Digestive System Functions and Anatomy
24 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the name of the continuous coiled hollow tube that makes up the alimentary canal?

  • Nervous System
  • Gastrointestinal Tract (correct)
  • Circulatory System
  • Respiratory Tract
  • What are the four layers of tissue found in the alimentary canal organs, from deep to superficial?

  • Muscularis Externa, Submucosa, Serosa, Mucosa
  • Submucosa, Mucosa, Serosa, Muscularis Externa
  • Mucosa, Submucosa, Muscularis Externa, Serosa (correct)
  • Serosa, Muscularis Externa, Submucosa, Mucosa
  • What are the three structural modifications that increase the surface area of the small intestine?

    Microvilli, Villi, and Circular Folds

    Which of the following is NOT a function of the liver?

    <p>Digests fats using lipases (A)</p> Signup and view all the answers

    What is the name of the process that breaks down substances into simpler substances, releasing energy?

    <p>Catabolism</p> Signup and view all the answers

    What is the preferred source for cellular energy production by the body?

    <p>Carbohydrates</p> Signup and view all the answers

    What are the three phases of deglutition, or swallowing?

    <p>Buccal, Pharyngeal, Esophogeal (D)</p> Signup and view all the answers

    What are the four main categories of food that are broken down during chemical digestion? (Select all that apply)

    <p>Proteins (B), Nucleic Acids (C), Lipids (D), Carbohydrates (F)</p> Signup and view all the answers

    The large intestine plays a major role in the absorption of nutrients into the bloodstream.

    <p>False (B)</p> Signup and view all the answers

    What is the main digestive function of pancreatic enzymes?

    <p>Complete digestion of starch (A)</p> Signup and view all the answers

    Cholesterol is used to make ATP, which is the body's primary energy molecule.

    <p>False (B)</p> Signup and view all the answers

    Which of the following factors does NOT influence the body's basic metabolic rate (BMR)?

    <p>Food intake (D)</p> Signup and view all the answers

    What are the two main mechanisms that the body uses to regulate body temperature?

    <p>Heat-loss and heat-promotion (B)</p> Signup and view all the answers

    A ______ is a controlled hyperthermia that can result from infection, cancer, or allergic reactions.

    <p>fever</p> Signup and view all the answers

    What are the two types of proteins involved in the transport of cholesterol and fatty acids in the bloodstream?

    <p>Low-density lipoproteins (LDLs) and High-density lipoproteins (HDLs)</p> Signup and view all the answers

    What is the name of the metabolic process that builds larger molecules from smaller ones?

    <p>Anabolism (A)</p> Signup and view all the answers

    The body's thermostat is located in the ______.

    <p>hypothalamus</p> Signup and view all the answers

    What are the three metabolic pathways involved in cellular respiration?

    <p>Glycolysis, Krebs Cycle, and Electron Transport Chain</p> Signup and view all the answers

    What is the unit of measure for the energy value of foods and the amount of energy used by the body?

    <p>Kilocalorie (C)</p> Signup and view all the answers

    Match the following metabolic functions of the liver with their descriptions:

    <p>Glycogenesis = Glucose is converted to glycogen and stored in the liver Glycogenolysis = Glucose is released from the liver after conversion from glycogen Gluconeogenesis = Glucose is produced from fats and proteins</p> Signup and view all the answers

    The function of the rooting reflex is to help the infant find the nipple.

    <p>True (A)</p> Signup and view all the answers

    Appendicitis is a condition that affects the gastrointestinal tract, but does not specifically involve the appendix.

    <p>False (B)</p> Signup and view all the answers

    What is the primary function of the muscularis externa layer in the large intestine?

    <p>To produce teniae coli which causes the wall to pucker into haustra</p> Signup and view all the answers

    Which of the following is NOT a common digestive problem associated with middle age?

    <p>Appendicitis (B)</p> Signup and view all the answers

    Flashcards

    Ingestion

    The process of taking food into the mouth.

    Digestion

    The breakdown of food into smaller molecules, both physically and chemically.

    Absorption

    The movement of nutrients from the digestive system into the bloodstream.

    Defecation

    The elimination of indigestible waste from the body through the anus.

    Signup and view all the flashcards

    Alimentary Canal (GI tract)

    The continuous tube that runs from the mouth to the anus, responsible for digestion and waste elimination. Includes the mouth, pharynx, esophagus, stomach, small intestine, large intestine, and anus.

