Dexamethasone as Adjunctive Treatment for Meningitis

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What is the recommended intravenous dose of dexamethasone for infants and children with H.influenzae meningitis?

0.15 mg/kg every 6 hours for 2–4 days

When should adjunctive dexamethasone be initiated in infants and children with H.influenzae meningitis?

10–20 minutes prior to or concomitant with the first dose of antibiotics

Which pathogen may prompt the consideration of using adjunctive dexamethasone in infants and children after evaluating benefits and risks?

S.pneumoniae

What is the recommended dose of dexamethasone for adults suspected or confirmed to have pneumococcal meningitis?

0.15 mg/kg (up to 10 mg) every 6 hours for 2–4 days

How is N.meningitidis primarily transmitted among individuals?

Via respiratory droplets and pharyngeal secretions

What may serve as a key indicator that the pathogen causing meningitis is N.meningitidis?

Petechiae on the skin

Interpretation Question: Based on the text, what is the main purpose of administering dexamethasone alongside antibiotics in treating bacterial meningitis?

To reduce inflammation and modulate the immune response

Interpretation Question: What does the text suggest about dexamethasone as a treatment for H.influenzae meningitis in comparison to pneumococcal meningitis?

It may be considered in both cases based on benefits and risks

Interpretation Question: Why is it important to differentiate between different pathogens causing bacterial meningitis?

To assess whether adjunctive therapies like dexamethasone should be considered

Learn about the use of dexamethasone as an adjunctive therapy in the treatment of acute bacterial meningitis, particularly in infants and children with H. influenzae meningitis. Understand the recommended dosage and timing for administering dexamethasone along with antibiotics.

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