?

    <p>Sydney Brenner (C)</p> Signup and view all the answers

    What structural feature did Watson and Crick propose as the fundamental arrangement of DNA?

    <p>Double helix (A)</p> Signup and view all the answers

    Which element was NOT a key piece of evidence for Watson and Crick's DNA model development?

    <p>Pure mathematics (B)</p> Signup and view all the answers

    Which of the following does NOT make up the DNA molecule?

    <p>Protein Amino Acids (C)</p> Signup and view all the answers

    Who are credited with meticulously compiling evidence to develop the model of DNA?

    <p>James Watson and Francis Crick (D)</p> Signup and view all the answers

    Why was the publication of the DNA model considered ground breaking despite its brevity?

    <p>It revolutionized understanding of heredity. (A)</p> Signup and view all the answers

    What aspect of DNA did Watson and Crick successfully determine through model building?

    <p>The three-dimensional structure as a double helix (B)</p> Signup and view all the answers

    Flashcards

    DNA discovery timeframe

    The collaborative effort took only 18 months.

    Sydney Brenner

    South African biologist known for contributions to molecular biology.

    Crick and Watson

    Scientists who developed the DNA model; compiled evidence from various fields.

    Rosalind Franklin's role

    Provided crucial data for determining DNA's structure.

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    DNA structure components

    DNA consists of a backbone (phosphoric acid and sugar) and four bases: A, T, G, C.

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    Double helix

    The shape formed by the two strands of DNA.

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    Significance of DNA structure

    Revolutionized the understanding of heredity and genetic information.

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    Research fields influenced by DNA

    Opened up avenues in genetics, medicine, and biotechnology.

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    Publication of discovery

    Published in a groundbreaking one-page paper.

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    Protein encoding process

    Discovered by Brenner and Crick, how genetic code translates to proteins.

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    Study Notes

    DNA Discovery

    • DNA's structure was discovered in just 18 months of research
    • A model of DNA was built in 3 days.
    • A scientific paper describing the discovery was published in just one page.

    Key Players in DNA Research

    • Sydney Brenner: South African biologist who contributed to understanding DNA and cell development
    • Francis Crick: contributed to the discovery of the DNA molecule
    • James Watson: contributed to the discovery of the DNA molecule

    DNA Structure

    • DNA is a molecule composed of a sugar-phosphate backbone
    • Four nitrogenous bases are present in the DNA structure
      • adenine (A),
      • thymine (T),
      • guanine (G),
      • cytosine (C)
    • The sequence of these bases is the genetic code.
    • The key challenge before the discovery was figuring out how these components fit together to form a DNA molecule
    • X-ray crystallography, viral genetics, and physics played a major role in the initial model building and understanding the structure.

    Dynamic Duo

    • Crick and Watson used existing knowledge in multiple scientific disciplines, combining this expertise and building 3D models, to piece together the DNA structure
    • They started with existing data and previous experimental failures and built on this to create their final model.

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    Description

    Explore the groundbreaking discovery of DNA and its structure. Learn about key figures like Watson and Crick, the composition of DNA, and the techniques used in its discovery. This quiz delves into the history and science behind one of life's fundamental molecules.

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