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Diuretics and Carbonic Anhydrase Inhibitors Overview

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Diuretics and Carbonic Anhydrase Inhibitors Overview

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Questions and Answers

What is the primary effect of diuretics on urine flow?

Increase in K+ reabsorption

Decrease in Cl- excretion

Increase in Na+ excretion (correct)

Decrease in urine volume

Where does Carbonic Anhydrase Inhibitors primarily act in the nephron?

PCT (correct)

DCT

Collecting Duct

Loop of Henle

What is the effect of Carbonic Anhydrase Inhibitors on urinary HCO-3 excretion?

Decreased urinary HCO-3 excretion

Rapid rise in urinary HCO-3 excretion (correct)

No effect on urinary HCO-3 excretion

Increased GFR

Which condition is NOT a therapeutic use of Carbonic Anhydrase Inhibitors?

Hypertension (B) Signup and view all the answers

What is one of the other actions of Carbonic Anhydrase inhibitors besides their diuretic effect?

CNS paresthesia and somnolence (A) Signup and view all the answers

What is the recommended treatment for resistance to Diuretic Monotherapy?

Acetazolamide + HCTZ (B) Signup and view all the answers

What is the primary mechanism of action of carbonic anhydrase inhibitors?

Inhibition of carbonic anhydrase in the renal tubules (A) Signup and view all the answers

What is the effect of carbonic anhydrase inhibitors on the fractional excretion of potassium?

Increase by 70% (A) Signup and view all the answers

Which of the following is a therapeutic use of carbonic anhydrase inhibitors?

Treatment of glaucoma (C) Signup and view all the answers

What is a potential adverse effect of carbonic anhydrase inhibitors?

Drowsiness and paresthesia (A) Signup and view all the answers

Which of the following is a contraindication for the use of carbonic anhydrase inhibitors?

Hypercapnic respiratory failure (B) Signup and view all the answers

What is the effect of carbonic anhydrase inhibitors on the GFR (glomerular filtration rate)?

Decrease (B) Signup and view all the answers