Diabetes Medications: Non-Insulin Injectable Agents

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Questions and Answers

What is the effect of decreasing caloric intake and increasing physical activity on insulin needs?

  • Insulin needs are decreased (correct)
  • Insulin needs remain the same
  • Insulin therapy is no longer necessary
  • Insulin needs are increased

What is the primary mechanism of action of biguanides such as metformin?

  • Stimulating insulin release
  • Increasing insulin resistance
  • Delaying carbohydrate absorption
  • Reducing glucose production in the liver and increasing insulin sensitivity (correct)

Which oral antidiabetic medication is also chemically related to sulfonamide antibacterial medications?

  • Metformin
  • Acarbose
  • Rosiglitazone
  • Glyburide (correct)

What is a common side effect of thiazolidinediones such as rosiglitazone?

<p>Upper respiratory tract infections (D)</p> Signup and view all the answers

Which oral antidiabetic medication acts on the intestine to delay carbohydrate absorption?

<p>Acarbose (B)</p> Signup and view all the answers

What is a unique feature of meglitinides such as repaglinide compared to sulfonylureas?

<p>They are shorter-acting (B)</p> Signup and view all the answers

What is the primary mechanism of action of sitagliptin in the management of diabetes?

<p>Inhibiting the inactivation of the hormone that stimulates insulin release (A)</p> Signup and view all the answers

Which of the following medications is used as an adjunctive therapy to regulate glucose postprandial in type 1 and type 2 diabetes?

<p>Pramlintide (A)</p> Signup and view all the answers

Which of the following signs or symptoms is NOT associated with hypothyroidism?

<p>Increased heart rate (B)</p> Signup and view all the answers

What is the primary indication for the use of propylthiouracil?

<p>Hyperthyroidism (C)</p> Signup and view all the answers

What is the primary mechanism of action of exenatide in the management of type 2 diabetes?

<p>Mimicking the action of incretin hormones (A)</p> Signup and view all the answers

Which of the following laboratory tests is elevated in hypothyroidism?

<p>TSH (D)</p> Signup and view all the answers

What is the primary reason for 'tight control' being more important in Type 1 diabetes compared to Type 2 diabetes?

<p>Microvascular complications are more prevalent in Type 1 diabetes (B)</p> Signup and view all the answers

Which of the following insulin types does not have a peak action?

<p>Long duration insulin (D)</p> Signup and view all the answers

What is the primary factor that influences the dosage schedule of insulin therapy?

<p>Blood sugar levels (C)</p> Signup and view all the answers

What is the advantage of using premixed vials in insulin therapy?

<p>They are more convenient for common combinations (A)</p> Signup and view all the answers

Which of the following is NOT a factor that increases insulin needs?

<p>Thyroid hormone replacement (C)</p> Signup and view all the answers

What is the recommended method of administration for insulin therapy?

<p>Subcutaneous injection (D)</p> Signup and view all the answers

What is the primary advantage of using gliptins in diabetes management?

<p>Reduced risk of hypoglycemia (A)</p> Signup and view all the answers

What is the mechanism of action of amylin analogs in diabetes management?

<p>Regulating glucose postprandial (D)</p> Signup and view all the answers

What is the primary indication for the use of levothyroxine in thyroid disorders?

<p>Hypothyroidism (C)</p> Signup and view all the answers

What is the effect of incretin mimetics on the pancreas in diabetes management?

<p>Stimulate insulin release based on food intake (A)</p> Signup and view all the answers

Which oral antidiabetic medication is used to stimulate the pancreas to secrete insulin based on food intake?

<p>Exenatide (D)</p> Signup and view all the answers

What is the primary side effect of gliptins in diabetes management?

<p>Runny nose, sore throat, and headache (A)</p> Signup and view all the answers

What is the primary mechanism of action of pramlintide in diabetes management?

<p>Regulating glucose postprandial (A)</p> Signup and view all the answers

What is the primary laboratory test used to diagnose hypothyroidism?

<p>TSH (D)</p> Signup and view all the answers

What is the primary cause of sustained hyperglycemia in diabetes mellitus?

<p>Deficiency in insulin (A)</p> Signup and view all the answers

Which of the following is a characteristic of Type 1 diabetes?

