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Diuretics and Carbonic Anhydrase Inhibitors Overview
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Diuretics and Carbonic Anhydrase Inhibitors Overview

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Questions and Answers

What is the primary effect of diuretics on urine flow?

  • Increase in K+ reabsorption
  • Decrease in Cl- excretion
  • Increase in Na+ excretion (correct)
  • Decrease in urine volume

    • Where does Carbonic Anhydrase Inhibitors primarily act in the nephron?

  • PCT (correct)
  • DCT
  • Collecting Duct
  • Loop of Henle

    • What is the effect of Carbonic Anhydrase Inhibitors on urinary HCO-3 excretion?

  • Decreased urinary HCO-3 excretion
  • Rapid rise in urinary HCO-3 excretion (correct)
  • No effect on urinary HCO-3 excretion
  • Increased GFR

    • Which condition is NOT a therapeutic use of Carbonic Anhydrase Inhibitors?

    <p>Hypertension</p> Signup and view all the answers

    What is one of the other actions of Carbonic Anhydrase inhibitors besides their diuretic effect?

    <p>CNS paresthesia and somnolence</p> Signup and view all the answers

    What is the recommended treatment for resistance to Diuretic Monotherapy?

    <p>Acetazolamide + HCTZ</p> Signup and view all the answers

    What is the primary mechanism of action of carbonic anhydrase inhibitors?

    <p>Inhibition of carbonic anhydrase in the renal tubules</p> Signup and view all the answers

    What is the effect of carbonic anhydrase inhibitors on the fractional excretion of potassium?

    <p>Increase by 70%</p> Signup and view all the answers

    Which of the following is a therapeutic use of carbonic anhydrase inhibitors?

    <p>Treatment of glaucoma</p> Signup and view all the answers

    What is a potential adverse effect of carbonic anhydrase inhibitors?

    <p>Drowsiness and paresthesia</p> Signup and view all the answers

    Which of the following is a contraindication for the use of carbonic anhydrase inhibitors?

    <p>Hypercapnic respiratory failure</p> Signup and view all the answers

    What is the effect of carbonic anhydrase inhibitors on the GFR (glomerular filtration rate)?

    <p>Decrease</p> Signup and view all the answers

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