55 Questions
refers to the PROGRESSION OF A DISEASE process in an individual over time, in the absence of treatment.
Natural history of disease
SAXITOXIN AND SIMILAR TOXINS FORM SHELLFISH ; few minutes– 30 minutes
Paralytic shellfish poisoning
NAUSEA, VOMITING, CRAMPS, HEADACHE, NERVOUSNESS, BLURRED VISION, CHEST PAIN, confusion, twitching, convulsions; few minutes–few hours.
Organophosphorusingestion
DIARRHEA, often with fever and cramps; usually 6–48 hours
Salmonella
SEVERE ACUTE RESPIRATORY SYNDROME (SARS); 3–10 days, usually 4–6 days
SARS-associated coronaviruses
CHICKENPOX; 10–21 days, usually 14–16 days
Varicella -zoster virus
SYPHILIS; 10–90 days, usually 3 weeks
Treponema pallidum
HEPATITIS; 14–50 days, average 4 weeks
Hepatitis A
HEPATITIS; 50–180 days, usually 2– 3 months
Hepatitis B
AIDS; <1 to 15+ year
Human immunodeficiency virus
LEUKEMIA; 2-12 years
Atomic bomb radiation (Japan)
THYROID CANCER; 3–20+ years
Radiation (Japan, Chernobyl)
BONE MARROW; 8–40 years
Radium (watch dial painters
refers to the PROPORTION OF EXPOSED PERSONS who become infected.
Infectivity
refers to the proportion of infected individuals who develop clinically apparent disease
Pathogenicity
refers to the proportion of clinically apparent CASES THAT ARE SEVERE OR FATAL
Virulence
Such PERSONS WHO ARE INFECTIOUS but have subclinical disease; are persons with incubating disease or inapparent infection
Carriers
a SINGLE INSTANCE OF DISEASE, injury, or other health condition that meets selected criteria of clinical and laboratory findings and for person, place, and time.
Case
refers to a DISEASE that occurs INFREQUENTLY and IRREGULARLY.
Sporadic
refers to the constant presence and/or usual prevalence of a disease or infectious agent in a POPULATION WITHIN A GEOGRAPHIC AREA.
Endemic
refers to PERSISTENT, HIGH LEVELS OF DISEASE OCCURRENCE
Hyperendemic
An observed amount of disease that is USUALLY PRESENT IN A COMMUNITY OR GEOGRAPHIC LOCATION, like a state or country, known through historical counts or public health surveillance, and often used for comparison in identifying outbreaks or measuring the effectiveness of public health actions.
Expected level
refers to an INCREASE, OFTEN SUDDEN, IN A NUMBER OF CASES of a disease above what is normally expected in that population in that area.
Epidemic
carries the SAME DEFINITION OF EPIDEMIC, but is often used for a more limited geographic area.
Outbreak
A group of cases of the same general health problem that occur in a LIMITED GEOGRAPHICAL AREA without regard to the expected levels.
Cluster
refers to an epidemic that has spread over several countries or continents, usually affecting a large number of people
Pandemic
A virus that has not been seen before or is a virus that is known but has not infected humans before
Novel virus
What is NERD?
Novel Emerging Respiratory Disease
A fictional novel emerging respiratory disease caused by a virus that can spread from person to person
NERD
when an agent and susceptible hosts are present in adequate numbers, and the agent can be effectively conveyed from a source to the susceptible hosts.
Epidemic
Transmission occurs from person to person.
propagated source
patients are exposed to the source of the disease at irregular intervals
Intermittent common source outbreak
both common-source epidemics and propagated epidemics.
Mixed epidemics
The disease is spreading from person to person with confirmed outbreaks at the community level.
Phase 4
There are scattered cases or small clusters of disease in humans. If the illness is spreading from human to human, it’s not broad enough to cause community-level outbreaks
Phase 3
A virus in animals has caused no known infections in humans.
Phase 1
An animal virus has caused infection in humans.
Phase 2
The disease is spreading between humans in more than one country of one of the WHO regions.
Phase 5
At least one more country, in a different region from Phase 5, has community-level outbreaks.
Phase 6
List of the deadliest pandemics in world history includes:
The black death; The influenza pandemic of 1918; Smallpox; HIV and AIDS; COVID19
A bacterial infection found mainly in rodents and associated fleas, plague readily leaps to humans in close contact.
black death
most nutorious epedimic in history
Black Death
3 types of Plague
Bubonic plague, Pneumonic plague, Septicemic plague
the disease's most common form, refers to telltale buboes—painfully swollen lymph nodes—that appear around the groin, armpit, or neck.
Bubonic Plague
the most infectious type, is an advanced stage of plague that moves into the lungs
Pneumonic Plague
Patients develop fever, chills, extreme weakness, abdominal pain, shock, and possibly bleeding into the skin and other organs.
Septicemic plague
It was caused by an H1N1 virus with genes of avian origin.
Spanish Flu
also known as the influenza pandemic of 1918
Spanish Flu
caused by variola virus
Smallpox
The most severe phase of HIV infection.
AIDS
Some people have flu-like symptoms.
Acute HIV Infection
called asymptomatic HIV infection or clinical latency. any symptoms or get sick during this phase
Chronic HIV Infection
is a sickness caused by a virus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
COVID19
Treatment of Covid 19
Nirmatrelvir, Remdesivir, Molnupiravir
COVOID VACCINES
Test your knowledge on the natural progression of a disease in an individual over time, without any treatment. Explore the factors and stages involved in the development of a disease without intervention.
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