42 Questions
What percentage of people who are clinically depressed are likely to commit suicide?
15%
According to the ICD and DSM IV, what is the minimum duration for which a person must experience a lowered mood to be diagnosed with depression?
2 weeks
What is the estimated percentage of women who experience depression?
20-25%
What is the term for depression that occurs in women after childbirth?
Postpartum Depression
What is the mean age of onset for depression?
35-40 years
What is the term for depression that is seasonal in nature?
Seasonal Affective Disorder
What is the impact of urbanization on community psychology?
It leads to a degradation of support structures
What is the primary characteristic of reactive depression?
Increase in stressful life events
What is anhedonia in the context of depression?
Loss of interest in usual activities and pastimes
What is the purpose of the Hamilton rating scale for depression?
To measure the severity of depression
What is the minimum number of symptoms required for a diagnosis of depression?
5
What is the characteristic of a severe depressive episode?
Several marked symptoms, loss of self-esteem, and suicidal thoughts
What is the biogenic amine hypothesis of depression?
Characteristic somatic symptoms implicate amine imbalance
What is the purpose of the PHQ-9?
To measure the severity of depression
What is the impact of genetics on depression?
It is a causative factor of depression
What is the recommended approach to managing depression?
Early identification and prompt and adequate treatment
What is the primary mechanism of action of reserpine as a depressant drug?
Inhibiting neurotransmitter vesicles and preventing NT storage
According to the NICE treatment guidelines, what is the recommended initial treatment for mild depression?
Offering guided self-help based on Cognitive Behavioural Therapy
Which type of therapy focuses on maladaptive perceptions and thoughts?
Cognitive therapy
What is the main difference between reversible and irreversible MAOIs?
Irreversible MAOIs permanently bind to the MAO enzyme, while reversible MAOIs do not
What is the main advantage of using SSRIs over TCAs in the treatment of depression?
SSRIs are less likely to cause side effects compared to TCAs
What is the primary mechanism of action of MAOIs in the treatment of depression?
Inhibiting the action of MAO-A and MAO-B enzymes
What is the recommended treatment for moderate to severe depression in adults?
Combining antidepressant medication with individual CBT
What is the main disadvantage of using MAOIs in the treatment of depression?
MAOIs can interact with certain foods, such as cheese, to cause a hypertensive crisis
What is the primary goal of cognitive therapy in the treatment of depression?
To help the patient identify and challenge maladaptive thoughts
What is the recommended duration of maintenance treatment with antidepressants?
2 years
Which type of antidepressant has a low incidence of drug interactions, but caution should be exercised when given with antihypertensive drugs?
SNRI
What is the primary mechanism of action of NASSA antidepressants?
Enhancing Na+ transmission by blocking α2 autoreceptors
What is the common side effect of TCA antidepressants that is not seen in SSRIs?
Anticholinergic activity
What is the benefit of Agomelatine in treating major depression?
Reduces HAM-D score by +12 points
What is the primary advantage of SSRIs over TCAs?
Extremely low toxicity in overdose
What is the recommended duration of antidepressant treatment for patients with a history of recurrent depression?
Indefinitely
What is the purpose of the 'wash-out' time period when switching between antidepressant medications?
To allow original drug to be fully excreted
What is the common side effect of NASSA antidepressants that is not seen in SSRIs?
Weight gain
Which type of antidepressant has a high affinity for H1 receptors, leading to side effects such as weight gain, drowsiness, and sedation?
NASSA
What is the recommended frequency of review for patients on their first antidepressant prescription?
Every 1-2 weeks
What should be offered as first-line treatment for moderate to severe depression in children and young people?
A specific psychological therapy
In what scenario may antidepressant medication be offered to a child?
In combination with concurrent psychological therapy
What is a factor that may influence the choice of antidepressant for a patient?
The patient's previous success with treatments
What is a treatment option for seasonal affective disorder (SAD)?
Lux-box therapy
What is a disadvantage of electroconvulsive therapy?
It induces an amnesic effect
What is a potential interaction to be aware of when taking St John's Wort?
It interacts with antidepressant medications
This quiz covers the range of depression-related mood disorders, including Major Depressive Disorder, Dysthymia, Seasonal Affective Disorder, Postpartum Depression, and Bipolar Disorder. Understand the diagnostic criteria and classification of depression according to the International Classification of Diseases and the Diagnostic and Statistical Manual of Mental Disorders.
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