Recent

  • Show all results for ""
Development of Human Lung Anatomy
40 Questions
0 Views

Development of Human Lung Anatomy

Created by
@VeritableJadeite

Questions and Answers

What is the primary function of the lateral plate mesoderm in early embryonic development?

  • Initiating limb development
  • Forming the endoderm layer
  • Creating the neural tube
  • Splitting to form the primitive body cavity (correct)

    • Which layer is continuous with the ectoderm during the formation of the body cavity?

  • Parietal mesoderm
  • Somatic mesoderm (correct)
  • Endoderm
  • Splanchnic mesoderm

    • What key structure begins to form during the 4th week of embryonic development?

  • Placenta
  • Lateral body wall folds (correct)
  • Neural crest
  • Cardiac tube

    • Which layer does the parietal layer of the lateral plate mesoderm overlay?

    <p>Ectoderm</p> Signup and view all the answers

    What occurs at the end of the 3rd week regarding the intra embryonic mesoderm?

    <p>It folds ventrally to form the gut tube</p> Signup and view all the answers

    What is a characteristic of the lateral plate mesoderm during embryo development?

    <p>It splits to form different layers</p> Signup and view all the answers

    Which embryonic component is involved in the closure of the gut tube?

    <p>Endoderm layer</p> Signup and view all the answers

    What concept does the term 'lateral somitic frontier' refer to?

    <p>Separation of somites from lateral plate mesoderm</p> Signup and view all the answers

    What role does the dorsal mesentery play in relation to the gut tube?

    <p>It suspends the gut tube from the posterior body wall.</p> Signup and view all the answers

    Where does the ventral mesentery exist in the gastrointestinal system?

    <p>From the caudal foregut to the upper portion of the duodenum.</p> Signup and view all the answers

    What do the layers of the peritoneum formed by mesenteries consist of?

    <p>Outer parietal and inner visceral layers.</p> Signup and view all the answers

    What is the septum transversum primarily composed of?

    <p>Thick plate of mesodermal tissue.</p> Signup and view all the answers

    What is a primary function of the mesenteries during development?

    <p>To provide a pathway for blood vessels and nerves.</p> Signup and view all the answers

    At which anatomical junction do the lateral plate mesoderm connect with one another?

    <p>At the junction of the gut tube with the posterior body wall.</p> Signup and view all the answers

    Which statement about the abdominal cavity is incorrect?

    <p>The visceral layer is not associated with blood vessel pathways.</p> Signup and view all the answers

    What is the primary characteristic of the dorsal mesentery?

    <p>It extends from the caudal limit of the foregut to the end of the hindgut.</p> Signup and view all the answers

    From which pharyngeal arches do the cartilages and muscles of the larynx arise?

    <p>4th and 6th pharyngeal arches</p> Signup and view all the answers

    Which nerve branch innervates the laryngeal structures derived from the 4th pharyngeal arch?

    <p>Superior laryngeal branch</p> Signup and view all the answers

    What condition was observed in a male fetus with Trisomy 18 at 17 weeks?

    <p>Tracheoesophageal fistula</p> Signup and view all the answers

    Which embryonic structure initially lies opposite the cervical somites during the fourth week of development?

    <p>Septum transversum</p> Signup and view all the answers

    At which developmental week does the upper esophageal segment typically end blindly in the scenario presented?

    <p>17 weeks</p> Signup and view all the answers

    What anatomical structure gives rise to the 3rd and 4th pharyngeal areas during embryonic development?

    <p>Pharyngeal pouch</p> Signup and view all the answers

    What is the role of retinoic acid (RA) in lung bud formation?

    <p>Upregulates transcription factor TBX4</p> Signup and view all the answers

    What do the phrenic nerves develop from during the embryonic stage?

    <p>Cervical spinal cord components</p> Signup and view all the answers

    During which embryonic week does the laryngeal groove form?

    <p>5 weeks</p> Signup and view all the answers

    Which of the following options correctly describes the origin of the epithelium of the internal lining of the trachea?

    <p>Endodermal derivatives</p> Signup and view all the answers

    What is the significance of surgical repair in the context of neonatal or utero interventions?

    <p>It is associated with high survival rates.</p> Signup and view all the answers

    Which transcription factor is specifically induced by retinoic acid during lung development?

    <p>TF TBX4</p> Signup and view all the answers

    At what stage does significant growth of the lungs into the body cavity occur?

    <p>Mid-gestation period (16-20 weeks)</p> Signup and view all the answers

    What does the mesoderm form in relation to the respiratory system during embryonic development?

    <p>Carilage, muscle, and connective tissue</p> Signup and view all the answers

    How does the location of the lung bud change during development?

    <p>It shifts progressively caudally towards the diaphragm</p> Signup and view all the answers

    Which embryonic structure forms the lung bud?

