DNA Damage Quiz

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What are the two ways in which DNA damage (lesion) can occur?

Inherited and acquired mutations

Environmental and accidental factors

Single-strand damage and double-strand damage (correct)

Direct repair and Excision repair

Which factor is not listed as a cause of DNA damage (lesion)?

Radon gas

Aflatoxin

UV light

Inherited mutations (correct)

What are the two ways in which DNA can become mutated?

Direct repair and Excision repair

Point mutation and frame shift mutation

Transversion mutation and transition mutation

Inherited parent to child and acquired environmental damage (correct)

What is a point mutation?

A localised mutation resulting in the substitution of one base pair for a different base pair Signup and view all the answers

Which type of mutation is generated at a higher frequency than the other?

Transition mutation Signup and view all the answers

What are the two ways of repairing damaged DNA (lesion)?

Direct repair and Excision repair Signup and view all the answers

What are the two types of DNA damage (lesion)?

Single-strand damage and double-strand damage Signup and view all the answers

What are mutagens?

Chemicals or physical agents that cause damage/lesion to the genetic material Signup and view all the answers

What is a frame shift mutation?

A type of mutation that alters the reading frame of the genetic material Signup and view all the answers

Which factor is not listed as a cause of DNA damage (lesion)?

Inherited mutations Signup and view all the answers

What type of mutation substitutes a purine for a purine, and a pyrimidine for a pyrimidine?

Transition mutation Signup and view all the answers

Which type of mutation substitutes a purine for a pyrimidine, and a pyrimidine for a purine?

Transversion mutation Signup and view all the answers

What is the outcome of a point mutation in the β-globin chain of normal hemoglobin?

Sickle-cell anemia Signup and view all the answers

What is the mutation type in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene?

Deletion of a codon (3 nucleotides) Signup and view all the answers

Which mutation type results in the deletion or insertion of a nucleotide?

Frame shift mutation Signup and view all the answers

What can help in choosing the best biotech approach in treating a disease?

Understanding gene mutation and its types Signup and view all the answers

What are the most common types of mutation?

Point mutation and frame shift Signup and view all the answers

What can prevent the development of a disorder by fixing lesions in the DNA?

Cell's instant repair of DNA Signup and view all the answers

What amino acid is replaced with valine in sickle-cell anemia?

Glutamic acid Signup and view all the answers

What type of mutation can be caused by oxidative deamination and tautomerization?

Transition mutation Signup and view all the answers

DNA Damage Quiz

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Questions and Answers

What are the two ways in which DNA damage (lesion) can occur?

Which factor is not listed as a cause of DNA damage (lesion)?

What are the two ways in which DNA can become mutated?

What is a point mutation?

Which type of mutation is generated at a higher frequency than the other?

What are the two ways of repairing damaged DNA (lesion)?

What are the two types of DNA damage (lesion)?

What are mutagens?

What is a frame shift mutation?

Which factor is not listed as a cause of DNA damage (lesion)?

What type of mutation substitutes a purine for a purine, and a pyrimidine for a pyrimidine?

Which type of mutation substitutes a purine for a pyrimidine, and a pyrimidine for a purine?

What is the outcome of a point mutation in the β-globin chain of normal hemoglobin?

What is the mutation type in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene?

Which mutation type results in the deletion or insertion of a nucleotide?

What can help in choosing the best biotech approach in treating a disease?

What are the most common types of mutation?

What can prevent the development of a disorder by fixing lesions in the DNA?

What amino acid is replaced with valine in sickle-cell anemia?

What type of mutation can be caused by oxidative deamination and tautomerization?

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