12 Questions
What is the main cause of type 1 diabetes mellitus?
Absolute deficit in insulin secretion
Which of the following acute complications of diabetes is life-threatening and occurs without ketoacidosis?
Hyperosmolar coma
What distinguishes type 2 diabetes mellitus from type 1 diabetes mellitus?
Insulin resistance
Which organ is particularly affected by chronic hyperglycaemia in diabetes mellitus?
Kidneys
What are common symptoms associated with severe hyperglycaemia in diabetes?
Reduced visual acuity
According to the modern classification of diabetes mellitus by WHO, which group includes gestational diabetes mellitus?
Other specific forms of diabetes mellitus
What is the main link in the pathogenesis of type 1 DM?
Inflammation in the islets of Langerhans
How are B-cells predominantly destroyed in type 1 DM?
Apoptosis
Which of the following genetic combinations is associated with a high risk of developing type 1 DM?
DR3 and DR4 genes
Which cells show a genetically determined imbalance in type 1 DM?
Immune cells
What autoimmune disease is NOT mentioned as being associated with type 1 DM in the text?
Psoriasis
What role do HLA genes have in identifying possible genetic markers for type 1 DM?
They determine potential risk
Learn about the characteristics and complications of diabetes mellitus, a group of metabolic diseases characterized by high blood sugar levels. Understand how chronic hyperglycemia can affect various organs and lead to symptoms like polyuria, polydipsia, weight changes, and reduced visual acuity.
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