    <p>The endoderm of the gut tube</p> Signup and view all the answers

    What is the role of signaling molecules in lung development?

    <p>They facilitate endodermal/mesenchymal interactions crucial for lung formation.</p> Signup and view all the answers

    Which period of lung development is characterized by the formation of the air-blood barrier?

    <p>Terminal Sac Period</p> Signup and view all the answers

    What embryonic structure contributes to the separation of pleural and pericardial cavities?

    <p>Pleuropericardial Folds</p> Signup and view all the answers

    During which weeks does the pseudoglandular period occur in lung development?

    <p>5-17 Weeks</p> Signup and view all the answers

    Which layer of mesoderm is involved in the development of lung tissue?

    <p>Splanchnic Layer of Lateral Plate Mesoderm</p> Signup and view all the answers

    Congenital diaphragmatic hernia primarily affects which aspect of lung growth?

    <p>The overall expansion of the lung within the thoracic cavity.</p> Signup and view all the answers

    What factor enhances the function of the lungs during the later stages of development?

    <p>Surfactant Proteins</p> Signup and view all the answers

    The initial patterning of the lung occurs during which phase of development?

    <p>Pseudoglandular Period</p> Signup and view all the answers

    Study Notes

    GROWTH of LUNGS into the BODY CAVITY

    • Pleural membranes differentiate to establish the pleural and pericardial cavities.
    • Pleuropericardial folds serve as the dividing structures between the pleural and pericardial cavities.
    • The septum transversum partially separates abdominal and thoracic cavities during development.
    • Congenital diaphragmatic hernia: a developmental defect leading to displacement of abdominal organs into the thoracic cavity.
    • Initial lung patterning occurs within the developing embryo.

    DEVELOPMENT of HUMAN LUNG

    • Endodermal and mesenchymal interactions play a crucial role in lung development.
    • Key signaling molecules facilitate various stages of lung maturation.
    • Lung development occurs in distinct stages:
      • Pseudoglandular Period (5-17 Weeks): Initial branching of the lung.
      • Canalicular Period (16-26 Weeks): Formation of airways and vascularization.
      • Terminal Sac Period (26 Weeks to Birth): Development of alveoli and respiratory surface.
      • Alveolar Period (Late Fetal to Age 8): Maturation of alveoli for efficient gas exchange.
    • Surfactant proteins are crucial for lung function, reducing surface tension in alveoli.

    CLINICAL CORRELATIONS

    • Respiratory distress syndrome: Common in premature infants due to surfactant deficiency.
    • Hyaline membrane disease: A significant cause of respiratory failure in neonates.
    • Congenital lung cysts: Fluid-filled sacs that can affect lung development.
    • Agenesis of lungs: Complete absence of lung tissue, poses serious health risks.
    • Lung hypoplasia: Underdevelopment of lung tissue contributes to respiratory distress.
    • Diaphragmatic hernias: Abnormal displacement of abdominal organs into the thoracic cavity.

    THE GUT TUBE AND THE BODY CAVITIES

    • By the end of the 3rd week, intra-embryonic mesoderm folds ventrally, forming the gut tube.
    • The abdominal cavity is suspended by the dorsal mesentery, anchoring the gut tube to the posterior body wall.
    • Ventral mesentery exists only from the caudal foregut to the upper duodenum, originating from the septum transversum.
    • The diaphragm plays a key role in thoracic cavity formation, with the septum transversum being a significant structural component.

    LARYNX and TRACHEA Development

    • Phrenic nerves innervate the diaphragm, originating from cervical spinal segments.
    • Lung bud formation is driven by increased retinoic acid (RA) from adjacent mesoderm, influencing TBX4 expression and respiratory diverticulum development.
    • Cartilages and muscles of the larynx develop from mesenchyme associated with pharyngeal arches, innervated by branches of the vagus nerves.

    SURGICAL REPAIR

    • Surgical interventions for respiratory conditions lead to significantly improved survival rates, now exceeding 85%.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    Explore the developmental process of the human lung and its anatomical features. This quiz covers key topics such as the differentiation of pleural membranes and the formation of cavities related to the lungs. Test your knowledge on congenital conditions and patterns in lung development.

    More Quizzes Like This

    Human Lung Anatomy
    6 questions

    Human Lung Anatomy

    AppreciativeWalrus avatar
    AppreciativeWalrus
    Boundaries of Lung and Pleura
    18 questions

    Boundaries of Lung and Pleura

    HolyUnity avatar
    HolyUnity
    Lung Volumes and Lung Capacities Quiz
    10 questions

    Lung Capacity Quiz: Test Your Knowledge of Lung Volumes and Capacities

    StateOfTheArtExtraterrestrial avatar
    StateOfTheArtExtraterrestrial
    Embriología del sistema respiratorio
    10 questions

    Embriología del sistema respiratorio

    InstructivePortland avatar
    InstructivePortland
    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser