DNA Damage and Mutation Quiz

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Questions and Answers

What is the result of ROS species binding with guanine?

  • Cytosine
  • Thymine
  • 8-hydroxyl guanosine (correct)
  • Adenine

What happens during replication if DNA damage repair system fails to correct the error caused by 8-OHdG?

  • It creates transition mutation
  • It creates transversion mutation (correct)
  • It creates deletion mutation
  • It creates inversion mutation

What is the result of UV light attacking thymine bases?

  • Cytosine dimers
  • Adenine dimers
  • Thymine dimers (correct)
  • Guanine dimers

What is the effect of thymine dimers on DNA?

<p>It causes bending of DNA (C)</p> Signup and view all the answers

What is the function of DNA damage repair enzymes?

<p>To recognize and correct DNA damage (A)</p> Signup and view all the answers

What type of mutation is created by thymine dimers if DNA repair enzymes fail to correct the damage?

<p>Transversion mutation (C)</p> Signup and view all the answers

What is the result of ROS species binding with cytosine?

<p>8-hydroxyl cytosine (D)</p> Signup and view all the answers

What is the effect of 8-OHdG during replication?

<p>It creates transversion mutation (C)</p> Signup and view all the answers

What is the result of UV light attacking guanine bases?

<p>Guanine dimers (B)</p> Signup and view all the answers

What is the result of ROS species binding with adenine?

<p>8-hydroxyl adenine (D)</p> Signup and view all the answers

What is the effect of guanine dimers on DNA?

<p>It causes twisting of DNA (B)</p> Signup and view all the answers

What is the function of DNA damage repair system?

<p>To recognize and correct DNA damage (A)</p> Signup and view all the answers

What is the result of ROS species binding with guanine?

<p>8-hydroxyl guanosine (D)</p> Signup and view all the answers

What happens during replication if DNA damage repair system fails to correct the error caused by 8-OHdG?

<p>It creates transversion mutation (A)</p> Signup and view all the answers

What is the result of UV light attacking thymine bases?

<p>Thymine dimers (A)</p> Signup and view all the answers

What is the effect of thymine dimers on DNA?

<p>It causes bending of DNA (C)</p> Signup and view all the answers

What is the function of DNA damage repair enzymes?

<p>To recognize and correct DNA damage (A)</p> Signup and view all the answers

What type of mutation is created by thymine dimers if DNA repair enzymes fail to correct the damage?

<p>Transversion mutation (D)</p> Signup and view all the answers

What is the result of ROS species binding with cytosine?

<p>8-hydroxyl cytosine (D)</p> Signup and view all the answers

What is the effect of 8-OHdG during replication?

<p>It creates transversion mutation (D)</p> Signup and view all the answers

What is the result of UV light attacking guanine bases?

<p>Guanine dimers (A)</p> Signup and view all the answers

What is the result of ROS species binding with adenine?

<p>8-hydroxyl adenine (B)</p> Signup and view all the answers

What is the effect of guanine dimers on DNA?

<p>It causes twisting of DNA (A)</p> Signup and view all the answers

What is the function of DNA damage repair system?

<p>To recognize and correct DNA damage (D)</p> Signup and view all the answers

What is the result of ROS species binding with guanine?

<p>8-hydroxyl guanosine (C)</p> Signup and view all the answers

What happens during replication if DNA damage repair system fails to correct the error caused by 8-OHdG?

<p>8-OHdG can create transversion mutation (A)</p> Signup and view all the answers

What is the name of the mutation caused by purine to pyrimidine change?

<p>Transversion mutation (C)</p> Signup and view all the answers

What type of damage does UV light cause to thymine bases?

<p>Cross-linking of adjacent thymine bases (D)</p> Signup and view all the answers

What is the result of thymine dimers formation?

<p>Bending of DNA (D)</p> Signup and view all the answers

What is the name of the DNA damage repair system that recognizes and corrects errors?

<p>Excision repair system (B)</p> Signup and view all the answers

What is the result of failure of DNA damage repair enzymes to correct thymine dimer damage?

<p>Mutation during replication (D)</p> Signup and view all the answers

What is the name of the mutation caused by purine to pyrimidine change?

<p>Transversion mutation (B)</p> Signup and view all the answers

What is the name of the structural damage caused by thymine dimers?

<p>Structural damage (B)</p> Signup and view all the answers

What is the name of the enzyme that recognizes and corrects thymine dimer damage?

<p>Photolyase (A)</p> Signup and view all the answers

What is the name of the mutation caused by pyrimidine to pyrimidine change?

<p>Transition mutation (D)</p> Signup and view all the answers

What is the name of the mutation caused by purine to purine change?

<p>Transition mutation (D)</p> Signup and view all the answers

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