Developmental Biology and Cloning
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Questions and Answers

Which substance can cause congenital disorders in a developing embryo or fetus?

  • Alcohol (correct)
  • Sugar
  • Protein
  • Caffeine
  • What drug prescribed for morning sickness caused mutations in the SALL4 transcription factor and led to birth defects?

  • Ibuprofen
  • Tylenol
  • Aspirin
  • Thalidomide (correct)
  • What genetic disorder accelerates aging and shortens lifespan?

  • Huntington's disease
  • Cystic fibrosis
  • Progeria (correct)
  • Sickle cell anemia
  • What is Fragile X Syndrome caused by?

    <p>A lack of the FMR1 protein</p> Signup and view all the answers

    What are some factors that influence longevity?

    <p>All of the above</p> Signup and view all the answers

    What are some limitations of cloning?

    <p>More mutations and environmental differences</p> Signup and view all the answers

    Who was the first mammal cloned from adult cells?

    <p>Dolly the Sheep</p> Signup and view all the answers

    What can affect cloning and lead to differences in physical and behavioral traits?

    <p>Epigenetic factors</p> Signup and view all the answers

    What are some ethical concerns about human cloning?

    <p>Rights of clones and implications for generational wealth and crime</p> Signup and view all the answers

    What factors influence development and aging?

    <p>All of the above</p> Signup and view all the answers

    Which substance can cause congenital disorders in a developing embryo or fetus?

    <p>Alcohol</p> Signup and view all the answers

    What drug prescribed for morning sickness caused mutations in the SALL4 transcription factor and led to birth defects?

    <p>Thalidomide</p> Signup and view all the answers

    What genetic disorder accelerates aging and shortens lifespan?

    <p>Progeria</p> Signup and view all the answers

    What is Fragile X Syndrome caused by?

    <p>A lack of the FMR1 protein</p> Signup and view all the answers

    What are some factors that influence longevity?

    <p>All of the above</p> Signup and view all the answers

    What are some limitations of cloning?

    <p>More mutations and environmental differences</p> Signup and view all the answers

    Who was the first mammal cloned from adult cells?

    <p>Dolly the Sheep</p> Signup and view all the answers

    What can affect cloning and lead to differences in physical and behavioral traits?

    <p>Epigenetic factors</p> Signup and view all the answers

    What are some ethical concerns about human cloning?

    <p>Rights of clones and implications for generational wealth and crime</p> Signup and view all the answers

    What factors influence development and aging?

    <p>All of the above</p> Signup and view all the answers

    Which substance is considered a teratogen that can cause congenital disorders in a developing embryo or fetus?

    <p>Alcohol</p> Signup and view all the answers

    What is the genetic disorder that accelerates aging and shortens lifespan?

    <p>Progeria</p> Signup and view all the answers

    Which drug prescribed for morning sickness caused mutations in the SALL4 transcription factor and led to birth defects?

    <p>Thalidomide</p> Signup and view all the answers

    Which protein is lacking in Fragile X Syndrome, causing atypical brain development?

    <p>FMR1</p> Signup and view all the answers

    What is the first mammal cloned from adult cells, but had shorter telomeres and died young?

    <p>Dolly the Sheep</p> Signup and view all the answers

    Which factors influence longevity?

    <p>Immune function, insulin secretion, and stress response</p> Signup and view all the answers

    Which condition is NOT associated with epigenetic factors according to the text?

    <p>Cancer</p> Signup and view all the answers

    What are the potential implications of human cloning according to the text?

    <p>Generational wealth and crime</p> Signup and view all the answers

    Which medication has been associated with higher rates of ADHD and ASD in children, according to the text?

    <p>Tylenol</p> Signup and view all the answers

    What are some substances that can act as teratogens according to the text?

    <p>Alcohol, cigarettes, and recreational drugs</p> Signup and view all the answers

    Study Notes

    Factors Affecting Development and Cloning

    • Teratogens are substances that cause congenital disorders in a developing embryo or fetus, including alcohol, cigarettes, recreational drugs, medications, and infections/viruses.
    • Thalidomide, a drug prescribed for morning sickness, caused mutations in the SALL4 transcription factor and changed the growth and development of new blood vessels, leading to birth defects.
    • Tylenol exposure during pregnancy has been associated with higher rates of ADHD and ASD in children, but it is unclear if the medication itself causes these conditions.
    • Progeria is a genetic disorder that accelerates aging and shortens lifespan, caused by a variant in the LMNA gene that prevents DNA repair.
    • Longevity is influenced by various genes related to immune function, insulin secretion, stress response, cell cycle, DNA repair, lipid metabolism, nutrient metabolism, and antioxidant enzymes.
    • Fragile X Syndrome is caused by a lack of the FMR1 protein needed for typical brain development, and epigenetic factors can influence the onset of mental illnesses like schizophrenia, bipolar disorder, Alzheimer's disease, autism spectrum disorders, cardiovascular disease, obesity, and diabetes.
    • Clones are not exact replicas of their donors due to premature cellular aging, altered gene expression, more mutations, X chromosome inactivation, mitochondrial DNA, and environmental differences.
    • Dolly the Sheep was the first mammal cloned from adult cells, but she had shorter telomeres and died young, highlighting the limitations of cloning.
    • Cloning can be affected by epigenetic factors that alter gene expression and lead to differences in physical and behavioral traits.
    • Human cloning is a controversial topic, with ethical concerns about the rights of clones and implications for generational wealth and crime.
    • Development and aging are influenced by various factors, such as lifestyle choices, genetic predisposition, and environmental exposures.
    • Understanding the role of genetics and epigenetics in development and cloning can inform medical treatments and ethical debates.

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    Description

    Test your knowledge on the fascinating world of developmental biology and cloning with this quiz! From the impact of teratogens and genetic mutations to the limitations and ethical concerns of cloning, this quiz covers a range of factors that affect development and cloning. With questions on topics such as Fragile X Syndrome, progeria, and the controversial topic of human cloning, this quiz will challenge your understanding of genetics and epigenetics. Whether you're a biology buff or just curious about the science behind development and cloning

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