Podcast
Questions and Answers
Who first discovered the genetic role of DNA?
Who first discovered the genetic role of DNA?
- Frederick Griffith (correct)
- Gregor Mendel
- Dr. Sahar Jaffal
- Someone unknown
What is transformation in the context of Griffith's research?
What is transformation in the context of Griffith's research?
- Change in behavior of viruses
- Change in the chemical composition of bacteria
- Change in the shape of bacteria
- Change in genotype and phenotype due to assimilation of foreign DNA (correct)
What are bacteriophages?
What are bacteriophages?
- Bacteria that infect viruses
- Bacterial cells
- Proteins found in viruses
- Viruses that infect bacteria (correct)
What is the protective coat of a virus called?
What is the protective coat of a virus called?
What did Griffith mix with living cells of the harmless bacterium to observe transformation?
What did Griffith mix with living cells of the harmless bacterium to observe transformation?
What did Alfred Hershey and Martha Chase demonstrate in their experiment?
What did Alfred Hershey and Martha Chase demonstrate in their experiment?
According to Chargaff's rules, what is the relationship between the number of A and T bases, and the number of G and C bases in any species?
According to Chargaff's rules, what is the relationship between the number of A and T bases, and the number of G and C bases in any species?
What did Rosalind Franklin's X-ray crystallographic images of DNA allow James Watson to deduce?
What did Rosalind Franklin's X-ray crystallographic images of DNA allow James Watson to deduce?
In the Watson-Crick model, how do adenine (A) and thymine (T) form pairs?
In the Watson-Crick model, how do adenine (A) and thymine (T) form pairs?
What does DNA replication ensure?
What does DNA replication ensure?
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Study Notes
Discoverers of DNA's Genetic Role
- Frederick Griffith first discovered the genetic role of DNA through his transformation experiment.
Transformation in Griffith's Research
- Transformation is the process of altering the genetic material of a cell, which Griffith demonstrated by mixing a heat-killed virulent bacterium with living cells of a harmless bacterium.
Bacteriophages
- Bacteriophages are viruses that infect bacteria.
Virus Structure
- The protective coat of a virus is called a capsid.
Griffith's Transformation Experiment
- Griffith mixed heat-killed virulent bacteria with living cells of the harmless bacterium to observe transformation.
Hershey-Chase Experiment
- Alfred Hershey and Martha Chase demonstrated that DNA is the genetic material of a virus, not its protein coat.
Chargaff's Rules
- According to Chargaff's rules, the number of A and T bases in a DNA molecule is equal to the number of G and C bases in any species.
Rosalind Franklin's Contribution
- Rosalind Franklin's X-ray crystallographic images of DNA allowed James Watson to deduce the double helix structure of DNA.
Watson-Crick Model
- In the Watson-Crick model, adenine (A) and thymine (T) form pairs through hydrogen bonding, with A always pairing with T.
DNA Replication
- DNA replication ensures that the genetic information is duplicated accurately and passed on to the next generation.
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