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Lecture 9.1b - Ischemic heart disease - diagnosis and management principles

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Lecture 9.1b - Ischemic heart disease - diagnosis and management principles

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Questions and Answers

What is the primary purpose of measuring the timing of biomarker release in diagnosing myocardial infarction?

To detect re-infarction and determine the effectiveness of treatment (correct)

To differentiate between acute and chronic infarction

To identify the location of the occluded artery

To determine the severity of the infarction

What is the primary goal of revascularisation in the management of myocardial infarction?

To restore blood flow to the affected area within 90 minutes of first medical contact (correct)

To prevent re-infarction and reduce the risk of complications

To reduce the severity of ischemic symptoms

To improve cardiac function and reduce morbidity

Which of the following biomarkers normalizes quickest after a myocardial infarction?

CK-MB (correct)

Troponin I

Myoglobins

Troponin T

What is the primary advantage of percutaneous coronary intervention (PCI) over fibrinolytic therapy in the management of myocardial infarction?

<p>PCI is more effective in opening up blocked arteries and restoring blood flow</p> Signup and view all the answers

What is the primary purpose of an electrocardiogram (ECG) in the diagnosis of myocardial infarction?

<p>To predict the distribution of ST-elevation relative to the occluded artery</p> Signup and view all the answers

Study Notes

Diagnosis

ECG is used in diagnosis
Biomarkers such as Myoglobins, Troponin I, T, CK-MB are used in diagnosis, which leak out of cells during an MI
Echocardiogram is used to detect wall motion abnormalities
Cardiac catheterisation is used in diagnosis

Biomarkers

Important to understand the timing of biomarker release
CK-MB normalises quicker and can be used to determine re-infarction
Biomarkers are released in a specific order after an MI, understanding this order is crucial

ECG

Predicted distribution of ST-elevation relative to occluded artery is important in diagnosis

Diagnostic Approach

No specific diagnostic approach is mentioned, but a combination of the above methods is likely used

Management Principles

All patients should receive anti-ischemic and analgesic medications early in care
Revascularisation should occur within 90 minutes of first medical contact
Percutaneous coronary intervention (PCI)/coronary angioplasty is the preferred revascularisation method
Fibronlytic therapy should be used if PCI cannot be performed

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Description

Learn about the diagnosis of myocardial infarction, including the use of ECG, biomarkers, echocardiogram, and cardiac catheterisation. Understand the role of biomarkers and their timing in diagnosis.