    Signup and view all the flashcards

    Accessory Digestive Organs

    Organs that aid in digestion but are not part of the alimentary canal. Examples include teeth, tongue, salivary glands, liver, gallbladder, and pancreas.

    Signup and view all the flashcards

    Lumen

    The space inside the alimentary canal where food travels through.

    Signup and view all the flashcards

    Mucosa

    The innermost layer of the alimentary canal, made of epithelial cells, connective tissue, and a smooth muscle layer.

    Signup and view all the flashcards

    Submucosa

    The layer of connective tissue just beneath the mucosa, containing blood vessels, nerves, and lymphatic tissue.

    Signup and view all the flashcards

    Muscularis Externa

    Outer layer of smooth muscle in the alimentary canal, composed of circular and longitudinal layers. Responsible for peristalsis.

    Signup and view all the flashcards

    Serosa

    The outermost layer of the alimentary canal, composed of fluid-producing cells. Includes the visceral peritoneum, which covers the organs, and the parietal peritoneum, which lines the abdominal cavity.

    Signup and view all the flashcards

    Peristalsis

    The wave-like contractions of smooth muscle that propels food through the alimentary canal.

    Signup and view all the flashcards

    Segmentation

    A type of propulsion in the small intestine where food is moved back and forth, aiding in mixing with digestive juices.

    Signup and view all the flashcards

    Pharynx

    The opening at the back of the mouth that connects to the esophagus and trachea.

    Signup and view all the flashcards

    Esophagus

    The muscular tube that connects the pharynx to the stomach, transporting food by peristalsis.

    Signup and view all the flashcards

    Cardioesophageal Sphincter

    A muscular ring that controls the opening between the esophagus and the stomach, preventing food from backing up into the esophagus.

    Signup and view all the flashcards

    Stomach

    The J-shaped organ located on the left side of the abdominal cavity, where food is temporarily stored and chemically broken down.

    Signup and view all the flashcards

    Pyloric Sphincter

    The muscular ring that controls the opening between the stomach and the small intestine, releasing chyme into the duodenum.

    Signup and view all the flashcards

    Chyme

    The processed food mixture that leaves the stomach and enters the small intestine.

    Signup and view all the flashcards

    Duodenum

    The first section of the small intestine, attached to the stomach. It receives chyme from the stomach and begins the digestion of fats and proteins.

    Signup and view all the flashcards

    Jejunum

    The middle section of the small intestine, responsible for absorbing nutrients.

    Signup and view all the flashcards

    Ileum

    The final section of the small intestine, connecting to the large intestine. It absorbs water, electrolytes, and remaining nutrients.

    Signup and view all the flashcards

    Microvilli

    Microscopic projections on the surface of the small intestine cells, increasing the surface area for nutrient absorption.

    Signup and view all the flashcards

    Villi

    Finger-like projections of the mucosa in the small intestine, increasing surface area for nutrient absorption.

    Signup and view all the flashcards

    Circular Folds (Plicae Circulares)

    Deep folds of mucosa and submucosa in the small intestine, increasing surface area for nutrient absorption.

    Signup and view all the flashcards

    Cecum

    The sac-like first part of the large intestine, where the appendix is attached.

    Signup and view all the flashcards

    Appendix

    A small, finger-like projection extending from the cecum, containing lymphatic tissue.

    Signup and view all the flashcards

    Colon

    The main part of the large intestine, responsible for water absorption and waste formation. Composed of the ascending, transverse, descending, and sigmoid colon.

    Signup and view all the flashcards

    Rectum

    The last section of the large intestine, located in the pelvis, where waste is stored before defecation.

    Signup and view all the flashcards

    Anal Canal

    The final canal of the digestive system, connecting the rectum to the anus. It contains internal and external sphincters that control defecation.

    Signup and view all the flashcards

    Anus

    The opening at the end of the digestive system, through which waste is eliminated.

    Signup and view all the flashcards

    Deglutition (Swallowing)

    The process of swallowing, involving the buccal and pharyngeal-esophageal phases.

    Signup and view all the flashcards

    Gastrin

    The hormone released from the stomach in response to food or rising pH, which stimulates the production of gastric juices.

    Signup and view all the flashcards

    Mechanical Digestion

    The process of breaking down food into smaller particles, primarily by chewing and churning.

    Signup and view all the flashcards

    Chemical Digestion

    The process of chemically breaking down food molecules into smaller units using enzymes.

