13 Questions
What is DNA damage also known as?
Lesion
Which of the following is a factor causing DNA damage?
Cancer chemotherapy drugs
How is damaged DNA repaired?
Direct repair and Excision repair
What is a mutation?
An alteration to the genetic material that produces heritable change
What type of mutation results in the substitution of one base pair for a different base pair?
Point mutation
What type of point mutation substitutes a purine for a purine, and a pyrimidine for a pyrimidine?
Transition
Which type of mutation can be caused by oxidative deamination and tautomerization?
Transition
What type of point mutation substitutes a purine for a pyrimidine, and a pyrimidine for a purine?
Transversion
Which mutation type results in the deletion or insertion of a nucleotide?
Deletion
Sickle-cell anaemia is caused by a point mutation in the β-globin chain of normal hemoglobin, resulting in the substitution of which amino acid?
Valine (V)
Which mutation type is most common?
Point mutation
What outcome results from a point mutation in the CFTR gene associated with Cystic Fibrosis?
Deletion of a codon (3 nucleotides)
What can help in better utilizing biotechnology techniques to solve disorders associated with mutation?
Understanding mutation mechanisms
Test your knowledge on types of DNA damage, point mutations, and frame shift mutations. Learn about the factors causing DNA damage, including environmental, contamination, accidental, and extreme causes.
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