Diuretics: Pharmacology Overview

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10 Questions

What is the primary mechanism of action of diuretics in lowering blood pressure?

Reducing blood volume through urinary excretion of water and electrolytes

Which class of diuretics works in the distal tubule of the nephron?

Thiazide diuretics

What is the prototype drug for potassium-sparing diuretics?

Spironolactone

Which class of drugs inhibits the conversion of angiotensin I to angiotensin II, thereby reducing blood pressure?

Angiotensin-converting enzyme (ACE) inhibitors

What is the primary mechanism of action of angiotensin II receptor blockers (ARBs) in lowering blood pressure?

Blocking the binding of angiotensin II to its receptors

Which class of antihypertensive drugs acts by blocking calcium ion channels in vascular smooth muscle cells?

Calcium channel blockers (CCBs)

What is the prototype drug for calcium channel blockers that acts primarily on arterioles?

Nifedipine

Which class of antihypertensive drugs is typically prescribed for patients who cannot tolerate ACE inhibitors?

Angiotensin II receptor blockers (ARBs)

Which adverse effect is commonly associated with the use of ACE inhibitors?

Persistent dry cough

Which nursing consideration is important when administering loop diuretics like furosemide?

Monitor fluid intake and electrolyte levels

Learn about diuretics, the first line drugs for managing hypertension. Explore the mechanisms of action of thiazide and potassium-sparing diuretics, their prototypes, common adverse effects, and nursing considerations during administration.

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