    Signup and view all the flashcards

    Liver

    A major gland located on the right side of the abdomen, under the diaphragm. It produces bile, which aids in fat digestion.

    Signup and view all the flashcards

    Bile

    A fluid produced by the liver, which emulsifies fats, breaking them into smaller droplets for easier digestion.

    Signup and view all the flashcards

    Gallbladder

    A small sac located in the hollow fossa of the liver, where bile is stored and concentrated.

    Signup and view all the flashcards

    Pancreas

    A gland located posterior to the stomach, producing digestive enzymes and hormones such as insulin and glucagon.

    Signup and view all the flashcards

    Insulin

    A hormone produced by the pancreas that regulates blood glucose levels by lowering them.

    Signup and view all the flashcards

    Glucagon

    A hormone produced by the pancreas that regulates blood glucose levels by raising them.

    Signup and view all the flashcards

    Cellular Respiration

    The process by which cells convert glucose into energy (ATP). It involves glycolysis, the Krebs cycle, and the electron transport chain.

    Signup and view all the flashcards

    Glycolysis

    The initial stage of cellular respiration, occurring in the cytoplasm. Glucose is split into two pyruvic acid molecules, yielding a small amount of ATP.

    Signup and view all the flashcards

    Krebs Cycle

    A series of reactions occurring in the mitochondria, where pyruvic acid is further broken down to CO2, generating a small amount of ATP and electron carriers.

    Signup and view all the flashcards

    Electron Transport Chain

    A chain of protein carriers embedded in the mitochondrial membrane, where electrons from the Krebs cycle are used to generate ATP. It is the primary source of ATP production.

    Signup and view all the flashcards

    Study Notes

    Digestive System Functions

    • Ingestion—taking in food
    • Digestion—breaking food down physically and chemically
    • Absorption—movement of nutrients into the bloodstream
    • Defecation—rids the body of indigestible waste

    Organs of the Digestive System

    • Two main groups of organs:
      • Alimentary canal (gastrointestinal or GI tract)—continuous, coiled hollow tube. These organs ingest, digest, absorb, and defecate.
      • Accessory digestive organs—include teeth, tongue, and other digestive organs.

    Organs of the Alimentary Canal

    • Mouth
    • Pharynx
    • Esophagus
    • Stomach
    • Small intestine
    • Large intestine
    • Anus

    Mouth (Oral Cavity) Anatomy

    • Lips (labia)—protect the anterior opening
    • Cheeks—form the lateral walls
    • Hard palate—forms the anterior roof
    • Soft palate—forms the posterior roof
    • Uvula—fleshy projection of the soft palate
    • Vestibule—space between lips externally and teeth and gums internally
    • Oral cavity proper—area contained by the teeth
    • Tongue—attached at hyoid bone and styloid processes of skull; attached to floor of the mouth by lingual frenulum.
    • Tonsils (palatine and lingual)—located at posterior end and base of tongue respectively.

    Mouth Physiology

    • Mastication (chewing) of food
    • Mixing masticated food with saliva
    • Initiation of swallowing by the tongue
    • Allows for the sense of taste

    Pharynx Anatomy

    • Nasopharynx—not part of the digestive system
    • Oropharynx—posterior to oral cavity
    • Laryngopharynx—below the oropharynx and connected to the esophagus

    Pharynx Physiology

    • Serves as a passageway for air and food
    • Food is propelled to the esophagus by two muscle layers:
      • Longitudinal inner layer
      • Circular outer layer
    • Food movement is by alternating contractions of the muscle layers (peristalsis)

    Esophagus Anatomy and Physiology

    • Anatomy:
      • About 10 inches long
      • Runs from pharynx to stomach through the diaphragm
    • Physiology:
      • Conducts food by peristalsis (slow rhythmic squeezing)
      • Passageway for food only (respiratory system branches off after the pharynx)

    Layers of Tissue in the Alimentary Canal Organs

    • Four layers from deep to superficial:
      • Mucosa
      • Submucosa
      • Muscularis externa
      • Serosa

    Mucosa Layer

    • Innermost, moist membrane consisting of:
      • Surface epithelium
      • Small amount of connective tissue (lamina propria)
      • Small smooth muscle layer
    • Lines the cavity (known as the lumen)

    Submucosa Layer

    • Just beneath the mucosa
    • Soft connective tissue with blood vessels, nerve endings, mucosa-associated lymphoid tissue, and lymphatics

    Muscularis Externa Layer

    • Smooth muscle
      • Inner circular layer
      • Outer longitudinal layer
    • Serosa—outermost layer of the wall contains fluid-producing cells
    • Visceral peritoneum—outermost layer that is continuous with the innermost layer
    • Parietal peritoneum—innermost layer that lines the abdominopelvic cavity

    Alimentary Canal Nerve Plexuses

    • Two important nerve plexuses that serve the alimentary canal.
      • Submucosal nerve plexus
      • Myenteric nerve plexus
    • Function is to regulate mobility and secretory activity of GI tract organs.

