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Questions and Answers
What is the class for Dexamethasone?
Corticosteroid, anti-inflammatory
What is the MOA for Dexamethasone?
A synthetic steroid that suppresses acute and chronic inflammation. This reduces bronchial hyperactivity and decreases mucus production. In addition, corticosteroids increase the number and responsiveness of beta 2 receptors in the lungs.
What are the pharmacokinetics of Dexamethasone?
Onset: within 1 hour if given IV or IM; 1-2 hours if given PO
What are the indications for Dexamethasone?
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What are the contraindications for Dexamethasone?
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What are precautions for Dexamethasone?
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What are the side effects of Dexamethasone?
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What is the dosage for Dexamethasone?
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Study Notes
Dexamethasone Overview
- Dexamethasone is classified as a corticosteroid, primarily used for its anti-inflammatory properties.
Mechanism of Action
- Acts as a synthetic steroid, effectively suppressing both acute and chronic inflammation.
- Reduces bronchial hyperactivity and decreases mucus production in the respiratory system.
- Enhances both the number and responsiveness of beta 2 adrenergic receptors in the lungs.
Pharmacokinetics
- Rapid onset of action: within 1 hour when administered via IV or IM; 1-2 hours for oral administration.
Indications
- Effective treatment for moderate to severe asthma and COPD.
- Utilized in managing severe allergic reactions and croup.
Contraindications
- Use is contraindicated in patients with known hypersensitivity to corticosteroids.
Precautions
- Monitoring is required as Dexamethasone may cause hypertension and hyperglycemia.
Side Effects
- Common side effects include nausea, vomiting, headache, and dizziness.
Dosage Guidelines
- Adult dosage: 10 mg can be given via IV, IO, IM, or orally.
- Pediatric dosage: 0.3 mg/kg through IV, IO, IM, or orally.
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Description
Test your knowledge on Dexamethasone, a corticosteroid used for its anti-inflammatory properties. This quiz covers its class, mechanism of action, and pharmacological details to enhance your learning. Perfect for students in pharmacology or healthcare fields.
