Questions and Answers
Qual classe pertenece diltiazem (Cardizem)?
Qual es el mecanismo de acción de diltiazem (Cardizem)?
- Bloquear la inflow de iones de Ca en el músculo cardíaco
- Vasodilatador A y V
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- precarga y postcarga
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- demanda de O2 miocárdico
Quais son las indicaciones para diltiazem (Cardizem)?
A-fib/flutter con tasas ventriculares rápidas
Quais son las contraindicaciones para diltiazem (Cardizem)?
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Quais son algumas reacciones adversas de diltiazem (Cardizem)?
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Quais son las interacciones medicamentosas de diltiazem (Cardizem)?
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Qual es la dosis recomendada para diltiazem (Cardizem) en adultos?
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Es diltiazem (Cardizem) recomendado en pacientes pediátricos?
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Qual es el inicio y duración de diltiazem (Cardizem)?
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Quais son algunas consideraciones especiales para diltiazem (Cardizem)?
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Study Notes
Diltiazem (Cardizem) Overview
- Diltiazem class: Calcium channel blocker, used to manage cardiovascular conditions.
Mechanism of Action
- Blocks calcium ion influx into cardiac muscle, reducing contractility.
- Acts as both atrial and ventricular vasodilator.
- Increases preload and afterload, while decreasing myocardial oxygen demand.
Indications
- Primarily indicated for atrial fibrillation or flutter with rapid ventricular rates.
Contraindications
- Not recommended in patients with wide-complex tachycardia.
- Avoid in individuals with sick sinus syndrome.
- Contraindicated during cardiogenic shock.
Adverse Reactions
- Common side effects include flushing and headache.
- May cause bradycardia and hypotension in some patients.
Drug Interactions
- Careful use with digoxin, as it can increase the risk of toxicity.
- Interaction potential exists with beta blockers, requiring monitoring.
Dosage for Adults
- Initial IV dose: 0.25 mg/kg (average 20 mg) administered over two minutes.
- May repeat bolus after 15 minutes if needed.
- Alternative dosing of 0.35 mg/kg IV also available, given over two minutes.
Dosage for Pediatrics
- Diltiazem use in pediatric populations is not recommended.
Duration of Action
- Onset of action occurs within 2-5 minutes.
- Peak effects are variable, with overall duration lasting 1-3 hours.
Special Considerations
- Classified as pregnancy safety category C, indicating potential risks.
- Use cautiously in patients with pre-existing renal or hepatic dysfunction.
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Description
Este quiz aborda diltiazem (Cardizem), un medicamento utilizado como bloqueador de canales de calcio. Aspera tópicos como su mecanismo de acción, indicaciones y contraindicaciones, proporcionando un marco útil para estudiantes de farmacología.