    Stomach Anatomy

    • Location: Left side of abdominal cavity
    • Food enters at the cardioesophageal sphincter
    • Food empties into the small intestine at the pyloric sphincter (valve)
    • Regions of the stomach:
      • Cardiac region—near the heart
      • Fundus—expanded portion lateral to the cardiac region
      • Body—midportion
      • Pylorus—funnel-shaped terminal end
    • Rugae—internal folds of the mucosa
    • Stomach can stretch and hold 4 L (1 gallon) of food when full
    • External regions:
      • Lesser curvature—concave medial surface
      • Greater curvature—convex lateral surface

    Stomach Layers

    • Muscularis externa has a third layer (oblique)
    • Layers of peritoneum attached to the stomach:
      • Lesser omentum—attaches the liver to the lesser curvature
      • Greater omentum—attaches the greater curvature to the posterior body wall; embedded fat insulates, cushions, and protects abdominal organs

    Stomach Physiology

    • Temporary storage tank for food
    • Site of food breakdown
    • Chemical breakdown of protein begins
    • Delivers chyme (processed food) to the small intestine

    Structure of Stomach Mucosa

    • Mucosa is simple columnar epithelium
    • Mucous neck cells—produce a sticky alkaline mucus
    • Gastric glands—situated in gastric pits and secrete gastric juice
    • Chief cells—produce protein-digesting enzymes (pepsinogens)
    • Parietal cells—produce hydrochloric acid
    • Enteroendocrine cells—produce gastrin

    Small Intestine

    • The body's major digestive organ
    • Site of nutrient absorption into the blood
    • Muscular tube extending from the pyloric sphincter to the ileocecal valve
    • Suspended from the posterior abdominal wall by the mesentery

    Subdivisions of the Small Intestine

    • Duodenum —attached to the stomach; curves around the head of the pancreas
    • Jejunum—attaches anteriorly to the duodenum
    • Ileum—extends from jejunum to large intestine.

    Chemical Digestion in the Small Intestine

    • Chemical digestion begins in the small intestine
    • Enzymes are produced by:
      • Intestinal cells
      • Pancreas
    • Pancreatic ducts carry enzymes to the small intestine
    • Bile, formed by the liver, enters via the bile duct.

    Small Intestine Anatomy

    • Three structural modifications that increase surface area:
      • Microvilli—tiny projections of the plasma membrane
      • Villi—fingerlike structures formed by the mucosa
      • Circular folds (plicae circulares)—deep folds of mucosa and submucosa

    Large Intestine

    • Larger in diameter, but shorter in length, than the small intestine
    • Extends from the ileocecal valve to the anus
    • Subdivisions:
      • Cecum
      • Appendix
      • Colon
        • Ascending
        • Transverse
        • Descending
        • Sigmoid
      • Rectum
      • Anal canal

    Large Intestine Anatomy

    • Cecum—saclike first part of the large intestine; appendix hangs from the cecum
    • Appendix—accumulation of lymphatic tissue that sometimes becomes inflamed (appendicitis)
    • Colon (ascending, transverse, descending, sigmoid)—travels up right side of abdomen, across abdominal cavity, down left side, and into the pelvis.
    • Rectum—and anus also located in the pelvis
    • Anus—opening of the large intestine; has external and internal sphincters (normally closed except during defecation)

    Large Intestine Anatomy

    • No villi present
    • Goblet cells produce alkaline mucus which lubricates the passage of feces
    • Muscularis externa layer is reduced to three bands of muscle called teniae coli
    • These bands cause the wall to pucker into haustra (pocketlike sacs)

