Dexamethasone as Adjunctive Treatment for Meningitis

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Questions and Answers

What is the recommended intravenous dose of dexamethasone for infants and children with H.influenzae meningitis?

  • 0.15 mg/kg every 8 hours for 2–4 days
  • 0.2 mg/kg every 6 hours for 1–3 days
  • 0.1 mg/kg every 6 hours for 2–4 days
  • 0.15 mg/kg every 6 hours for 2–4 days (correct)

When should adjunctive dexamethasone be initiated in infants and children with H.influenzae meningitis?

  • Once bacterial cultures are confirmed
  • During the first administration of antibiotics
  • 10–20 minutes prior to or concomitant with the first dose of antibiotics (correct)
  • 24 hours after starting antibiotics

Which pathogen may prompt the consideration of using adjunctive dexamethasone in infants and children after evaluating benefits and risks?

  • H.influenzae
  • N.meningitidis
  • S.pneumoniae (correct)
  • None of the above

What is the recommended dose of dexamethasone for adults suspected or confirmed to have pneumococcal meningitis?

<p>0.15 mg/kg (up to 10 mg) every 6 hours for 2–4 days (B)</p> Signup and view all the answers

How is N.meningitidis primarily transmitted among individuals?

<p>Via respiratory droplets and pharyngeal secretions (B)</p> Signup and view all the answers

What may serve as a key indicator that the pathogen causing meningitis is N.meningitidis?

<p><em>Petechiae</em> on the skin (B)</p> Signup and view all the answers

Interpretation Question: Based on the text, what is the main purpose of administering dexamethasone alongside antibiotics in treating bacterial meningitis?

<p><em>To reduce inflammation and modulate the immune response</em> (C)</p> Signup and view all the answers

Interpretation Question: What does the text suggest about dexamethasone as a treatment for H.influenzae meningitis in comparison to pneumococcal meningitis?

<p><em>It may be considered in both cases based on benefits and risks</em> (B)</p> Signup and view all the answers

Interpretation Question: Why is it important to differentiate between different pathogens causing bacterial meningitis?

<p><em>To assess whether adjunctive therapies like dexamethasone should be considered</em> (D)</p> Signup and view all the answers

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