Diuretics: Pharmacology Overview

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Questions and Answers

What is the primary mechanism of action of diuretics in lowering blood pressure?

  • Inhibiting angiotensin II receptor binding
  • Inhibiting the renin-angiotensin-aldosterone system
  • Reducing blood volume through urinary excretion of water and electrolytes (correct)
  • Blocking calcium ion channels

Which class of diuretics works in the distal tubule of the nephron?

  • Loop diuretics
  • Thiazide diuretics (correct)
  • Potassium-sparing diuretics
  • Carbonic anhydrase inhibitors

What is the prototype drug for potassium-sparing diuretics?

  • Hydrochlorothiazide
  • Spironolactone (correct)
  • Furosemide
  • Enalapril

Which class of drugs inhibits the conversion of angiotensin I to angiotensin II, thereby reducing blood pressure?

<p>Angiotensin-converting enzyme (ACE) inhibitors (B)</p> Signup and view all the answers

What is the primary mechanism of action of angiotensin II receptor blockers (ARBs) in lowering blood pressure?

<p>Blocking the binding of angiotensin II to its receptors (D)</p> Signup and view all the answers

Which class of antihypertensive drugs acts by blocking calcium ion channels in vascular smooth muscle cells?

<p>Calcium channel blockers (CCBs) (A)</p> Signup and view all the answers

What is the prototype drug for calcium channel blockers that acts primarily on arterioles?

<p>Nifedipine (B)</p> Signup and view all the answers

Which class of antihypertensive drugs is typically prescribed for patients who cannot tolerate ACE inhibitors?

<p>Angiotensin II receptor blockers (ARBs) (A)</p> Signup and view all the answers

Which adverse effect is commonly associated with the use of ACE inhibitors?

<p>Persistent dry cough (B)</p> Signup and view all the answers

Which nursing consideration is important when administering loop diuretics like furosemide?

<p>Monitor fluid intake and electrolyte levels (A)</p> Signup and view all the answers

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