3-L2 Skin

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Questions and Answers

What is the characteristic appearance of a psoriasis patch?

Circumscribed red patch with white scales

What is the main cause of psoriasis?

Increase in the number of proliferating cells

What is the result of the increased cell proliferation in psoriasis?

Greater epidermal thickness and more rapid renewal of epidermis

What is the characteristic of pemphigus, a type of blistering disorder?

Autoimmune damage to skin cells Signup and view all the answers

What is affected in pemphigus, leading to blistering?

Intercellular junctions between keratinocytes Signup and view all the answers

What is the relationship between keratinocytes in pemphigus?

They are damaged, disrupting intercellular junctions Signup and view all the answers

What is the name of the layer of the epidermis where cells are constantly mitotically active?

Stratum basale Signup and view all the answers

What type of cells are found in the Stratum basale?

Keratinocytes, melanocytes, and merkel's cells Signup and view all the answers

What is the function of Keratohyalin granules in the Stratum granulosum?

To associate with keratin filaments Signup and view all the answers

Which of the following is NOT a characteristic of Stratum spinosum?

It is the thickest layer of the epidermis Signup and view all the answers

What is the name of the layer that is only present in thick skin?

Stratum lucidum Signup and view all the answers

What is the approximate time it takes for the cells in the Stratum basale to turnover?

15-30 days Signup and view all the answers

What is the location of the stratum lucidum in the skin?

Superficial to the stratum granulosum Signup and view all the answers

What is unique about the cells in the stratum lucidum?

They are densely packed with keratin filaments parallel to the skin surface Signup and view all the answers

What is the function of the extracellular lipids in the stratum corneum?

To form a water barrier Signup and view all the answers

Which layer of the epidermis varies most in thickness?

Stratum corneum Signup and view all the answers

What is the characteristic of the cells in the stratum corneum?

They are flat and filled with keratin Signup and view all the answers

What is the function of the keratin filaments in the stratum lucidum?

To provide mechanical strength Signup and view all the answers

Where is tyrosinase synthesized?

Rough endoplasmic reticulum Signup and view all the answers

What is the stage where melanin synthesis begins?

Stage II melanosomes Signup and view all the answers

What is the result of melanocyte activity?

Amount of melanin granules Signup and view all the answers

What is the function of stage III melanosomes?

Melanin accumulation Signup and view all the answers

What is the final destination of melanin granules?

Keratinocytes of the malpighian layer Signup and view all the answers

What varies in different regions of skin of an individual?

Number of melanocytes/square mm Signup and view all the answers

What is the average surface area of the skin in adults?

1-2 m^2 Signup and view all the answers

How much does the skin weigh in adults?

3-5 kg Signup and view all the answers

What is the function of the skin as a physical barrier?

To protect against thermal and mechanical insults Signup and view all the answers

What is the composition of the skin?

Epidermis and dermis Signup and view all the answers

What is the purpose of the skin's sensory function?

To constantly monitor the environment Signup and view all the answers

What is the thickness of the epidermis in thin skin?

75-150 micrometers Signup and view all the answers

What is the function of the skin related to calcium metabolism?

To synthesize vitamin D3 Signup and view all the answers

What is the relationship between the dermis and epidermis?

The junction of dermis and epidermis is irregular Signup and view all the answers

What is the location of the subcutaneous tissue?

Below the dermis Signup and view all the answers

What is the thickness of the epidermis in thick skin?

400-1400 micrometers Signup and view all the answers

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