Diuretics and Natriuretic Substances in Renal Physiology
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Questions and Answers

Where are most clinically useful diuretics transported from the blood to their active sites?

  • Renal papilla
  • Interstitial space of the nephron
  • Glomerular capsule
  • Luminal surface of tubular segments (correct)

What is the function of the thick ascending limb of the loop of Henle?

  • Reabsorption of water by osmotic forces
  • Selective reabsorption of glucose and amino acids
  • Excretion of potassium and divalent ions
  • Active cotransport of sodium-potassium chlorides (correct)

Which functional zone along the nephron is responsible for reabsorbing sodium bicarbonate, sodium chloride, glucose, and amino acids?

  • Ascending loop of Henle
  • Proximal convoluted tubule (correct)
  • Distal convoluted tubule
  • Descending loop of Henle

What percentage of Na and water reabsorption occurs in the early proximal tubule?

<p>67% (D)</p> Signup and view all the answers

What is the main function of the distal tubule in terms of sodium chloride reabsorption?

<p>Reabsorbs about 10% of filtered sodium chloride via a Na/Cl- transporter sensitive to thiazide diuretics (D)</p> Signup and view all the answers

Diuretics are drugs that increase the rate of ______ formation

<p>urine</p> Signup and view all the answers

The kidney regulates the ionic composition and volume of urine by the reabsorption or secretion of ions and/or water at five functional zones along the ______

<p>nephron</p> Signup and view all the answers

Sodium bicarbonate, sodium chloride, glucose, amino acids, and other organic solutes are reabsorbed via specific transport systems in the early proximal ______

<p>tubule</p> Signup and view all the answers

Water is reabsorbed from the thin descending limb by osmotic forces generated in the hypertonic medullary ______

<p>interstitium</p> Signup and view all the answers

About 10% of the filtered sodium chloride is reabsorbed via a Na/Cl - transporter, which is sensitive to ______ diuretics

<p>thiazide</p> Signup and view all the answers

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