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Questions and Answers
What is the primary function of bile salts?
What is the primary function of bile salts?
Which of the following is a consequence of impaired bilirubin uptake and conjugation by the liver?
Which of the following is a consequence of impaired bilirubin uptake and conjugation by the liver?
Where are plasma proteins, such as fibrinogen and thrombin, synthesized?
Where are plasma proteins, such as fibrinogen and thrombin, synthesized?
What is the role of IgA in the immune system?
What is the role of IgA in the immune system?
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How does bile duct occlusion impact IgA levels in the blood?
How does bile duct occlusion impact IgA levels in the blood?
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What is the primary function of Kupffer cells?
What is the primary function of Kupffer cells?
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Which of the following is NOT a characteristic of bilirubin?
Which of the following is NOT a characteristic of bilirubin?
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Which of the following is NOT a consequence of a lack of bile secretion?
Which of the following is NOT a consequence of a lack of bile secretion?
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What is the role of the rough endoplasmic reticulum (rER) in the synthesis of plasma proteins?
What is the role of the rough endoplasmic reticulum (rER) in the synthesis of plasma proteins?
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Which of the following arteries does not supply blood to the pancreas?
Which of the following arteries does not supply blood to the pancreas?
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What is the primary function of the fenestrated capillaries in the islets of Langerhans?
What is the primary function of the fenestrated capillaries in the islets of Langerhans?
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Which of the following enzymes is responsible for hydrolyzing triglycerides into fatty acids and monoglycerides?
Which of the following enzymes is responsible for hydrolyzing triglycerides into fatty acids and monoglycerides?
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Which of these components are part of the biliary tree?
Which of these components are part of the biliary tree?
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Which of the following nerve supplies the pancreas?
Which of the following nerve supplies the pancreas?
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Which of the following is NOT a function of the gallbladder?
Which of the following is NOT a function of the gallbladder?
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What is the primary reason for the inactive form of pancreatic enzymes being produced?
What is the primary reason for the inactive form of pancreatic enzymes being produced?
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What is the Glisson's capsule made of?
What is the Glisson's capsule made of?
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Why are the blood vessels of the Glisson's capsule located on its underside?
Why are the blood vessels of the Glisson's capsule located on its underside?
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What does the term "proenzyme" refer to in the context of pancreatic enzymes?
What does the term "proenzyme" refer to in the context of pancreatic enzymes?
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Which of the following is not a type of cell found in the islets of Langerhans?
Which of the following is not a type of cell found in the islets of Langerhans?
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What is the common bile duct formed by?
What is the common bile duct formed by?
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What is the primary function of the pancreatic-duodenal branches of the hepatic arteries?
What is the primary function of the pancreatic-duodenal branches of the hepatic arteries?
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What does the presence of an easily palpable liver edge indicate?
What does the presence of an easily palpable liver edge indicate?
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Which of the following correctly describes the capillary network in the exocrine pancreas?
Which of the following correctly describes the capillary network in the exocrine pancreas?
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What is the primary function of the Sphincter of Oddi?
What is the primary function of the Sphincter of Oddi?
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Which of the following is not a pancreatic enzyme that helps in the digestion of proteins?
Which of the following is not a pancreatic enzyme that helps in the digestion of proteins?
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What is the primary function of centro-acinar cells?
What is the primary function of centro-acinar cells?
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What distinguishes the lining epithelium of the duct system from the lining epithelium of the acini?
What distinguishes the lining epithelium of the duct system from the lining epithelium of the acini?
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How does the arrangement of the intercalated ducts differ from the intralobular ducts?
How does the arrangement of the intercalated ducts differ from the intralobular ducts?
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What is the primary function of the Interlobular Ducts?
What is the primary function of the Interlobular Ducts?
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What is the relationship between the Vagus nerve and pancreatic secretion?
What is the relationship between the Vagus nerve and pancreatic secretion?
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What is the significance of bicarbonate ions in the pancreatic secretion?
What is the significance of bicarbonate ions in the pancreatic secretion?
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Which of the following structures is NOT directly involved in the production of pancreatic juice?
Which of the following structures is NOT directly involved in the production of pancreatic juice?
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What is the primary role of the lining epithelium of the intercalated ducts?
What is the primary role of the lining epithelium of the intercalated ducts?
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What distinguishes the Interlobular Ducts from the Intralobular Ducts?
What distinguishes the Interlobular Ducts from the Intralobular Ducts?
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How does the pancreas's location contribute to its function?
How does the pancreas's location contribute to its function?
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Which of the following is NOT a characteristic of the process of insulin secretion?
Which of the following is NOT a characteristic of the process of insulin secretion?
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What is the role of glucokinase in the liver in response to insulin?
What is the role of glucokinase in the liver in response to insulin?
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Which of the following describes the fate of insulin-containing vesicles after their release?
Which of the following describes the fate of insulin-containing vesicles after their release?
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What is the primary function of somatostatin in regulating blood glucose levels?
