30 Questions
What type of healing must occur when an abscess is not able to evacuate the inciting agent completely?
Healing by second intention
What is a classic example of an ulcer according to the text?
Peptic ulcers in stomach and duodenum
What is a common predisposition for chronic suppurative inflammation as mentioned in the text?
Defective leukocyte function
What is dependent on the number of circulating neutrophils, normal chemotaxis, and adhesion at the site of tissue injury?
Accumulation of polymorphs
Which disease is NOT listed as an inherited deficiency in the inflammatory response?
Radiation therapy-induced deficiency
What process is essential for the removal of exogenous material according to the text?
Phagocytosis and killing/degradation
What is the outcome of acute inflammation as mentioned in the text?
Resolution
Which molecule plays a predominant role in the firm adhesion step of leukocyte migration?
Integrins
What cell types are characteristic of chronic inflammation?
Round cells like macrophages, lymphocytes, and plasma cells
Which of the following is NOT a step in the multistep process of leukocyte migration through blood vessels?
Migration away from chemoattractants
What is the characteristic feature of chronic inflammation compared to acute inflammation?
Macrophages predominance
How does chronic inflammation usually arise according to the text?
Primarily, de novo
What are the two mechanisms that can lead to granulomatous inflammation?
Infectious agents and foreign bodies
Which of the following is NOT an example of granulomatous inflammation mentioned in the text?
Malaria
What type of hypersensitivity reaction can lead to granulomatous inflammation?
Type 4 hypersensitivity
What do epithelioid cells do in the context of granulomatous inflammation?
Surround particles like bacteria
Which type of cells are known as multinucleated histiocytic giant cells?
Langhan's cells
What is the role of activated T cells in granulomatous inflammation?
Produce cytokines
What type of cellular infiltrate is predominantly seen in primary chronic inflammation?
Chronic inflammatory cells
Which of the following infections are examples of agents that can resist phagocytosis or intracellular killing?
Tuberculosis, Leprosy, Syphilis
What characterizes conditions where mononuclear phagocytes dominate the histological picture?
Mononuclear phagocytes
Which of the following materials may cause foreign body reactions in chronic inflammation?
Bone, Uric acid crystals, Cholesterol crystals
What is the main mechanism responsible for macrophage accumulation in tissues (initially monocytes)?
Continued recruitment from the microcirculation
Which type of inflammation is characterized by the formation of granulomas?
Chronic granulomatous inflammation
What type of necrosis is commonly seen in granulomas of tuberculosis?
Caseous necrosis
What is the characteristic feature of a typical tuberculous granuloma?
Central necrosis
What type of cells are responsible for the formation of asteroid bodies in silicosis?
Giant cells
Which inflammatory cells are primarily involved in chronic inflammation in the lung?
Macrophages
What type of granuloma reaction is commonly associated with Crohn’s Disease?
Foreign body granuloma
What pathogen is responsible for Fish Tank Granuloma?
Mycobacterium marinum
Test your knowledge on the relationship between diabetes mellitus and inflammation. Explore the types of chronic inflammation associated with diabetes, including defects in phagocytosis and primary chronic inflammation.
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