    Accessory Digestive Organs

    • Teeth
    • Salivary glands
    • Pancreas
    • Liver
    • Gallbladder

    Teeth

    • Function is to masticate (chew) food
    • Humans have two sets of teeth:
      • Deciduous ("milk") teeth—20 teeth by age two
      • Permanent teeth—32 teeth (some people don't have wisdom teeth); replace deciduous teeth between ages 6 and 12
    • Classification of Teeth:
      • Incisors-cutting
      • Canines (eyeteeth)—tearing or piercing
      • Premolars (bicuspids)—grinding
      • Molars—grinding

    Regions of a Tooth

    • Crown—exposed part
    • Enamel—hardest substance in the body
    • Dentin—found deep to the enamel and forms the bulk of the tooth
    • Pulp cavity—contains connective tissue, blood vessels, and nerve fibers.
    • Root canal—where the pulp cavity extends into the root.
    • Neck—region in contact with the gum
    • Cementum—covers outer surface of root; attaches tooth to periodontal membrane

    Salivary Glands

    • Three pairs of salivary glands empty secretions into the mouth:
      • Parotid glands—found anterior to the ears
        • Submandibular glands
        • Sublingual glands —both empty saliva into the floor of the mouth through small ducts

    Saliva

    • Mixture of mucus and serous fluids
    • Helps to form a food bolus
    • Contains salivary amylase to begin starch digestion
    • Dissolves chemicals so they can be tasted.

    Pancreas

    • Found posterior to the parietal peritoneum (retroperitoneal)
    • Extends across the abdomen from spleen to duodenum
    • Produces digestive enzymes that break down all categories of food.
    • Enzymes enter the duodenum
    • Alkaline fluid introduced with enzymes neutralizes acidic chyme coming from the stomach; hormones produced by the pancreas (insulin, glucagon).

    Liver

    • Largest gland in the body; located on the right side of the body under the diaphragm.
    • Consists of four lobes
    • Suspended from the diaphragm and abdominal wall by the falciform ligament
    • Connected to the gallbladder via the common hepatic duct

    Bile

    • Produced by cells in the liver
    • Leaves the liver through the common hepatic duct
    • Composition:
      • Bile salts
      • Bile pigments (mostly bilirubin from the breakdown of hemoglobin)
      • Cholesterol
      • Phospholipids
      • Electrolytes
    • Function: Emulsify fats; physically break large fat globules into smaller ones.

    Gallbladder

    • Sac found in a hollow fossa of the liver
    • When no digestion is occurring, bile backs up the cystic duct for storage in the gallbladder
    • When digestion of fatty food is occurring, bile is introduced into the duodenum from the gallbladder.
    • Gallstones are crystallized cholesterol which can cause blockages.

    Functions of the Digestive System

    • Ingestion—placing food into the mouth
    • Propulsion—moving foods from one region of the digestive system to another
    • Peristalsis—alternating waves of contraction and relaxation that squeezes food along the GI tract
    • Segmentation—moving materials back and forth to aid with mixing in the small intestine.

    Digestion in the Small Intestine

    • Enzymes from the brush border function to:
      • Break double sugars into simple sugars
      • Complete some protein digestion
    • Pancreatic enzymes play the major digestive function:
      • Help complete digestion of starch (pancreatic amylase)
      • Carry out about half of all digestion of protein
      • Digest fats using lipases from the pancreas
      • Digest nucleic acids using nucleases
      • Alkaline content neutralizes acidic chyme.

    Regulation of Pancreatic Juice Secretion

    • Release of pancreatic juice into the duodenum is stimulated by:
      • Vagus nerve
      • Local hormones
        • Secretin
        • Cholecystokinin (CCK)
    • Hormones travel the blood to stimulate the pancreas to release enzyme- and bicarbonate-rich product.
    • Secretin causes the liver to increase bile output.
    • CCK causes the gallbladder to release stored bile.
    • Bile is necessary for fat absorption and absorption of fat-soluble vitamins (K, D, A).

