Dexamethasone Flashcards
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Questions and Answers

What is the class for Dexamethasone?

Corticosteroid, anti-inflammatory

What is the MOA for Dexamethasone?

A synthetic steroid that suppresses acute and chronic inflammation. This reduces bronchial hyperactivity and decreases mucus production. In addition, corticosteroids increase the number and responsiveness of beta 2 receptors in the lungs.

What are the pharmacokinetics of Dexamethasone?

Onset: within 1 hour if given IV or IM; 1-2 hours if given PO

What are the indications for Dexamethasone?

<p>Moderate to severe asthma/COPD; Severe allergic reaction; Croup</p> Signup and view all the answers

What are the contraindications for Dexamethasone?

<p>Known hypersensitivity to corticosteroids</p> Signup and view all the answers

What are precautions for Dexamethasone?

<p>May cause hypertension and hyperglycemia</p> Signup and view all the answers

What are the side effects of Dexamethasone?

<p>Nausea, vomiting, headache, or dizziness</p> Signup and view all the answers

What is the dosage for Dexamethasone?

<p>Adult: 10mg IV, IO, IM, or PO; Pediatric: 0.3mg/kg IV, IO, IM or PO</p> Signup and view all the answers

Study Notes

Dexamethasone Overview

  • Dexamethasone is classified as a corticosteroid, primarily used for its anti-inflammatory properties.

Mechanism of Action

  • Acts as a synthetic steroid, effectively suppressing both acute and chronic inflammation.
  • Reduces bronchial hyperactivity and decreases mucus production in the respiratory system.
  • Enhances both the number and responsiveness of beta 2 adrenergic receptors in the lungs.

Pharmacokinetics

  • Rapid onset of action: within 1 hour when administered via IV or IM; 1-2 hours for oral administration.

Indications

  • Effective treatment for moderate to severe asthma and COPD.
  • Utilized in managing severe allergic reactions and croup.

Contraindications

  • Use is contraindicated in patients with known hypersensitivity to corticosteroids.

Precautions

  • Monitoring is required as Dexamethasone may cause hypertension and hyperglycemia.

Side Effects

  • Common side effects include nausea, vomiting, headache, and dizziness.

Dosage Guidelines

  • Adult dosage: 10 mg can be given via IV, IO, IM, or orally.
  • Pediatric dosage: 0.3 mg/kg through IV, IO, IM, or orally.

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Description

Test your knowledge on Dexamethasone, a corticosteroid used for its anti-inflammatory properties. This quiz covers its class, mechanism of action, and pharmacological details to enhance your learning. Perfect for students in pharmacology or healthcare fields.

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