DNA Damage Quiz

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Questions and Answers

What are the two ways in which DNA damage (lesion) can occur?

  • Inherited and acquired mutations
  • Environmental and accidental factors
  • Single-strand damage and double-strand damage (correct)
  • Direct repair and Excision repair

Which factor is not listed as a cause of DNA damage (lesion)?

  • Radon gas
  • Aflatoxin
  • UV light
  • Inherited mutations (correct)

What are the two ways in which DNA can become mutated?

  • Direct repair and Excision repair
  • Point mutation and frame shift mutation
  • Transversion mutation and transition mutation
  • Inherited parent to child and acquired environmental damage (correct)

What is a point mutation?

<p>A localised mutation resulting in the substitution of one base pair for a different base pair (C)</p> Signup and view all the answers

Which type of mutation is generated at a higher frequency than the other?

<p>Transition mutation (B)</p> Signup and view all the answers

What are the two ways of repairing damaged DNA (lesion)?

<p>Direct repair and Excision repair (B)</p> Signup and view all the answers

What are the two types of DNA damage (lesion)?

<p>Single-strand damage and double-strand damage (B)</p> Signup and view all the answers

What are mutagens?

<p>Chemicals or physical agents that cause damage/lesion to the genetic material (A)</p> Signup and view all the answers

What is a frame shift mutation?

<p>A type of mutation that alters the reading frame of the genetic material (B)</p> Signup and view all the answers

Which factor is not listed as a cause of DNA damage (lesion)?

<p>Inherited mutations (D)</p> Signup and view all the answers

What type of mutation substitutes a purine for a purine, and a pyrimidine for a pyrimidine?

<p>Transition mutation (D)</p> Signup and view all the answers

Which type of mutation substitutes a purine for a pyrimidine, and a pyrimidine for a purine?

<p>Transversion mutation (B)</p> Signup and view all the answers

What is the outcome of a point mutation in the β-globin chain of normal hemoglobin?

<p>Sickle-cell anemia (A)</p> Signup and view all the answers

What is the mutation type in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene?

<p>Deletion of a codon (3 nucleotides) (D)</p> Signup and view all the answers

Which mutation type results in the deletion or insertion of a nucleotide?

<p>Frame shift mutation (A)</p> Signup and view all the answers

What can help in choosing the best biotech approach in treating a disease?

<p>Understanding gene mutation and its types (C)</p> Signup and view all the answers

What are the most common types of mutation?

<p>Point mutation and frame shift (D)</p> Signup and view all the answers

What can prevent the development of a disorder by fixing lesions in the DNA?

<p>Cell's instant repair of DNA (A)</p> Signup and view all the answers

What amino acid is replaced with valine in sickle-cell anemia?

<p>Glutamic acid (C)</p> Signup and view all the answers

What type of mutation can be caused by oxidative deamination and tautomerization?

<p>Transition mutation (B)</p> Signup and view all the answers

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9-mutation.ppt

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