Microbiology of Upper Respiratory Tract

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Which part of the respiratory tract is characterized by the presence of hyaline cartilage plates?

Trachea

What type of epithelium is typically found in the conducting zone of the respiratory tract?

Pseudostratified ciliated columnar epithelium

Which respiratory zone structure is associated with gas exchange in the lungs?

Alveoli

What happens to cilia along the path from the conducting zone to the respiratory zone?

They become non-functional

Which type of bacteria are commonly found in the upper respiratory tract microbiome?

Haemophilus influenzae

Which respiratory tract region is involved in warming and moistening incoming air?

Trachea

What happens to mucous along the path from the conducting to the respiratory zone?

It decreases and eventually disappears

What is the significance of the optimal receptor binding temperature for rhinovirus to ICAM-1?

It affects the immunogenicity of the virus

Why must rhinovirus be less immunogenic due to the way it binds to ICAM-1?

To evade the host immune system effectively

What are the common signs and symptoms of a rhinovirus infection?

Sneezing and runny nose

How does rhinovirus enter the host cell?

Endocytosis via binding to ICAM-1

What is the role of ICAM-1 in the attachment and entry of rhinovirus into the host cell?

Assisting in endocytosis of the virus

Why does the attachment of rhinoviruses to ICAM-1 make them less immunogenic?

It shields viral proteins from immune recognition

Explain why rhinoviruses are classified as picornaviruses.

Their RNA genome is single-stranded.

Which of the following bacteria found in the upper respiratory tract is Gram-negative and requires both hemin and NAD+ to live?

Haemophilus influenzae

Which bacterium found in the upper respiratory tract is known for its ability to break down lactate into ATP and nitrate into nitric oxide?

Veillonella

Among the bacteria mentioned, which one is known for causing conditions like sepsis, pneumonia, toxic shock, and pimples?

Streptococcus aureus

Which of the following is true about Propionibacterium acnes?

It lowers skin pH.

Which bacteria found in the upper respiratory tract is referred to as fastidious, meaning it is difficult to grow in laboratory conditions?

Haemophilus influenzae

Which bacterium found in the upper respiratory tract can be categorized as facultative anaerobic and known for causing meningitis?

Haemophilus influenzae

Which bacterium found in the upper respiratory tract resembles the bacteria responsible for causing diphtheria but does not actually cause the disease?

Propionibacterium acnes

Which of the following bacteria found in the upper respiratory tract is known for its ability to break down nitrate oxide and nitrate into ATP?

Veillonella

What is the initial step in Rhinovirus replication?

Binding to ICAM-1

Which process dissolves the capsid of Rhinoviruses during replication?

Endocytosis

How do Rhinoviruses exit the host cell after assembly?

Lysis

What is the effect of HRV infections on one's susceptibility to bacteria?

Increases susceptibility

How do HRV infections affect tight junctions in the body?

Disrupt them

Which virus cause lysis of host cell?

Adenovirus

Epstein barr virus is the causative agent of Mononucleosis

True

Prevention of Mono is impossible

True

Learn about the diagnosis and treatment of diphtheria, symptoms of the common cold, and the definition of rhinovirus. Explore the signs and symptoms of the common cold, including sneezing, congestion, sore throat, and more.

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