Podcast
Questions and Answers
Qual classe pertenece diltiazem (Cardizem)?
Qual classe pertenece diltiazem (Cardizem)?
Qual es el mecanismo de acción de diltiazem (Cardizem)?
Qual es el mecanismo de acción de diltiazem (Cardizem)?
- Bloquear la inflow de iones de Ca en el músculo cardíaco
- Vasodilatador A y V
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- precarga y postcarga
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- demanda de O2 miocárdico
Quais son las indicaciones para diltiazem (Cardizem)?
Quais son las indicaciones para diltiazem (Cardizem)?
A-fib/flutter con tasas ventriculares rápidas
Quais son las contraindicaciones para diltiazem (Cardizem)?
Quais son las contraindicaciones para diltiazem (Cardizem)?
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Quais son algumas reacciones adversas de diltiazem (Cardizem)?
Quais son algumas reacciones adversas de diltiazem (Cardizem)?
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Quais son las interacciones medicamentosas de diltiazem (Cardizem)?
Quais son las interacciones medicamentosas de diltiazem (Cardizem)?
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Qual es la dosis recomendada para diltiazem (Cardizem) en adultos?
Qual es la dosis recomendada para diltiazem (Cardizem) en adultos?
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Es diltiazem (Cardizem) recomendado en pacientes pediátricos?
Es diltiazem (Cardizem) recomendado en pacientes pediátricos?
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Qual es el inicio y duración de diltiazem (Cardizem)?
Qual es el inicio y duración de diltiazem (Cardizem)?
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Quais son algunas consideraciones especiales para diltiazem (Cardizem)?
Quais son algunas consideraciones especiales para diltiazem (Cardizem)?
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Study Notes
Diltiazem (Cardizem) Overview
- Diltiazem class: Calcium channel blocker, used to manage cardiovascular conditions.
Mechanism of Action
- Blocks calcium ion influx into cardiac muscle, reducing contractility.
- Acts as both atrial and ventricular vasodilator.
- Increases preload and afterload, while decreasing myocardial oxygen demand.
Indications
- Primarily indicated for atrial fibrillation or flutter with rapid ventricular rates.
Contraindications
- Not recommended in patients with wide-complex tachycardia.
- Avoid in individuals with sick sinus syndrome.
- Contraindicated during cardiogenic shock.
Adverse Reactions
- Common side effects include flushing and headache.
- May cause bradycardia and hypotension in some patients.
Drug Interactions
- Careful use with digoxin, as it can increase the risk of toxicity.
- Interaction potential exists with beta blockers, requiring monitoring.
Dosage for Adults
- Initial IV dose: 0.25 mg/kg (average 20 mg) administered over two minutes.
- May repeat bolus after 15 minutes if needed.
- Alternative dosing of 0.35 mg/kg IV also available, given over two minutes.
Dosage for Pediatrics
- Diltiazem use in pediatric populations is not recommended.
Duration of Action
- Onset of action occurs within 2-5 minutes.
- Peak effects are variable, with overall duration lasting 1-3 hours.
Special Considerations
- Classified as pregnancy safety category C, indicating potential risks.
- Use cautiously in patients with pre-existing renal or hepatic dysfunction.
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Description
Este quiz aborda diltiazem (Cardizem), un medicamento utilizado como bloqueador de canales de calcio. Aspera tópicos como su mecanismo de acción, indicaciones y contraindicaciones, proporcionando un marco útil para estudiantes de farmacología.
