Depurination and DNA Mutations Quiz

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Questions and Answers

What is depurination?

  • The addition of pyrimidines to a nucleotide
  • The addition of purines to a nucleotide
  • The loss of pyrimidines from a nucleotide
  • The loss of purines from a nucleotide (correct)

How does depurination cause mutation?

  • By creating a deletion mutation (correct)
  • By inducing a transversion mutation
  • By inducing a transition mutation
  • By creating an insertion mutation

What type of nucleotides are lost during depurination?

  • Guanine or uracil
  • Cytosine or thymine
  • Uracil or cytosine
  • Adenine or guanine (correct)

What enzyme recognizes and corrects depurinated sites?

<p>DNA repair enzymes (B)</p> Signup and view all the answers

What happens if a depurinated site is not corrected?

<p>DNA polymerase will skip the depurinated site during replication (A)</p> Signup and view all the answers

What type of mutation is created when a depurinated site is not corrected?

<p>Deletion mutation (C)</p> Signup and view all the answers

What happens to the depurinated nucleotide in successive replications?

<p>It is eventually removed, creating a permanent deletion mutation in one copy (D)</p> Signup and view all the answers

What type of hydrolysis reaction causes depurination?

<p>Spontaneous hydrolysis reaction (C)</p> Signup and view all the answers

What is depurination?

<p>The loss of purines from a nucleotide (B)</p> Signup and view all the answers

What causes depurination?

<p>A spontaneous hydrolysis reaction (B)</p> Signup and view all the answers

What happens if a depurinated site is not corrected?

<p>The DNA polymerase will skip it during replication and create a deletion mutation (C)</p> Signup and view all the answers

Which nucleotides are lost during depurination?

<p>Adenine or guanine (D)</p> Signup and view all the answers

What is the result of successive replications after depurination?

<p>A permanent deletion mutation (A)</p> Signup and view all the answers

What do DNA repair enzymes do when they recognize a depurinated site?

<p>They recognize and correct the depurinated site (A)</p> Signup and view all the answers

Which enzyme skips the depurinated site during replication?

<p>DNA polymerase (A)</p> Signup and view all the answers

What type of mutation is created when DNA polymerase skips a depurinated site during replication?

<p>Deletion mutation (B)</p> Signup and view all the answers

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