Digestive System Overview

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Questions and Answers

What are the three main food molecules in the typical American diet?

Carbohydrates, proteins, and fats

Where does the digestion of food begin?

Oral cavity

What is the role of saliva in the digestion of food?

Saliva contains digestive enzymes for carbohydrates and fats.

What happens to carbohydrates in the stomach?

<p>The digestion of carbohydrates stops when food enters the stomach.</p> Signup and view all the answers

Where does most digestion and absorption of nutrients occur?

<p>Small intestine</p> Signup and view all the answers

What kind of enzymes are most of the digestive enzymes of the small intestine?

<p>Proenzymes</p> Signup and view all the answers

What is the purpose of proenzymes being inactive?

<p>To prevent them from digesting the cells that produce them.</p> Signup and view all the answers

What is the name of the pancreatic proenzyme that is converted into trypsin?

<p>Trypsinogen</p> Signup and view all the answers

What type of enzyme is enteropeptidase?

<p>Brush-border enzyme</p> Signup and view all the answers

What is the name of the enzyme that resumes digestion of carbohydrates in the small intestine?

<p>Pancreatic amylase</p> Signup and view all the answers

What are the three brush-border digestive enzymes?

<p>Sucrase, maltase, and lactase</p> Signup and view all the answers

What are the three monosaccharides that result from carbohydrate digestion?

<p>Glucose, fructose, and galactose</p> Signup and view all the answers

Where are the monosaccharides absorbed into?

<p>The blood</p> Signup and view all the answers

What happens to proteins in the small intestine?

<p>They are broken down into single amino acids, di- and tripeptides</p> Signup and view all the answers

How are the monoglycerides and free fatty acids transported from the lumen of the small intestine?

<p>They diffuse across the cell membrane of the epithelial cells of the small intestine.</p> Signup and view all the answers

What is the name of the transport molecule that moves cholesterol from the lumen of the small intestine?

<p>A transport molecule</p> Signup and view all the answers

What are monoglycerides and free fatty acids assembled into inside the epithelial cells?

<p>Triglycerides</p> Signup and view all the answers

What is the name of the complex that is formed by the combination of triglycerides, cholesterol, and proteins in the small intestine?

<p>Chylomicrons</p> Signup and view all the answers

Where are chylomicrons exocytosed into?

<p>The interstitial fluid of the wall of the small intestine</p> Signup and view all the answers

What is the name of the lymph capillaries that chylomicrons enter?

<p>Lacteals</p> Signup and view all the answers

What is the fate of the absorbed nutrient molecules?

<p>It depends on the metabolic state of the body's cells.</p> Signup and view all the answers

Flashcards

Digestive System Function

Mechanically and enzymatically breaks down food, absorbs usable molecules.

Typical American Diet

Primarily carbohydrates, proteins, and fats.

Carbohydrates

Poly- and disaccharides.

Proteins

Chains of amino acids.

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Fats

Triglycerides, cholesterol, and long-chain fatty acids.

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Digestion (oral cavity)

Food is chewed, enzymes break down carbs and fats.

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Saliva

Contains enzymes for initial carbohydrate and fat digestion.

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Esophagus

Tube connecting mouth to stomach.

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Stomach

Protein digestion begins here; carbohydrate digestion stops.

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Small Intestine

Site of most digestion and absorption.

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Pancreatic Enzymes

Secreted by pancreas, most are proenzymes initially.

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Proenzymes

Inactive form of enzymes, prevent self-digestion.

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Trypsinogen

Pancreatic proenzyme, activated into trypsin.

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Enteropeptidase

Enzyme activates trypsin.

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Brush Border Enzymes

Enzymes on epithelial cell membrane of the small intestine.

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Pancreatic Amylase

Enzyme resuming carb digestion, acting in small intestine.

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Sucrase, Maltase, Lactase

Brush-border enzymes digesting disaccharides in small intestine.

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Monosaccharides

Glucose, fructose, and galactose, absorbed into blood.

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Amino Acids

Protein breakdown products, absorbed into blood.

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Chylomicrons

Fat droplets combined with protein for transport.

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Absorption

Taking in of digested nutrients.

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Study Notes

Digestive System Overview

  • Digestive system functions include mechanical/enzymatic breakdown of food, and absorption of molecules.
  • Main food molecules are carbohydrates (poly/disaccharides), proteins, and fats (triglycerides, cholesterol).
  • Digestion begins in the oral cavity with chewing and enzyme secretion in saliva (carb/fat enzymes).
  • Food is swallowed to the stomach where protein digestion starts, and initial fat digestion continues.
  • Stomach acid denatures carbohydrate enzymes, stopping carbohydrate digestion.
  • Most digestion/absorption occurs in the small intestine.
  • Many digestive enzymes are secreted as inactive proenzymes.
  • Pancreatic proenzyme (trypsinogen) is activated (to trypsin) by enteropeptidase in small intestine.
  • Enteropeptidase is attached to epithelial cell membranes (brush border enzymes).
  • Brush border enzymes (e.g., sucrase, maltase, lactase) digest disaccharides.
  • Monosaccharides (glucose, fructose, galactose) are absorbed into the bloodstream.
  • Proteins are broken down into amino acids, and di-tripeptides, absorbed into bloodstream.
  • Triglycerides/long chain fatty acids are broken down, absorbed, and reformed into chylomicrons.
  • Chylomicrons are absorbed into lymphatic system.
  • Cholesterol is transported in the small intestine by a transport molecule.

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