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Discovery of New Antibiotics - Dr. Faiza Nadeem Health Biotechnology BT-502 (2021)

10 Questions

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Discovery of New Antibiotics - Dr. Faiza Nadeem Health Biotechnology BT-502 (2021)

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Questions and Answers

What term is used to describe the concentration of drug required to inhibit or kill a microorganism being greater than normal use?

Superbug development

Therapeutics

Antibiotic misuse

Antibiotic resistance (correct)

In 1945, what percentage of resistance to penicillin in Staphylococcus aureus was identified?

50% (correct)

75%

25%

100%

Which biochemical mechanism of resistance involves producing an enzyme that inactivates the antibiotic?

Quorum sensing

Modification/protection of the target site

Efflux pumps and outer membrane permeability

Use of alternative pathways for metabolic/growth requirements (correct)

What term is used to describe harmless bacteria developing resistance to multiple antibiotics and causing life-threatening infections?

Superbug development Signup and view all the answers

Who first coined the word 'antibiotics' in 1942?

Selman Waksman Signup and view all the answers

What is the major mechanism for resistance in Tetracycline?

Efflux Pumps Signup and view all the answers

How do bacteria resist trimethoprim and sulphonamides?

By producing enzymes that inactivate the antibiotics Signup and view all the answers

What is the main role of quorum sensing in bacteria?

Coordinate gene expression for virulence, conjugation, apoptosis, mobility and resistance Signup and view all the answers

Which mechanism causes resistance to chloramphenicol in bacteria?

Inactivation of Chloramphenicol by chloramphenicol acetyltransferase Signup and view all the answers

What is the purpose of producing alternative penicillin binding proteins in MRSA?

To survive by adopting the role of a native protein Signup and view all the answers