Diabetes Management: Insulin and Amylin Agonist Drugs

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Questions and Answers

Which drug class stimulates hepatic glycogen synthesis and may be used in combination with oral agents or amylin agonists?

  • Incretin mimetics
  • Dipeptidyl peptidase IV (DPP IV) inhibitors
  • Insulin (correct)
  • Amylin agonist

What is the primary function of an Amylin agonist like Pramlintide?

  • Decrease hepatic glucose output
  • Enhance post-prandial control
  • Suppress appetite (correct)
  • Prevent incretin hormone breakdown

Which drug class increases beta cell growth and replication and slows gastric emptying time?

  • Sulfonylurea
  • Incretin mimetics (correct)
  • Dipeptidyl peptidase IV (DPP IV) inhibitors
  • Amylin agonist

Which drug class prevents the inactivation of incretin hormones by the enzyme DPP IV during hyperglycemia?

<p>Incretin mimetics (B)</p> Signup and view all the answers

Which drug class is a first-generation insulin secretagogue that includes Tolbutamide and Chlorpropamide?

<p>Sulfonylurea (A)</p> Signup and view all the answers

What is the primary function of Dipeptidyl peptidase IV (DPP IV) inhibitors like Sitagliptin?

<p>Prevent incretin hormone breakdown (C)</p> Signup and view all the answers

Which class of antidiabetic drugs is associated with a risk of thrombocytopenia and diabetes management?

<p>Meglitinide &amp; Phenylalanine derivatives (B)</p> Signup and view all the answers

What is the mechanism of action of Alpha-glucosidase inhibitors in managing diabetes?

<p>Competitive inhibition of ATP-sensitive potassium channels (C)</p> Signup and view all the answers

Which antidiabetic drug class is known to bind to ATP-sensitive potassium channels to increase beta cell sensitivity to glucose?

<p>Meglitinide &amp; Phenylalanine derivatives (B)</p> Signup and view all the answers

What is the primary function of Sodium-glucose cotransporter inhibitors in diabetes management?

<p>Inhibit hepatic glucose output (A)</p> Signup and view all the answers

Which antidiabetic drug class is typically avoided due to its protein-bound nature and potential for drug-drug interactions?

<p>Meglitinide &amp; Phenylalanine derivatives (B)</p> Signup and view all the answers

How do Thiazolidinediones exert their beneficial effects on fasting blood glucose levels in diabetes management?

<p>Promote glucose uptake by fat and muscles (D)</p> Signup and view all the answers

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