20 Questions
What are the two ways in which DNA damage (lesion) can occur?
Single-strand damage and double-strand damage
Which factor is not listed as a cause of DNA damage (lesion)?
Inherited mutations
What are the two ways in which DNA can become mutated?
Inherited parent to child and acquired environmental damage
What is a point mutation?
A localised mutation resulting in the substitution of one base pair for a different base pair
Which type of mutation is generated at a higher frequency than the other?
Transition mutation
What are the two ways of repairing damaged DNA (lesion)?
Direct repair and Excision repair
What are the two types of DNA damage (lesion)?
Single-strand damage and double-strand damage
What are mutagens?
Chemicals or physical agents that cause damage/lesion to the genetic material
What is a frame shift mutation?
A type of mutation that alters the reading frame of the genetic material
Which factor is not listed as a cause of DNA damage (lesion)?
Inherited mutations
What type of mutation substitutes a purine for a purine, and a pyrimidine for a pyrimidine?
Transition mutation
Which type of mutation substitutes a purine for a pyrimidine, and a pyrimidine for a purine?
Transversion mutation
What is the outcome of a point mutation in the β-globin chain of normal hemoglobin?
Sickle-cell anemia
What is the mutation type in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene?
Deletion of a codon (3 nucleotides)
Which mutation type results in the deletion or insertion of a nucleotide?
Frame shift mutation
What can help in choosing the best biotech approach in treating a disease?
Understanding gene mutation and its types
What are the most common types of mutation?
Point mutation and frame shift
What can prevent the development of a disorder by fixing lesions in the DNA?
Cell's instant repair of DNA
What amino acid is replaced with valine in sickle-cell anemia?
Glutamic acid
What type of mutation can be caused by oxidative deamination and tautomerization?
Transition mutation
Test your knowledge of DNA damage with this quiz. Learn about the types of DNA damage, including point mutations and frame shift mutations, and explore the factors that can cause DNA damage, such as UV light and radon gas.
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