Diseases of Oral Cavity & Esophagus
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Which of the following tumors is classified as malignant from the odontogenic epithelium category?

  • Ameloblastic carcinoma (correct)
  • Odontogenic fibroma
  • Calcifying epithelial odontogenic tumor
  • Compounded odontoma
  • What is the most common inflammatory lesion of the salivary gland?

  • Mucocoele (correct)
  • Viral sialadenitis
  • Sialolithiasis
  • Parotitis
  • Which type of odontogenic tumor is considered a hamartoma rather than a true neoplasm?

  • Ameloblastic fibroma
  • Odontoma (correct)
  • Clear cell odontogenic carcinoma
  • Ameloblastoma
  • Which major salivary gland is not involved in the formation of mucoceles?

    <p>Minor salivary glands</p> Signup and view all the answers

    What distinguishes ameloblastic fibrosarcoma from other tumors in the odontogenic epithelium and ectomesenchyme category?

    <p>It is a malignant variant</p> Signup and view all the answers

    Which virus is primarily responsible for most orofacial herpes infections?

    <p>HSV-1</p> Signup and view all the answers

    What is a distinguishing feature of oral candidiasis?

    <p>White patches that are easily detached</p> Signup and view all the answers

    What condition is associated with a beefy-red tongue and atrophy of papillae?

    <p>Glossitis</p> Signup and view all the answers

    Which oral manifestation is seen in immunocompromised patients, particularly those with HIV?

    <p>Hairy leukoplakia</p> Signup and view all the answers

    What characterizes the oral manifestation of diphtheria?

    <p>Gray-white exudative membrane and lymph node enlargement</p> Signup and view all the answers

    Which of the following is NOT typically associated with apthous ulcers?

    <p>They are usually painless</p> Signup and view all the answers

    Which systemic condition is linked to an increased risk of opportunistic oral infections?

    <p>HIV infection</p> Signup and view all the answers

    What typically causes the oral manifestations of hairy leukoplakia?

    <p>Epstein-Barr virus</p> Signup and view all the answers

    Which type of salivary gland tumor is most commonly associated with a higher likelihood of malignancy?

    <p>Mucoepidermoid tumor</p> Signup and view all the answers

    What is the primary characteristic of a Warthin tumor?

    <p>Rounded mass with cleft-like spaces</p> Signup and view all the answers

    What symptom is most commonly associated with esophageal stenosis?

    <p>Dysphagia</p> Signup and view all the answers

    Which of the following tumors is most likely to recur after enucleation?

    <p>Pleomorphic adenoma</p> Signup and view all the answers

    Which condition is characterized by a failure of the esophagus to relax?

    <p>Achalasia</p> Signup and view all the answers

    What is one of the main associations of Plummer-Vinson syndrome?

    <p>Mucosal rings and webs</p> Signup and view all the answers

    Which bacterial infection is commonly associated with parotid sialadenitis?

    <p>Staphylococcus and Streptococcus</p> Signup and view all the answers

    Which characteristic describes the malignant transformation of a pleomorphic adenoma?

    <p>Aggressive malignant mixed tumor</p> Signup and view all the answers

    What is the main characteristic that defines leukoplakia?

    <p>A white patch that cannot be scraped off</p> Signup and view all the answers

    Which of the following associations is most commonly linked to squamous cell carcinoma of the oral cavity?

    <p>Chewing betel quid</p> Signup and view all the answers

    Erythroplakia is generally regarded as more serious than leukoplakia because it indicates:

    <p>Higher likelihood of dysplasia or cancer</p> Signup and view all the answers

    Which histological feature is often observed in squamous cell carcinoma?

    <p>Well-differentiated squamous cells</p> Signup and view all the answers

    What percentage of leukoplakic lesions are estimated to be premalignant?

    <p>Between 5% and 25%</p> Signup and view all the answers

    What type of tumor is primarily associated with odontogenic tissue?

    <p>Ameloblastoma</p> Signup and view all the answers

    What is a common site for squamous cell carcinoma in the oral cavity?

    <p>Floor of the mouth, tongue, and others</p> Signup and view all the answers

    Which feature distinguishes erythroplakia from other oral lesions?

    <p>It often shows dysplasia or early cancer</p> Signup and view all the answers

    What is the most important risk factor for developing esophageal adenocarcinoma?

    <p>Gastroesophageal reflux disease (GERD)</p> Signup and view all the answers

    Which condition is characterized by an outpouching that involves all layers of the esophagus?

    <p>Diverticulum</p> Signup and view all the answers

    What type of cancer is associated with long-standing use of corrosive agents and is known for early invasion due to rich lymphatic drainage?

    <p>Squamous cell carcinoma</p> Signup and view all the answers

    Which sign is indicative of reflux esophagitis?

    <p>Presence of eosinophils in epithelium</p> Signup and view all the answers

    What is a significant complication associated with esophageal varices?

    <p>Upper GI bleeding</p> Signup and view all the answers

    Which of the following histological features is seen in Barrett esophagus?

    <p>Gastric or intestinal type goblet cells</p> Signup and view all the answers

    Which type of esophageal cancer shows the highest association with dietary and environmental modifications, particularly in specific regions worldwide?

    <p>Squamous cell carcinoma</p> Signup and view all the answers

    What is a common complication of chronic gastroesophageal reflux disease leading to Barrett esophagus?

    <p>Chronic esophagitis</p> Signup and view all the answers

    What is the hallmark clinical presentation of squamous cell carcinoma of the esophagus?

    <p>Insidious onset of dysphagia</p> Signup and view all the answers

    Which oral manifestation is associated with scarlet fever?