    Absorption in the Small Intestine

    • Water is absorbed along the length of the small intestine
    • End products of digestion:
      • Most substances are absorbed by active transport through cell membranes
      • Lipids are absorbed by diffusion
    • Substances are transported to the liver by the hepatic portal vein or lymph

    Propulsion in the Small Intestine

    • Peristalsis is the major means of moving food
    • Segmental movements
      • Mix chyme with digestive juices
      • Aid in propelling food

    Food Breakdown and Absorption in the Large Intestine

    • No digestive enzymes are produced
    • Resident bacteria digest remaining nutrients
    • Produce some vitamin K and B
    • Release gases
    • Water and vitamins K and B are absorbed
    • Remaining materials are eliminated via feces
    • Feces contains:
      • Undigested food residues
      • Mucus
      • Bacteria
      • Water

    Propulsion in the Large Intestine

    • Sluggish peristalsis
    • Mass movements
      • Slow, powerful movements
      • Occur three to four times per day
    • Presence of feces in the rectum causes a defecation reflex
    • Internal anal sphincter is relaxed
    • Defecation occurs with relaxation of the voluntary (external) anal sphincter

    Nutrition

    • Nutrient-substance used by the body for growth, maintenance, and repair
    • Major nutrients:
      • Carbohydrates
      • Lipids
      • Proteins
      • Water
    • Minor nutrients:
      • Vitamins
      • Minerals

    Dietary Sources of Major Nutrients

    • Carbohydrates (mostly from plants; exceptions: lactose from milk and small amounts of glycogen from meats)
    • Lipids (saturated fats from animal products; unsaturated fats from nuts, seeds, and vegetable oils; cholesterol from egg yolk, meats, and milk)
    • Proteins (complete proteins from animal products, essential amino acids that our bodies cannot make must be consumed via our diet. Legumes and beans are incomplete proteins)
    • Vitamins (used as coenzymes, found in all major food groups)
    • Minerals (play many roles in the body, found in vegetables, legumes, milk, and some meats).

    Metabolism

    • Chemical reactions necessary to maintain life
    • Catabolism—substances are broken down; energy released
    • Anabolism—larger molecules are built from smaller ones.

    Carbohydrate Metabolism

    • Carbohydrates are the body's preferred source to produce cellular energy (ATP)
    • Glucose (blood sugar)
      • Major breakdown product of carbohydrate digestion
      • Fuel used to make ATP

    Cellular Respiration

    • Oxygen-using events within the cells to create ATP from ADP.
    • Carbon leaves cells as carbon dioxide (CO2)
    • Hydrogen atoms combine with oxygen to form water
    • Energy produced adds a phosphorus to ADP to produce ATP
    • ATP can be broken down to release energy for cellular use

    Metabolic Pathways Involved in Cellular Respiration

    • Glycolysis—energizes a glucose molecule so it can be split into two pyruvic acid molecules and yield ATP.
    • Krebs cycle—produces virtually all the carbon dioxide and water resulting from cell respiration, yields small amounts of ATP
    • Electron transport chain—hydrogen atoms removed during glycolysis and the Krebs cycle are delivered to protein carriers; hydrogen is split into hydrogen ions and electrons in the mitochondria; electrons give off energy in steps to enable the production of ATP

    Metabolism of Carbohydrates

    • Hyperglycemia—excessively high levels of glucose in the blood; Excess glucose stored in body cells as glycogen; if blood glucose levels are too high, excesses are converted to fat.
    • Hypoglycemia—low levels of glucose in the blood; Liver breaks down stored glycogen and releases glucose into the blood

    Fat Metabolism

    • Handled mostly by the liver
    • Use some fats to make ATP
    • Synthesizes lipoproteins, thromboplastin, and cholesterol
    • Releases breakdown products into the blood
    • Body cells remove fat (and cholesterol) to build membranes and steroid hormones.
    • Fats must first be broken down to acetic acid, in mitochondria, acetic acid is completely oxidized, producing water, carbon dioxide, and ATP
    • Acidosis (ketoacidosis) results from incomplete fat oxidation in which acetoacetic acid and acetone accumulate in the blood; breath has a fruity odor. common with "no carbohydrate" diets, uncontrolled diabetes mellitus, starvation.

    Protein Metabolism

    • Proteins are conserved by body cells (they are used for most cellular structures)
    • Ingested proteins are broken down to amino acids
    • Cells remove amino acids to build proteins
    • Synthesized proteins are actively transported across cell membranes
    • Amino acids are used to make ATP only when proteins are overabundant or there is a shortage of other sources.
    • Amine groups are removed from proteins as ammonia, the rest of the protein molecule enters the Krebs cycle in mitochondria; the liver converts harmful ammonia to urea.

    Role of the Liver in Metabolism

    • Several roles in digestion, manufactures bile, detoxifies drugs and alcohol, degrades hormones, produces cholesterol, blood proteins (albumin and clotting proteins), plays a central role in metabolism, can regenerate.

