Depurination and DNA Mutations Quiz
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Questions and Answers

What is depurination?

  • The addition of pyrimidines to a nucleotide
  • The addition of purines to a nucleotide
  • The loss of pyrimidines from a nucleotide
  • The loss of purines from a nucleotide (correct)
  • How does depurination cause mutation?

  • By creating a deletion mutation (correct)
  • By inducing a transversion mutation
  • By inducing a transition mutation
  • By creating an insertion mutation
  • What type of nucleotides are lost during depurination?

  • Guanine or uracil
  • Cytosine or thymine
  • Uracil or cytosine
  • Adenine or guanine (correct)
  • What enzyme recognizes and corrects depurinated sites?

    <p>DNA repair enzymes</p> Signup and view all the answers

    What happens if a depurinated site is not corrected?

    <p>DNA polymerase will skip the depurinated site during replication</p> Signup and view all the answers

    What type of mutation is created when a depurinated site is not corrected?

    <p>Deletion mutation</p> Signup and view all the answers

    What happens to the depurinated nucleotide in successive replications?

    <p>It is eventually removed, creating a permanent deletion mutation in one copy</p> Signup and view all the answers

    What type of hydrolysis reaction causes depurination?

    <p>Spontaneous hydrolysis reaction</p> Signup and view all the answers

    What is depurination?

    <p>The loss of purines from a nucleotide</p> Signup and view all the answers

    What causes depurination?

    <p>A spontaneous hydrolysis reaction</p> Signup and view all the answers

    What happens if a depurinated site is not corrected?

    <p>The DNA polymerase will skip it during replication and create a deletion mutation</p> Signup and view all the answers

    Which nucleotides are lost during depurination?

    <p>Adenine or guanine</p> Signup and view all the answers

    What is the result of successive replications after depurination?

    <p>A permanent deletion mutation</p> Signup and view all the answers

    What do DNA repair enzymes do when they recognize a depurinated site?

    <p>They recognize and correct the depurinated site</p> Signup and view all the answers

    Which enzyme skips the depurinated site during replication?

    <p>DNA polymerase</p> Signup and view all the answers

    What type of mutation is created when DNA polymerase skips a depurinated site during replication?

    <p>Deletion mutation</p> Signup and view all the answers

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