Diabetes Management: Insulin and Amylin Agonist Drugs
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Questions and Answers

Which drug class stimulates hepatic glycogen synthesis and may be used in combination with oral agents or amylin agonists?

  • Incretin mimetics
  • Dipeptidyl peptidase IV (DPP IV) inhibitors
  • Insulin (correct)
  • Amylin agonist
  • What is the primary function of an Amylin agonist like Pramlintide?

  • Decrease hepatic glucose output
  • Enhance post-prandial control
  • Suppress appetite (correct)
  • Prevent incretin hormone breakdown
  • Which drug class increases beta cell growth and replication and slows gastric emptying time?

  • Sulfonylurea
  • Incretin mimetics (correct)
  • Dipeptidyl peptidase IV (DPP IV) inhibitors
  • Amylin agonist
  • Which drug class prevents the inactivation of incretin hormones by the enzyme DPP IV during hyperglycemia?

    <p>Incretin mimetics</p> Signup and view all the answers

    Which drug class is a first-generation insulin secretagogue that includes Tolbutamide and Chlorpropamide?

    <p>Sulfonylurea</p> Signup and view all the answers

    What is the primary function of Dipeptidyl peptidase IV (DPP IV) inhibitors like Sitagliptin?

    <p>Prevent incretin hormone breakdown</p> Signup and view all the answers

    Which class of antidiabetic drugs is associated with a risk of thrombocytopenia and diabetes management?

    <p>Meglitinide &amp; Phenylalanine derivatives</p> Signup and view all the answers

    What is the mechanism of action of Alpha-glucosidase inhibitors in managing diabetes?

    <p>Competitive inhibition of ATP-sensitive potassium channels</p> Signup and view all the answers

    Which antidiabetic drug class is known to bind to ATP-sensitive potassium channels to increase beta cell sensitivity to glucose?

    <p>Meglitinide &amp; Phenylalanine derivatives</p> Signup and view all the answers

    What is the primary function of Sodium-glucose cotransporter inhibitors in diabetes management?

    <p>Inhibit hepatic glucose output</p> Signup and view all the answers

    Which antidiabetic drug class is typically avoided due to its protein-bound nature and potential for drug-drug interactions?

    <p>Meglitinide &amp; Phenylalanine derivatives</p> Signup and view all the answers

    How do Thiazolidinediones exert their beneficial effects on fasting blood glucose levels in diabetes management?

    <p>Promote glucose uptake by fat and muscles</p> Signup and view all the answers

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