Podcast
Questions and Answers
What is the primary purpose of using diuretics in animals?
What is the primary purpose of using diuretics in animals?
- To remove extra water volume in animals with edema or volume overload (correct)
- To induce beneficial hemodynamic effects before the onset of diuresis
- To correct specific ion imbalances
- To increase blood pressure and pulmonary capillary wedge pressure
Which diuretic class inhibits the reabsorption of sodium and chloride in the thick, ascending loop of Henle?
Which diuretic class inhibits the reabsorption of sodium and chloride in the thick, ascending loop of Henle?
- Carbonic anhydrase inhibitors
- Thiazides
- Potassium-sparing diuretics
- Loop diuretics (correct)
What is the potential consequence of combining diuretics from different classes?
What is the potential consequence of combining diuretics from different classes?
- Maximal response within a class
- Decreased renal perfusion
- Increased fluid retention
- Additive and potentially synergistic effects (correct)
What is the role of renal vasodilation induced by furosemide?
What is the role of renal vasodilation induced by furosemide?
What is the duration of diuretic action of furosemide after IV administration?
What is the duration of diuretic action of furosemide after IV administration?
What is the percentage of protein binding for furosemide?
What is the percentage of protein binding for furosemide?
What is the clearance route of furosemide from the body?
What is the clearance route of furosemide from the body?
What is the bioavailability of oral furosemide in small animals?
What is the bioavailability of oral furosemide in small animals?
In which patients might higher-than-normal doses of furosemide be required?
In which patients might higher-than-normal doses of furosemide be required?
What is the major adverse effect from acute administration of large doses of furosemide?
What is the major adverse effect from acute administration of large doses of furosemide?
Which type of diuretic is torsemide?
Which type of diuretic is torsemide?
What happens to the efficacy of furosemide after 14 days of repeated administration?
What happens to the efficacy of furosemide after 14 days of repeated administration?
Which diuretics act on the proximal portion of the distal convoluted tubule to inhibit sodium reabsorption?
Which diuretics act on the proximal portion of the distal convoluted tubule to inhibit sodium reabsorption?
Which diuretics decrease the renal excretion of calcium?
Which diuretics decrease the renal excretion of calcium?
Which drug interaction is a concern when administering furosemide?
Which drug interaction is a concern when administering furosemide?
Which potassium-sparing diuretic is most frequently used in veterinary medicine?
Which potassium-sparing diuretic is most frequently used in veterinary medicine?
What is the primary function of aldosterone in the renal tubules?
What is the primary function of aldosterone in the renal tubules?
Why is spironolactone not recommended as monotherapy for heart failure?
Why is spironolactone not recommended as monotherapy for heart failure?
What is the primary mode of action of carbonic anhydrase inhibitors?
What is the primary mode of action of carbonic anhydrase inhibitors?
What is the preferred route of administration for DMSO in large animals?
What is the preferred route of administration for DMSO in large animals?
What is a potential consequence of administering repeated doses of mannitol?
What is a potential consequence of administering repeated doses of mannitol?
Which system is activated in response to hyponatremia, hyperkalemia, and decreases in blood pressure or cardiac output?
Which system is activated in response to hyponatremia, hyperkalemia, and decreases in blood pressure or cardiac output?
What is the primary function of spironolactone at its receptor site?
What is the primary function of spironolactone at its receptor site?
Why should spironolactone not be administered concurrently with potassium supplements?
Why should spironolactone not be administered concurrently with potassium supplements?