<p>Usually childhood or adolescence onset (A)</p> Signup and view all the answers

What is the primary difference between Type 1 and Type 2 diabetes?

<p>Presence of beta cells (A)</p> Signup and view all the answers

What is a common complication of uncontrolled diabetes?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following oral antidiabetic medications acts on the intestine to delay carbohydrate absorption?

<p>Acarbose (B)</p> Signup and view all the answers

What is the primary mechanism of action of incretin mimetics in the management of diabetes?

<p>Stimulating insulin secretion (D)</p> Signup and view all the answers

What is the primary indication for the use of insulin therapy in Type 2 diabetes?

<p>Patients with inadequate glucose control on oral antidiabetic medications (B)</p> Signup and view all the answers

Which of the following is a long-term complication of uncontrolled diabetes?

<p>Macrovascular disease (A)</p> Signup and view all the answers

In Type 2 diabetes, what is the primary advantage of initiating treatment with lifestyle measures and metformin?

<p>Reducing the risk of macrovascular complications (A)</p> Signup and view all the answers

What is the primary difference between short-acting and long-acting insulins?

<p>Onset and duration of action (C)</p> Signup and view all the answers

Which of the following is a factor that increases insulin needs in a patient with diabetes?

<p>All of the above (D)</p> Signup and view all the answers

What is the primary advantage of using insulin pens and injectors in insulin therapy?

<p>Increased convenience (D)</p> Signup and view all the answers

In diabetes management, when is the peak action of insulin most likely to occur?

<p>At the peak of action (A)</p> Signup and view all the answers

What is the primary difference between Type 1 and Type 2 diabetes in terms of treatment?

<p>Insulin therapy is only required in Type 1 diabetes (C)</p> Signup and view all the answers

How is insulin typically stored?

<p>In a refrigerator (C)</p> Signup and view all the answers

What is the primary purpose of using a sliding scale in insulin therapy?

<p>To individualize insulin dosages based on blood glucose levels (B)</p> Signup and view all the answers

What is the primary mechanism of action of Hemoglobin A1C in diagnosing diabetes?

<p>Measuring blood glucose levels over the previous 2-3 months (D)</p> Signup and view all the answers

What is the primary consequence of diabetic nephropathy?

<p>End-Stage Renal Disease (ESRD) requiring dialysis (C)</p> Signup and view all the answers

What is the primary benefit of self-monitoring blood sugar levels with a glucometer in diabetes management?

<p>Optimizing insulin therapy (B)</p> Signup and view all the answers

What is the primary consequence of gastroparesis in diabetes?

<p>Delayed stomach emptying and nausea/vomiting (D)</p> Signup and view all the answers

What is the primary reason for recommending regular foot checks in diabetes management?

<p>To prevent amputations due to infection (A)</p> Signup and view all the answers

What is the primary benefit of oral glucose tolerance testing in diabetes diagnosis?

<p>Diagnosing diabetes in asymptomatic individuals (B)</p> Signup and view all the answers

What is the primary mechanism of action of diabetic neuropathy?

<p>Nerve degeneration (B)</p> Signup and view all the answers

What is the primary consequence of hypertension in diabetes?

<p>Increased risk of heart disease and stroke (C)</p> Signup and view all the answers

What is the effect of weight reduction on insulin needs?

<p>It decreases insulin needs (D)</p> Signup and view all the answers

Which of the following oral antidiabetic medications does not cause hypoglycemia?

<p>Metformin (A)</p> Signup and view all the answers

What is the primary benefit of using biguanides in younger and obese patients?

<p>It may actually prevent diabetes (D)</p> Signup and view all the answers

Which of the following oral antidiabetic medications is chemically related to sulfonamide antibacterial medications?

<p>Glyburide (C)</p> Signup and view all the answers

What is the primary mechanism of action of meglitinides?

<p>Stimulating insulin release (D)</p> Signup and view all the answers

What is the primary advantage of using thiazolidinediones in the treatment of type 2 diabetes?

<p>They decrease insulin resistance (D)</p> Signup and view all the answers

Which of the following oral antidiabetic medications acts on the intestine to delay carbohydrate absorption?

<p>Acarbose (B)</p> Signup and view all the answers

What is the primary side effect of lactic acidosis, a rare but serious side effect of metformin?

<p>Alcohol consumption (D)</p> Signup and view all the answers

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