    <p>Fiery red tongue with prominent papillae</p> Signup and view all the answers

    What clinical feature distinguishes lichen planus in the oral cavity?

    <p>Reticulate, lacelike white keratotic lesions</p> Signup and view all the answers

    Which statement is true regarding pemphigus and bullous pemphigoid?

    <p>Pemphigus lesions are differentiated histologically from those of bullous pemphigoid</p> Signup and view all the answers

    What is a significant risk factor for developing leukoplakia?

    <p>Tobacco use</p> Signup and view all the answers

    What oral condition is characterized by a friable, red, pyogenic granuloma during pregnancy?

    <p>Pregnancy tumor</p> Signup and view all the answers

    Which hematologic disorder may present with severe oral infections like gingivitis?

    <p>Pancytopenia</p> Signup and view all the answers

    How can erythroplakia be described clinically?

    <p>Red velvety erosions in the mucosa</p> Signup and view all the answers

    What genetic condition is associated with multiple aneurysmal telangiectasias in the oral cavity?

    <p>Rendu-Osler-Weber syndrome</p> Signup and view all the answers

    Study Notes

    Diseases of Oral Cavity & Esophagus

    • Oral cavity infections frequently involve herpes simplex virus (HSV-1).
    • Common orofacial herpes manifestations are mild cold sores.
    • Acute herpetic gingivostomatitis presents with vesicles and ulcers in the oral cavity.
    • Recurrent herpetic stomatitis is a recurring condition.
    • Apthous ulcers are common, superficial, and painful ulcerations of oral mucosa.
    • These sores tend to heal on their own but can recur.
    • Glossitis typically features a beefy-red tongue, resulting from vitamin B12 or iron deficiency.
    • Oral candidiasis (thrush) shows superficial white patches or a fluffy membrane.
    • This is caused by the fungus Candida, commonly found in the oral cavity.
    • Conditions like diabetes, immunocompromised states (e.g., HIV), and neutropenia increase the risk.

    Oral Manifestations of Systemic Disease

    • Hairy leukoplakia appears as white, fluffy thickenings on the tongue's sides, frequently in immunocompromised individuals (especially those with HIV).
    • Epstein-Barr virus is often associated with this.
    • Infections like measles (Koplik spots), infectious mononucleosis, and diphtheria can manifest in the oral cavity.
    • Dermatologic conditions like lichen planus, pemphigus, or erythema multiforme (including Stevens-Johnson syndrome) sometimes show oral manifestations.
    • Hematologic disorders such as pancytopenia and leukemia can cause oral infections and lesions that resemble those seen in pancytopenia.
    • Monocytic leukemia can cause infiltration and enlargement of the gingivae.

    Precancerous Lesions

    • Oral leukoplakia is a clinical term for white lesions that cannot be scraped off.
    • It's classified as precancerous unless proven otherwise.
    • Erythroplakia are less common, red, velvety lesions that can be more ominous and are linked to a higher risk of oral cancer.
    • Tobacco use (cigarettes, pipes, cigars, chewing tobacco) is a significant risk factor for both leukoplakia and erythroplakia, particularly for the latter.

    Tumors and Precancerous Lesions

    • Other tumors, such as papillomas, hemangiomas, and lymphomas, can also occur in the oral cavity, although less frequently and often not linked to precancerous conditions.
    • The most significant oral tumor is often squamous cell carcinoma (SCC).
    • SCC lesions develop frequently in areas of the mouth like the floor of the mouth, tongue, hard palate, and base of tongue.
    • Oral SCC often manifest as ulcerated or infiltrating lesions.

    Oral Cavity Squamous Cell Carcinoma

    • Smoking, tobacco, alcohol, and environmental elements often increase the risk of oral squamous cell carcinoma (OSCC).
    • OSCC spread to cervical, mediastinal lymph nodes, lungs, and liver.
    • OSCC is often classified according to the stage of dysplasia (mild, moderate, severe, or carcinoma in situ [CIS]) and the stage of invasion.

    Odontogenic Tumors

    • Odontogenic tumors are an assorted group of lesions classified according to origin (epithelial or ectomesenchymal or both).
    • They can be benign, malignant, or hamartomas.
    • The major groups include ameloblastoma, odontoma, odontogenic fibroma, odontogenic myxoma, and cementoblastoma.

    Diseases of Salivary Glands

    • Inflammations (siallinen), like mumps and autoimmune disorders like Sjogren's syndrome, typically affect the parotid gland.
    • Sialolithiasis (stones) can block salivary ducts.
    • Common benign tumors include pleomorphic adenomas (frequently seen in the parotid gland).
    • Other benign tumors (such as Warthin tumor) include epithelial and mesenchymal elements, with mixed appearance.
    • Malignant tumors, such as mucoepidermoid carcinomas and adenoid cystic carcinomas are observed in salivary glands.

    Diseases of Esophagus

    • Dysphagia, heartburn, pain, and hematemesis are common symptoms of esophageal diseases.
    • Congenital anomalies, infections, chemicals, motor function alterations, and varices can affect the esophagus.
    • Barrett's esophagus is an issue related to chronic gastroesophageal reflux (GERD) and subsequent esophageal changes.
    • There is a connection to adenocarcinoma, a type of esophageal cancer.
    • The esophageal squamous cell carcinoma is a common issue with various stages of involvement.

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    Oral Cavity and Esophagus PDF

    Description

    This quiz covers various diseases affecting the oral cavity and esophagus, including herpes simplex virus infections, apthous ulcers, and oral candidiasis. It also highlights the oral manifestations of systemic diseases, such as hairy leukoplakia in immunocompromised patients. Test your knowledge on these prevalent conditions and their clinical presentations.

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