What is the primary function of somatostatin in regulating blood glucose levels?
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What is the primary role of glucagon in maintaining blood glucose levels?
What is the primary role of glucagon in maintaining blood glucose levels?
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Flashcards
Muscularis Externa
Muscularis Externa
A layer of muscle in the gastrointestinal tract responsible for peristalsis.
Hepatocytes
Hepatocytes
Liver cells that perform metabolic, secretory, and endocrine functions.
Cystic Duct
Cystic Duct
Duct that connects the gallbladder to the common bile duct.
Sphincter of Oddi
Sphincter of Oddi
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Glisson's Capsule
Glisson's Capsule
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Liver Regeneration
Liver Regeneration
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Biliary Tree
Biliary Tree
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Exocytosis
Exocytosis
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Glucagon
Glucagon
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Somatostatin
Somatostatin
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Granulolysis
Granulolysis
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Glycogen
Glycogen
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Plasma Proteins Synthesis
Plasma Proteins Synthesis
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Emulsifying Action of Bile Salts
Emulsifying Action of Bile Salts
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Steatorrhea
Steatorrhea
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Bilirubin
Bilirubin
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Kupffer Cells
Kupffer Cells
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Jaundice
Jaundice
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Secretory IgA
Secretory IgA
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Conjugation of Bilirubin
Conjugation of Bilirubin
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Endocytosis of Hormones
Endocytosis of Hormones
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Translation
Translation
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Trypsinogen
Trypsinogen
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Chymotrypsinogen
Chymotrypsinogen
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Procarboxypeptidase
Procarboxypeptidase
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Lymph Capillaries
Lymph Capillaries
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Vagus Nerves
Vagus Nerves
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Pancreatic-duodenal Branches
Pancreatic-duodenal Branches
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Enzymes Activation
Enzymes Activation
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Amylase
Amylase
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Islet of Langerhans
Islet of Langerhans
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Exocrine pancreas
Exocrine pancreas
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Centro-acinar cells
Centro-acinar cells
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Intercalated ducts
Intercalated ducts
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Intralobular ducts
Intralobular ducts
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Interlobular ducts
Interlobular ducts
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Bicarbonate ions
Bicarbonate ions
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Digestive enzymes
Digestive enzymes
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Pancreatic duct system
Pancreatic duct system
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Hormonal regulation
Hormonal regulation
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Study Notes
Overview
- The liver, gallbladder, and pancreas are accessory digestive organs located outside of the digestive tube.
- The common bile duct from the liver and the main pancreatic duct from the pancreas join to form a single duct.
- The gallbladder joins the common bile duct via the cystic duct.
Liver
- Functions:
- Metabolic factory: synthesizes and breaks down various substances
- Site of glycogenesis, glycogenolysis, and synthesis of other proteins.
- Detoxification of many drugs and other poisons.
- Major aspects:
- Blood supply: hepatic portal vein (75%) and hepatic artery (25%)
- Formation and secretion of bile
- Storage of glycogen, triglycerides, and cholesterol
- Synthesis of urea and proteins
- Metabolism of cholesterol and fat
- Detoxification of many drugs and poisons
- Cleans bacteria from the blood
- Cellular components:
- Hepatocytes (80% of liver mass): polygonal cells joined in anastomosing plates, involved in metabolic activities.
- Kupffer cells: macrophages in sinusoids, responsible for engulfing bacteria.
- Fat-forming cells/Ito cells/stellate cells
Pancreas
- The pancreas is a lobulated structure.
- Two portions:
- Exocrine portion: produces pancreatic juice (~1.2L daily) essential for fat, CHO, and protein digestion.
- Acinar tissue: makes up most of the exocrine portion; contains pyramidal cells containing zymogen granules (inactive enzymes).
- Duct system: tubules (intercalated, intralobular, and interlobular ducts) transporting secretions.
- Endocrine portion: produces hormones regulating CHO metabolism (eg. insulin, glucagon); consists of islets of Langerhans.
- Exocrine portion: produces pancreatic juice (~1.2L daily) essential for fat, CHO, and protein digestion.
Gallbladder
- Pear-shaped organ storing and concentrating bile.
- Wall layers: mucosa (simple columnar epithelium), lamina propria (loose connective tissue), muscularis externa (smooth muscle), serosa (connective tissue).
- Contains Rokitansky-Aschoff sinuses in the mucosa.
- Luschka ducts are peculiar duct-like structures found on the hepatic surface, near the neck of the gallbladder.
Biliary Tree
- Composed of:
- Right hepatic duct
- Left hepatic duct
- Common hepatic duct
- Cystic duct
- Common bile duct
- Pancreatic duct
- Sphincter of Oddi
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Description
This quiz covers the roles and functions of the liver, gallbladder, and pancreas as accessory digestive organs. You'll learn about their anatomical connections, metabolic functions, and key cellular components. Test your knowledge on these vital organs that contribute significantly to the digestive process.