    Metabolic Functions of the Liver

    • Glycogenesis—"glycogen formation"; glucose molecules are converted to glycogen, stored in the liver.
    • Glycogenolysis—"glucose splitting"; glucose is released from the liver after conversion from glycogen.
    • Gluconeogenesis—"formation of new sugar"; glucose is produced from fats and proteins.
    • Fats and fatty acids absorbed by the liver; some are oxidized for liver energy production. Rest are broken down into simpler compounds and released into bloodstream.

    Cholesterol Metabolism and Transport

    • Cholesterol is not used to make ATP; Functions of cholesterol:
      • Serves as a structural basis of steroid hormones and vitamin D
      • Is a major building block of plasma membranes
    • Most cholesterol is produced in the liver (85 percent)
    • Cholesterol and fatty acids cannot freely circulate in the bloodstream; transported by lipoproteins (lipid-protein complexes). -Low-density lipoproteins (LDLs) transport to body cells; rated "bad lipoproteins" since they can lead to artherosclerosis
      • High-density lipoproteins (HDLs) transport from body cells to the liver

    Body Energy Balance

    • Energy intake = total energy output (heat + work + energy storage)
    • Energy intake is the energy liberated during food oxidation
    • Energy produced during glycolysis, Krebs cycle, and the electron transport chain
    • Energy output: energy lost as heat (60 percent) and energy stored as fat or glycogen.

    Regulation of Food Intake

    • Body weight is usually relatively stable
    • Energy intake and output remain about equal
    • Mechanisms that may regulate food intake: levels of nutrients in the blood, hormones, body temperature, psychological factors.

    Metabolic Rate and Body Heat Production

    • Basic metabolic rate (BMR)—amount of heat produced by the body per unit of time at rest.
    • Average BMR is about 60 to 72 kcal/hour
    • Kilocalorie (kcal) is the unit of measure for the energy value of foods and the amount of energy used by the body
    • Factors that influence BMR: surface area, gender, age, amount of thyroxine produced. More thyroxine means a higher metabolic rate.
    • Total metabolic rate (TMR) = Total amount of kilocalories the body must consume to fuel ongoing activities; TMR increases with an increase in body activity; TMR must equal consumed calories to maintain weight homeostasis and a constant weight.

    Body Temperature Regulation

    • Most energy is released as foods are oxidized, most energy escapes as heat.
    • The body has a narrow range of homeostatic temperature, must remain between 35.6°C and 37.8°C (96°F to 100°F)
    • The body's thermostat is in the hypothalamus
    • Initiates heat-loss or heat-promoting mechanisms
    • Heat-promoting mechanisms:
      • Vasoconstriction of blood vessels
      • Blood rerouted to deeper, more vital body organs
      • Shivering (contraction of muscles produces heat)
    • Heat-loss mechanisms:
      • Heat loss from the skin via radiation and evaporation
      • Skin blood vessels and capillaries are flushed with warm blood
      • Evaporation of perspiration cools the skin
    • Fever—controlled hyperthermia (results from infection, cancer, allergic reactions, CNS injuries); if the body thermostat is set too high, body proteins may be denatured and permanent brain damage may occur.

    Developmental Aspects of the Digestive System

    • The alimentary canal is a continuous tube by the fifth week of development
    • Digestive glands bud from the mucosa of the alimentary tube
    • The developing fetus receives all nutrients through the placenta
    • In newborns, feeding must be frequent, peristalsis is inefficient, and vomiting is common
    • Newborn reflexes:
      • Rooting reflex (helps infant find the nipple)
      • Sucking reflex (helps infant hold on to the nipple and swallow)
    • Teething begins around age six months
    • Problems of the digestive system:
      • Gastroenteritis (inflammation of the gastrointestinal tract)
      • Appendicitis (inflammation of the appendix)
      • Metabolism decreases with old age
      • Middle-age digestive problems
      • Ulcers
      • Gallbladder problems
    • Activity of digestive tract in old age: fewer digestive juices, peristalsis slows, diverticulosis and cancer are more common.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    Digestive System Lecture PDF

    Description

    This quiz covers the essential functions of the digestive system, including ingestion, digestion, absorption, and defecation. It also explores the various organs involved, particularly focusing on the anatomy of the alimentary canal and accessory digestive organs. Test your knowledge about how our digestive system processes food and nutrients.

    More Like This

    Use Quizgecko on...
    Browser
    Browser