Diabetic Neuropathy and Peripheral Neuropathy in Diabetes

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18 Questions

Which condition in diabetic patients contributes to visual impairment?

Glaucoma

What is the common pattern of polyneuropathy seen in diabetic patients affecting both motor and sensory function?

Distal symmetric polyneuropathy

What may be the first event in a long series of complications ultimately leading to death in an individual with diabetic neuropathy?

Gangrene

Which of the following is commonly affected in diabetic patients by autonomic neuropathy?

Bladder function

What contributes to enhanced susceptibility to infections in diabetic patients?

Impaired cytokine production by macrophages

Which complication of diabetes can result in damage to the central nervous system?

Diabetic neuropathy

Which of the following is responsible for much of the morbidity and mortality in diabetes?

Long-term effects

What is one of the most common causes of mortality in long-standing diabetes?

Myocardial infarction

How long after the onset of hyperglycemia do chronic complications typically appear in diabetes?

15-20 years

What is the most common cause of mortality in long-standing diabetes according to the text?

Myocardial infarction

In which type of diabetes are the long-term effects, rather than acute metabolic complications, responsible for much of the morbidity and mortality?

Type 2 diabetes

What factor is shown to attenuate end-organ damage in prospective studies related to diabetes complications?

Effective glycemic control

What is the earliest manifestation of diabetic nephropathy?

Microalbuminuria

Which ethnic groups have a greater risk of developing end-stage renal disease due to diabetes?

Hispanics and African Americans

What is the leading cause of adult blindness in the United States?

Diabetic retinopathy

What lesion of retinopathy is induced by hypoxia and VEGF expression in the retina?

Neovascularization

Approximately what percentage of patients with diabetes develop some form of diabetic retinopathy 15 to 20 years after diagnosis?

70% to 90%

What is the current treatment for diabetic retinopathy?

Antiangiogenic agents blocking VEGF action

Explore the prevalence and clinical manifestations of peripheral neuropathy in individuals with diabetes, with a focus on distinguishing features between Type 1 and Type 2 diabetes. This quiz delves into Chapter 27's discussion on diabetic neuropathy and chronic diabetes.

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