Patho Exam 3 Quiz 1
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Questions and Answers

Which of the following is the MOST common cause of a hypertensive emergency?

  • Acute myocardial infarction
  • Uncontrolled diabetes
  • Abrupt discontinuation of antihypertensive medications (correct)
  • Severe renal impairment

What is the PROTOTYPE drug for alpha-1 adrenergic antagonists (alpha-1 blockers)?

  • Metoprolol
  • Nitroprusside
  • Atenolol
  • Doxazosin (correct)

What is the MAIN mechanism of action for HMG-CoA reductase inhibitors (statins)?

  • Inhibit the enzyme HMG-CoA reductase (correct)
  • Activate the enzyme lipoprotein lipase
  • Increase HDL levels
  • Bind to bile acids and increase their excretion

What is the MAIN adverse effect associated with cardiac glycosides like digoxin?

<p>Ventricular dysrhythmias (D)</p> Signup and view all the answers

Which of the following is a common NURSING CONSIDERATION when administering beta-blockers?

<p>Both a and c (A)</p> Signup and view all the answers

What is the MAIN mechanism of action for bile acid sequestrants?

<p>Binding to bile acids and increasing their excretion (A)</p> Signup and view all the answers

What is the HALF-LIFE of the prototype drug for hypertensive emergencies, nitroprusside?

<p>2 minutes (A)</p> Signup and view all the answers

What is the THERAPEUTIC CLASS of fibric acid agents like gemfibrozil?

<p>Antihyperlipidemic (B)</p> Signup and view all the answers

Which of the following is a THERAPEUTIC CLASS for beta-blockers?

<p>Both b and c (D)</p> Signup and view all the answers

What is the MAIN ADVERSE EFFECT associated with phosphodiesterase inhibitors like milrinone?

<p>Ventricular dysrhythmia (C)</p> Signup and view all the answers

Which diuretic works in the distal tubule and is classified as a thiazide?

<p>Hydrochlorothiazide (C)</p> Signup and view all the answers

What is the PROTOTYPE drug for potassium-sparing diuretics that works in the collecting duct?

<p>Spironolactone (D)</p> Signup and view all the answers

Which diuretic works in the loop of Henle and is known for its fast-acting nature?

<p>Furosemide (C)</p> Signup and view all the answers

Which class of drugs inhibits angiotensin-converting enzyme (ACE) to reduce blood pressure?

<p>ACE Inhibitors (B)</p> Signup and view all the answers

Which group of drugs is characterized by names ending in '-prils'?

<p>ACE Inhibitors (B)</p> Signup and view all the answers

'Losartan' is a prototype drug belonging to which class of antihypertensive medications?

<p>Angiotensin II Receptor Blockers (D)</p> Signup and view all the answers

'Nifedipine' primarily acts on which type of blood vessels?

<p>Arterioles (C)</p> Signup and view all the answers

'Hydrochlorothiazide' is associated with what adverse effect among others?

<p>Dehydration and loss of electrolytes (A)</p> Signup and view all the answers

'Diltiazem' produces vasodilation primarily in which type of blood vessels?

<p>Arterioles (C)</p> Signup and view all the answers

Which diuretic blocks aldosterone and works in the collecting duct at the end of the nephron?

<p>Hydrochlorothiazide (C)</p> Signup and view all the answers

Which of the following is a contraindication for the use of low molecular weight heparins?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary action of low molecular weight heparins?

<p>Prevent clotting by activating antithrombin (B)</p> Signup and view all the answers

Which of the following is a potential adverse effect of low molecular weight heparins?

<p>Both b and c (C)</p> Signup and view all the answers

Which of the following is a nursing consideration for the administration of low molecular weight heparins?

<p>All of the above (D)</p> Signup and view all the answers

What is the treatment for overdose of low molecular weight heparins?

<p>Protamine sulfate (B)</p> Signup and view all the answers

Which of the following is a pharmacologic class of oral anticoagulants?

<p>Vitamin K antagonists (B)</p> Signup and view all the answers

What is the primary action of vitamin K antagonists like warfarin?

<p>Inhibit the action of vitamin K, thereby diminishing the synthesis of clotting factors II, VII, IX, and X (C)</p> Signup and view all the answers

Which of the following is a potential adverse effect of vitamin K antagonists like warfarin?

<p>Both b and c (D)</p> Signup and view all the answers

What is a contraindication for the use of vitamin K antagonists like warfarin?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is an interaction that should be considered when administering vitamin K antagonists like warfarin?

<p>All of the above (D)</p> Signup and view all the answers

What is a key nursing consideration for patients taking herbals like ginkgo, garlic, and ginger?

<p>Monitor INR levels (A)</p> Signup and view all the answers

What is the pregnancy category for herbals like ginkgo, garlic, and ginger?

<p>Category X (B)</p> Signup and view all the answers

Which drug directly inhibits thrombin to prevent thrombus development?

<p>Dabigatran (B)</p> Signup and view all the answers

What is a common adverse effect of antiplatelet drugs like Clopidogrel?

<p>Gastric bleeding (B)</p> Signup and view all the answers

Which class of drugs acts by blocking glycoprotein IIB/IIIA receptor to prevent platelet activation?

<p>Glycoprotein IIB/IIIA receptor antagonists (B)</p> Signup and view all the answers

When is the best time to administer thrombolytics like Alteplase?

<p>Within 4 hours of clot formation (B)</p> Signup and view all the answers

What is the main action of hemostatics like Aminocaproic Acid?

<p>Shorten bleeding time (B)</p> Signup and view all the answers

Which drug is a direct inhibitor of factor Xa?

<p>Rivaroxaban (D)</p> Signup and view all the answers

'Acts by binding irreversibly to COX in platelets' describes the mechanism of action of which drug?

<p>'Aspirin' (C)</p> Signup and view all the answers

What interaction should be monitored in patients taking Aminocaproic Acid?

<p>Interactions with estrogens and oral contraceptives (C)</p> Signup and view all the answers

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