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Questions and Answers
What is the role of a buffer solution in the body?
What is the role of a buffer solution in the body?
How does the pH of blood affect a person's health?
How does the pH of blood affect a person's health?
Which components make up a buffer solution?
Which components make up a buffer solution?
Why are buffer solutions crucial for living organisms?
Why are buffer solutions crucial for living organisms?
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How do body cells ensure that pH values are maintained at optimal levels?
How do body cells ensure that pH values are maintained at optimal levels?
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What happens when a small amount of a strong acid or base is added to normal water (non-buffered solution)?
What happens when a small amount of a strong acid or base is added to normal water (non-buffered solution)?
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What is the reaction between an acid and HPO4^-2 according to the given equation?
What is the reaction between an acid and HPO4^-2 according to the given equation?
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What is the reaction between a base and H2PO4- according to the given equation?
What is the reaction between a base and H2PO4- according to the given equation?
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What is the relationship between [HCO3-] and [H2CO3] when the blood is acidic?
What is the relationship between [HCO3-] and [H2CO3] when the blood is acidic?
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What is the pH range where death can occur?
What is the pH range where death can occur?
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What is the primary function of maintaining proper blood pH levels?
What is the primary function of maintaining proper blood pH levels?
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What is the definition of a solution?
What is the definition of a solution?
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Which of the following statements about protein buffers is correct?
Which of the following statements about protein buffers is correct?
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What is the role of hemoglobin in buffering the blood system?
What is the role of hemoglobin in buffering the blood system?
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What is the most important pH buffer system in the blood?
What is the most important pH buffer system in the blood?
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Why is it important to control the pH of the blood?
Why is it important to control the pH of the blood?
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What is the Henderson-Hasselbalch equation used for?
What is the Henderson-Hasselbalch equation used for?
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What is the effect of small changes in the concentration of acetate or acetic acid on the pH of a buffer solution?
What is the effect of small changes in the concentration of acetate or acetic acid on the pH of a buffer solution?
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According to the passage, which of the following is the primary factor that contributes to blood pH imbalance?
According to the passage, which of the following is the primary factor that contributes to blood pH imbalance?
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What is the normal pH range of blood according to the passage?
What is the normal pH range of blood according to the passage?
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What is the relationship between enzyme function and pH according to the figure?
What is the relationship between enzyme function and pH according to the figure?
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Which of the following is the definition of acidosis according to the passage?
Which of the following is the definition of acidosis according to the passage?
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What is the primary effect of hydrogen ion concentration on the body according to the passage?
What is the primary effect of hydrogen ion concentration on the body according to the passage?
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Study Notes
Hydrogen Ion Concentration and Enzyme Function
- Hydrogen ion concentration has a widespread effect on the body's enzyme systems.
- The hydrogen ion is highly reactive and combines with bases or negatively charged ions at very low concentrations.
- Proteins contain many negatively charged and basic groups within their structure, and a change in pH will alter the degree of ionization of a protein, affecting its functioning.
Acid-Base Balance
- Blood is normally slightly basic, alkaline, with a pH range of 7.35 to 7.45.
- The body maintains the pH of blood close to 7.40 to function properly.
- Acidosis: the blood has too much acid (or too little base), resulting in a decrease in blood pH.
- Alkalosis: the blood has too much base (or too little acid), resulting in an increase in blood pH.
Factors Contributing to Blood pH Imbalance
- Two factors contribute to blood pH imbalance: intake, oxygen-carbon dioxide, and dietary habits; and production, elimination, and stress.
pH Levels and Health
- pH levels between 7.35 and 7.45 promote healthy cholesterol levels, healthy blood sugar balance, proper fat metabolism, normal energy balance, disease resistance, and the body's ability to flush toxins.
- Death occurs if blood pH is < 6.8 or > 7.8.
Solutions and Concentration
- A solution is a homogeneous mixture created by dissolving one or more solutes in a solvent.
- The chemical present in a smaller amount is the solute, which is soluble in the solvent (the chemical present in a larger amount).
- Water is a common solvent, forming aqueous solutions, and is one of the best solvents for dissolving ionic substances.
Buffer Solutions and Acid-Base Balance
- A buffer solution is a mixture of a weak acid and a salt of this acid or a weak base and a salt of this base.
- Buffer solutions resist changes in pH when a small amount of a strong acid or base is added.
- Buffer solutions are important in living things because they maintain the acid-base balance in the blood.
Buffer Solutions in the Body
- Protein buffers are the most abundant in the body, and they resist changes in acidity or alkalinity.
- Haemoglobin buffers the blood system using the proteins present, controlling the pH of the blood.
- The most important pH buffer system in the blood involves carbonic acid and bicarbonate ions.
pH Buffer System and Health
- The blood's acid-base balance is controlled by the body because even minor deviations from the normal range can severely affect the brain, arteries, the heart, muscles, and many organs.
- Deviations from the normal pH range can contribute to serious disease, such as cancer.
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Description
Explore the concept of buffer, pH, and acid-base balance in dentistry. Learn how small amounts of strong acids or bases can significantly change the pH of a solution. Understand the importance of maintaining specific pH levels in chemical reactions within the body, such as blood functioning at pH 7.4.